Medical device

• US 6,494,867 B1
• Filed: 03/21/2000
• Issued: 12/17/2002
• Est. Priority Date: 04/28/1999
• Status: Expired due to Fees

• Current Assignee: Jan Skansen, Sten-Olof Elver
• Original Assignee: Jan Skansen, Sten-Olof Elver
• Inventors: Elver, Sten-Olof, Skansen, Jan
• Primary Examiner(s): RIVELL, JOHN A
• Application Number:
  US09/532,521
• Time in Patent Office: 1,001 Days
• Field of Search: 604/502, 604/891.1, 604/257, 604/258, 604/288.03, 604/288.04
• US Class Current: 604/258
• CPC Class Codes: A61M 2205/0244 Micromachined materials, e.g. made from silicon wafers, microelectromechanical systems [MEMS] or comprising nanotechnology
• CPC Class Codes: A61M 2205/3507 with implanted devices, e.g. external control
• CPC Class Codes: A61M 2209/045 for filling, e.g. for filling reservoirs
• CPC Class Codes: A61M 5/1413 Modular systems comprising interconnecting elements
• CPC Class Codes: A61M 5/14276 specially adapted for implantation
• CPC Class Codes: A61M 5/427 Locating point where body is to be pierced, e.g. vein location means using ultrasonic waves, injection site templates

Abstract

Implantable drug delivery system comprising a reservoir module provided with a drug reservoir and a drug expelling means arranged to expel a drug liquid from said drug reservoir to a dispenser module that comprises a predetermined number of drug delivery openings for delivering a drug, received from said drug reservoir, to tissue.

Claims

1. Implantable catheterless drug delivery system comprising:

a reservoir module provided with a drug reservoir; and

a drug expelling means arranged to expel a drug liquid from said drug reservoir to a catheterless dispenser module,

said catheterless dispenser module comprising a predetermined number of drug delivery openings for delivering a drug, received from said drug reservoir, to tissue, wherein said predetermined number is at least two.

2. System according to claim 1 wherein the openings of the dispenser module are arranged on the part of the catheterless dispenser module adapted to be in contact with tissue.

3. System according to claim 1 wherein the openings of the catheterless dispenser module are arranged along the periphery of the catheterless dispenser module.

4. System according to claim 1 characterized in that said predetermined number of delivery openings is four.

5. System according to claim 1 characterized in that said predetermined number of delivery openings lies in the interval 10-30.

6. System according to claim 1 wherein said reservoir module comprises drug supplying means adapted to be coupled to the catheterless dispenser module in order to supply the catheterless dispenser module with the drug from the reservoir module.

7. System according to claim 1 wherein said modules are physically separate parts and that said reservoir module is provided with a first connecting means and said catheterless dispenser module is provided with a second connecting means, wherein, at the time of implantation, said reservoir and catheterless dispenser modules are adapted to be connected together by said first and second connecting means.

8. System according to claim 1 characterized in that said delivery opening comprises an outflow opening (36) and protecting means (35) wherein said outflow opening 36 is protected against direct pressure from the tissue by said protective means.

9. System according to claim 8 characterized in that said protecting means (35) comprises a rounded end of plate.

10. An implantable drug delivery system comprising:

a dispenser module; and

a reservoir module,

wherein the reservoir module comprises a drug reservoir having a reservoir opening, a drug delivery device inside said opening, said drug delivery device includes a centrally located externally threaded male nipple, a drug expelling device adjacent to said opening and a first protective casing enclosing the reservoir and the expelling device, and

wherein the dispenser module comprises a centrally located internally threaded female connecting nipple for threadedly engaging said male nipple, a plurality of delivery openings and a plurality of delivery channels delivering a drug from the reservoir to the plurality of delivery openings.

11. The implantable drug delivery system according to claim 10, wherein the drug reservoir is compressible and elastic.

12. The implantable drug delivery system according to claim 10, wherein the drug expelling device comprises a plurality of movable parallel plates outside the drug reservoir and a plurality of elastic devices between the plates and a wall of the first protective casing for providing a mechanical force on the plates.

13. The implantable drug delivery system according to claim 12, wherein the elastic devices are at least one of helix-wound springs and spring leaves.

14. The implantable drug delivery system according to claim 10, wherein the dispenser module and the reservoir module are integrated into one unit and further comprising a second protective casing enclosing both the reservoir module and the dispenser module.

15. The implantable drug delivery system according to claim 10, wherein the dispenser module and the reservoir module are essential mirror images of each other.

16. An implantable drug delivery system comprising:

an arcuate-shaped dispenser module having an arcuate portion and a planar portion; and

an arcuate-shaped reservoir module having an arcuate portion and a planar portion,

wherein the reservoir module comprises an externally threaded male nipple extending from the planar portion of the reservoir module, and

wherein the dispenser module comprises an internally threaded female connecting nipple extending from the planar portion of the dispenser module for threadedly engaging said male nipple, at least two drug delivery openings and a plurality of delivery channels delivering a drug from the reservoir module to the at least two drug delivery openings.

17. The implantable drug delivery system according to claim 16, wherein each of the plurality of delivery channels comprise two parallel delivery sections with a delivery channel therebetween terminating in an outflow opening, a first one of said two parallel sections having an end portion bending around a second one of said two parallel sections for protecting the outflow opening against pressure from surrounding tissue.

18. The implantable drug delivery system according to claim 17, wherein the outflow opening is at a peak of the end portion to prevent accumulation of drug fluid at the outflow opening.