Medical, radiotherapy source vial

• US 6,494,824 B1
• Filed: 02/20/1999
• Issued: 12/17/2002
• Est. Priority Date: 02/20/1998
• Status: Expired due to Term

• Current Assignee: Marc G. Apple
• Original Assignee: Marc G. Apple
• Inventors: Purdy, James D., Apple, Marc G., DeFord, John A., Lane, Joseph P., Miller, Delbert C., Bates, Brian L., Fearnot, Neal E., Frankland, Gregory A.
• Primary Examiner(s): Shaver, Kevin
• Assistant Examiner(s): Cadugan, Joseph A.
• Application Number:
  US09/253,310
• Time in Patent Office: 1,396 Days
• Field of Search: 600/1, 600/3, 600/4, 600/5, 600/7
• US Class Current: 600/3
• CPC Class Codes: A61M 25/10184 Means for controlling or monitoring inflation or deflation
• CPC Class Codes: A61M 25/104 used for angioplasty
• CPC Class Codes: A61M 5/1785 comprising radioactive shield means syringe shields or holders for storage of radioactive sources G21F5/018
• CPC Class Codes: A61M 5/31511 Piston or piston-rod constructions, e.g. connection of piston with piston-rod A61M5/5066 takes precedence
• CPC Class Codes: A61M 5/31515 Connection of piston with piston rod
• CPC Class Codes: A61N 2005/1021 Radioactive fluid
• CPC Class Codes: A61N 5/1002 Intraluminal radiation therapy

Abstract

A catheter apparatus and radiation dosimetry unit indicator for delivery of a prescribed radiation dose to a patient. A radiotherapy source vial (700) includes a fluid container (701) of radioactive fluid with a seal (702,731) disposed about the container. Seal (702,731) is moveable with respect to container (701) to change the contained volume therein. A radioactive fluid transport site (703) is in communication with the contained volume and with an exterior (726) of the container (701), and may include a septum (707) or a valve (711). An engagement mechanism (704) is connectable to an external control mechanism (706) whereby the contained volume in the radioactive fluid container can be decreased and increased by actuation of the external control mechanism.

Claims

1. A radiotherapy source vial (700) comprising:

a radioactive fluid container (701) having a contained volume (705) therein;

an expandable radioactive fluid seal (702, 731) disposed about the radioactive fluid container and being moveable with respect to the radioactive fluid container to change the contained volume therein;

a radioactive fluid transport site (703) disposed about the radioactive fluid container and communicating with the contained volume and an exterior (726) of the radioactive fluid container; and

an engagement mechanism (704) fixedly disposed about at least one of the radioactive fluid container and the radioactive fluid seal and fixedly connectable to an external control mechanism (706) external to the radioactive fluid container, whereby the contained volume in the radioactive fluid container can be decreased and increased by actuation of the external control mechanism.

2. The device of claim 1 wherein the radioactive fluid transport site includes a septum (707) that can be pierced by a needle or cannula (734).

3. The device of claim 2 wherein the radioactive fluid transport site is located on the radioactive fluid seal.

4. The device of claim 2 wherein the radioactive fluid container further includes a coupler (715) attached to the radioactive fluid container for engagement with the external control mechanism such that the external mechanism causes movement of the radioactive fluid container relative the radioactive fluid seal, thereby reducing the volume of the radioactive fluid container.

5. The device of claim 1 wherein the radioactive fluid transport site is a port (708), the port adapted to engage an external delivery conduit (709), thereby opening a passage (710) between the external delivery conduit and the radioactive fluid container.

6. The device of claim 1 wherein the radioactive fluid transport site includes a manually operable valve (711).

7. The device of claim 1 wherein the engagement mechanism comprises a receiver for the external control mechanism.

8. The device of claim 7 wherein the receiver includes threads for receiving a threaded external control mechanism.

9. The device of claim 8 wherein the receiver includes at least one coupling site for locking the external control mechanism with the at least one of the radioactive fluid container and the radioactive fluid seal.

