Method for localized low energy photon therapy (LEPT)

• US 6,494,900 B1
• Filed: 01/31/2000
• Issued: 12/17/2002
• Est. Priority Date: 01/06/1997
• Status: Expired due to Term

• Current Assignee: International Medical Instruments Incorporated
• Original Assignee: International Medical Instruments Incorporated
• Inventors: Salansky, Norman, Filonenko, Natalia
• Primary Examiner(s): Kearney, Rosiland S.
• Application Number:
  US09/494,659
• Time in Patent Office: 1,051 Days
• Field of Search: 606/2, 606/9-12, 606/13, 607/88, 607/89, 128/898
• US Class Current: 607/89
• CPC Class Codes: A61N 2005/0645 Applicators worn by the patient
• CPC Class Codes: A61N 2005/0652 Arrays of diodes
• CPC Class Codes: A61N 5/0616 Skin treatment other than tanning
• CPC Class Codes: A61N 5/0624 for eliminating microbes, germs, bacteria on or in the body

Abstract

Novel apparatus for treating a disorder of a biological tissue in a mammal by stimulating the biological tissue with light having selected optical parameters. The apparatus has a power source, a central microprocessor with stored optical parameter protocols and wireless probes to receive the protocols and to generate and transmit the light. The invention also relates to a method for stimulating healing of a disorder of a biological tissue in a mammal by stimulating the biological tissue with light having selected optical parameters.

Claims

1. A method for stimulating healing of a dermatological, musculoskeletal, soft tissue or neurological disorder of a biological tissue in a mammal by stimulating the biological tissue with low energy light having selected optical parameters, comprising:

(a) providing a central microprocessor having stored optical parameter protocols suitable for treating a range of disorders of biological tissue, said parameters including wavelength, power, intensity and dose;

(b) selecting a stored optical parameter protocol for the disorder to be treated; and

(c) providing an array of light emitting sources, all of said sources when activated producing substantially monochromatic non-ionizing light having a selected wavelength in the range of from 630 to 2000 nm and a bandwidth not exceeding substantially 30 to 40 nm, and each of said sources providing light of the same said selected wavelength;

(d) activating selected ones of said light emitting sources to produce a desired three dimensional light distribution at said tissue according to the selected optical parameter protocol; and

(e) directing the beam of light to the biological tissue to be treated.

2. A method of stimulating healing of a lesion in a mammal, comprising:

irradiating the lesion with a beam of light using an array of light emitting sources, selected ones of said light emitting sources being activated to produce a desired three dimensional light distribution at said lesion, all of said sources when activated producing substantially monochromatic non-ionizing light having a selected wavelength in the range of from 630 to 2000 nm and a bandwidth not exceeding substantially 30 to 40 nm, and each of said sources providing light of the same said selected wavelength and no other wavelength, said beam of light having predetermined optical parameters, wherein the predetermined optical parameters include a dose of from 0.05 to 25 J/cm², an intensity of from 0.2 to 5000 mW/cm², a continuous wave mode or a pulse repetition rate of from 0 to 200 Hz, and optional modulation frequencies of said continuous wave mode or of said pulse repetition rate of any of from 0.2 to 0.3 Hz, 1 to 1.2 Hz, and 1 to 5 Hz.

3. The method of claim 2 wherein the lesion is an ulcer or a wound and the selected optical parameters include a dose of from 0.05 to 0.2 J/cm², a wavelength of from 600 to 700 nm, a continuous wave mode or pulse repetition rate of from 0 to 200 Hz, and optional modulation frequencies of said continuous wave mode or of said pulse repetition rate of any of from 0.2 to 0.3 Hz, 1 to 1.2 Hz, and 1 to 5 Hz.

4. The method of claim 2 wherein the lesion is an ulcer or wound in acute inflammatory condition and the selected optical parameters include a dose of from 2.0 to 5.0 J/cm², an intensity of from 10.0 to 30 mW/cm², and a wavelength of from 600 to 700 nm, a continuous wave mode or pulse repetition rate of from 0 to 200 Hz, and optional modulation frequencies of said continuous wave mode or of said pulse repetition rate of any of from 0.2 to 0.3 Hz., 1 to 1.2 Hz, and 1 to 5 Hz.

