Universal high pressure liquid connector

• US 6,494,500 B1
• Filed: 05/12/2000
• Issued: 12/17/2002
• Est. Priority Date: 05/12/1999
• Status: Expired due to Term

• Current Assignee: Cole-Parmer Instrument Company (Thermo Fisher Scientific Incorporated)
• Original Assignee: Geoff Todosiev, Michael Rigoli
• Inventors: Rigoli, Michael, Todosiev, Geoff
• Primary Examiner(s): Browne, Lynne H.
• Assistant Examiner(s): Cottingham, John R.
• Application Number:
  US09/570,307
• Time in Patent Office: 949 Days
• Field of Search: 285/354, 285/279
• US Class Current: 285/342
• CPC Class Codes: G01N 30/36 in high pressure liquid systems
• CPC Class Codes: G01N 30/6026 Fluid seals
• CPC Class Codes: G01N 30/6034 joining multiple columns

Abstract

The present invention is a universal self-adjusting high pressure liquid connector for use with high pressure liquid chromatography (HPLC) columns requiring liquid-tight and leak free seals between fittings and unions. The present apparatus provides a liquid-tight seal between the end of a HPLC end fitting and a end cap thereby eliminating any potential dead volume in the area of the connection. The apparatus comprises a body, a fixed ferrule, a replaceable ferrule, a stem disposed in the body and a biasing spring slidingly mounted on a capillary tube of that extends through the connector. The spring biases the capillary tube of the connector into the HPLC end fitting, self-adjusting and maintaining a pressure sufficient to ensure a liquid-tight seal notwithstanding the depth of the HPLC tube stop or ferrule stop of the mating HPLC column.

Claims

1. A universal self-adjusting high pressure liquid connector for use in high pressure liquid chromatography (HPLC) comprising:

a body, having a longitudinal bore therethrough, wherein the bore through said body is coincident with longitudinal axis of said body and extends the entire length of said body;

a stem having a longitudinal bore therethrough and a first end and a second end, the first end of said stem at least partally disposed within the longitudinal bore of said body, wherein the bore through said stem is coincident with the longitudinal axis of said body, extends the entire length of said stem and said stem is further sized to fit the longitudinal bore of said body;

an elongate capillary tube disposed within and extending through said stem and said body, said capillary tube having an outer diameter sized to fit snugly yet slidingly within the longitudinal bore of said stem and an inner diameter of a predetermined size;

a fixed ferrule fixedly attached to said capillary tube at a predetermined position on said capillary tube whereby said fixed ferrule is located between the first end of said stem disposed at least partially within said body and said body longitudinal bore;

a bias spring slidingly engaged about said capillary tube within the longitudinal bore of said body between said fixed ferrule and said body within the longitudinal bore of said body whereby engaging end of said stem with an HPLC fitting creates a leakproof seal connection and said spring adjusts and constantly biases said stem in sealed mating relationship with the HPLC fitting, thereby eliminating the potential for a dead volume; and

an opposing fixed depth connector, located on said capillary tube, wherein said capillary tube is configured in a U-shape.

2. The self-adjusting high pressure liquid connector of claim 1 wherein said stem and said body are threadedly engaged one with the other, wherein the first end of said stem is threadedly engaged with said body.

3. The self-adjusting high pressure liquid connector of claim 1 wherein said connector is operably engageable with a HPLC fitting without the use of tools.

4. The self-adjusting high pressure liquid connector of claim 1 wherein at least a portion of an exterior surface of said body is knurled to facilitate the handling of said connector during the engagment of said connector with a HPLC fitting.

5. The self-adjusting high pressure liquid connector of claim 1 wherein said capillary tube may vary in length and inner diameter, and outer diameter.

6. The self-adjusting high pressure liquid connector of claim 1 wherein at least a portion of an exterior surface of said stem is threaded for threaded engagement with a threaded HPLC fitting.

7. The self-adjusting high pressure liquid connector of claim 6 wherein the exterior threads located on the exterior of said stem are located substantially near the second end of said stem.

8. The self-adjusting high pressure liquid connector of claim 6 wherein said the exterior threads located on said stem comprises material having anti-gall metallurgic properties.

9. The self-adjusting high pressure liquid connector of claim 6 wherein said the exterior threads located on said stem comprises NITRONIC-60 material.

10. The self-adjusting high pressure liquid connector of claim 6 wherein said the exterior threads located on said stem comprises GALL-TOUGH material.

11. The universal self-adjusting high pressure liquid connector of claim 1 further comprising a replaceable ferrule slidingly engaged on said capillary tube and seated in intimate contact with the second end of said stem for further ensuring a leakproof connection between the universal self-adjusting high pressure liquid connector and a HPLC fitting when operably engaged.

12. The self-adjusting high pressure liquid connector of claim 11 wherein said replaceable ferrule further comprises a v-shaped groove disposed longitudinally along the outside surface of said ferrule for easier extraction of said ferrule from said insert.