10. A radiotherapy source vial (700) comprising:

a radioactive fluid container (701) having a contained volume (705) therein, the contained volume including an initial contained volume (716);

an expandable radioactive fluid seal (702) disposed about the radioactive fluid container and being moveable with respect to the radioactive fluid container to change the contained volume in therein;

a radioactive fluid transport site (703) disposed about the radioactive fluid container and communicating with the contained volume and an exterior (726) of the radioactive fluid container;

an engagement mechanism (704) fixedly disposed about at least one of the radioactive fluid container and the radioactive fluid seal and fixedly connectable to an external control mechanism (706) external to the radioactive fluid container;

a resilient mechanism (717) disposed within the radioactive fluid container and urging the radioactive fluid seal to a position in the radioactive fluid container at which the contained volume is at the initial contained volume;

and whereby the contained volume in the radioactive fluid container can be decreased and increased by actuation of the external control mechanism.

11. The device of claim 10 wherein the resilient mechanism is a spring (718,719).

12. The device of claim 10 further including a outer shield (720) disposed about the radioactive source container and having at least one opening (721,722) for the passage of radioactive fluid and through which the external control mechanism is introduced.

13. The device of claim 12 wherein the outer shield includes a first (721) and a second (722) opening, the first opening located at one end of the outer shield and through which the external control mechanism is inserted to engage with the engagement mechanism on the radiotherapy source vial, the second opening located at another end of the outer shield and through which radioactive fluid is passed therethrough.

14. The device of claim 13 further comprising a radioactive fluid delivery apparatus that includes a handle mechanism (723), a valve assembly (724), and a carriage (725);

wherein the outer shield and radioactive source container are placed in the carriage which is slidable relative the valve assembly;

the handle mechanism is attachable to the external control mechanism to advance and retract the external control mechanism, whereby adjusting the contained volume of the radioactive source container.

15. A radiotherapy source vial (700) comprising:

a radioactive fluid container (701) having a contained volume (705) therein;

an expandable radioactive fluid seal (702) disposed about the radioactive fluid container and being moveable with respect to the radioactive fluid container to change the contained volume in therein;

a radioactive fluid transport site (703) disposed about the radioactive fluid container and communicating with the contained volume and an exterior (726) of the radioactive fluid container;

an engagement mechanism (704) fixedly disposed about at least one of the radioactive fluid container and the radioactive fluid seal and being at least one of fixedly connected and fixedly connectable to an external control mechanism external to the radioactive fluid container; and

an attachment mechanism (727) having an engaged condition, the attachment mechanism disposed on at least one of the radioactive fluid container, the radioactive fluid seal, and the engagement mechanism and when in the engaged condition, maintaining the contained volume fixed, whereby the contained volume in the radioactive fluid container can be decreased and increased by actuation of the external control mechanism.

16. The device of claim 15 wherein the attachment mechanism is a locking mechanism (728) whereby locking features (739) of the radioactive fluid seal engage locking features located about the radioactive fluid container.

17. The device of claim 16 wherein the locking mechanism (728) includes a partially threaded member (736) having threaded portions (737) that can alternately engage the locking features of the radioactive fluid container or rotatably align with unthreaded channels (738) located between the locking features to allow free longitudinal movement.

18. The device of claim 15 wherein the attachment mechanism comprises at least one of an adhesive (729) and a magnet (730).

19. A radiotherapy source vial (700) comprising:

a radioactive fluid container (701) having a contained volume therein;

an expandable radioactive fluid seal (731) disposed within the radioactive fluid container;

a radioactive fluid transport site (703) disposed about the radioactive fluid container and communicating with the contained volume and an exterior of the radioactive fluid container;

an engagement mechanism fixedly disposed about the radioactive fluid container and fixedly connectable to an external control mechanism external to the radioactive fluid container, whereby the contained volume in the radioactive fluid container can be decreased and increased by actuation of the external control mechanism.

20. The device of claim 19 wherein the expandable radioactive fluid seal comprises an inflatable member (732), and the external control mechanism comprises a fluid supply apparatus (733).