5. The method of claim 2 wherein the lesion is an infected wound and the selected optical parameters include a dose of from 3.0 to 9.0 J/cm², an intensity of from 50.0 to 80 mW/cm² and a wavelength of from 600 to 700 nm, a continuous wave mode or pulse repetition rate of from 0 to 200 Hz, and optional modulation frequencies of said continuous wave mode or of said pulse repetition rate of any of from 0.2 to 0.3 Hz, 1 to 1.2 Hz, and 1 to 5 Hz.

6. The method of claim 2 wherein the lesion is an ulcer or a wound in the area with impaired microcirculation and the selected optical parameters include a dose of from 0.1 to 9.0 J/cm², an intensity of from 300 to 600 mW/cm² and a wavelength of from 800 to 1,100 nm in a continuous wave (CW) mode or with pulse repetition rate of 10 Hz or from 50 to 200 Hz, and optional modulation frequencies of said continuous wave mode or of said pulse repetition rate of any of 0.3 and/or 1.2 Hz and the area to be treated is the skin surrounding the lesion.

7. The method of claim 2 where the lesion is an ulcer or wound and the selected optical parameters include a suitable combination of one or more of the following optical parameters:

(a) a dose of from 0.05 to 0.2 J/cm², a wavelength of from 600 to 700 nm, a continuous wave mode or pulse repetition rate of from 0 to 200 Hz, and optional modulation frequencies of said continuous wave mode or of said pulse repetition rate of any of from 0.2 to 0.3 Hz, 1 to 1.2 Hz, and 1 to 5 Hz;

(b) a dose of from 2.0 to 5.0 J/cm ², an intensity of from 10.0 to 30 mW/cm², and a wavelength of from 600 to 700 nm, a continuous wave mode or pulse repetition rate of from 0 to 200 Hz, and optional modulation frequencies of said continuous wave mode or of said pulse repetition rate of any of from 0.2 to 0.3 Hz, 1 to 1.2 Hz, and 1 to 5 Hz;

(c) a dose of from 3.0 to 9.0 J/cm², an intensity of from 50.0 to 80 mW/cm² and a wavelength of from 600 to 700 nm, a continuous wave mode or pulse repetition rate of from 0 to 200 Hz, and optional modulation frequencies of said continuous wave mode or of said pulse repetition rate of any of from 0.2 to 0.3 Hz, 1 to 1.2 Hz, and 1 to 5 Hz; and

(d) a dose of from 0.1 to 9.0 J/cm², an intensity of from 300 to 600 mW/cm² and a wavelength of from 800 to 1,100 nm in a continuous wave (CW) mode or with pulse repetition rate of 10 Hz or from 50 to 200 Hz, and optional modulation frequencies of said continuous wave mode or of said pulse repetition rate of any of 0.3 and/or 1.2 Hz;

wherein the suitable combination depends on the ulcer or wound condition or stage.

8. The method of claim 2 wherein the lesion is a post-surgical scar in an acute inflammatory condition and the selected optical parameters include a dose of from 2 to 5 J/cm², an intensity of from 10 to 30 mW/cm² and a wavelength of from 600 to 700 nm.

9. The method of claim 2 wherein the lesion is a post-surgical scar in a sub-acute inflammatory condition and the selected optical parameters include a dose of from 3 to 7 J/cm² or 4 to 25 J/cm², an intensity of from 10 to 40 mW/cm² or 60 to 100 mW/cm² or 300-600 mW/cm² or 1000 to 5000 mW/cm² and a wavelength of from 800 to 1100 nm.

10. The method of claim 2 wherein the lesion is induced by Herpes Simplex virus (cold sore) or acne and the selected optical parameters include a dose of from 4 to 9 J/cm², an intensity of from 20 to 60 mW/cm² and a wavelength of from 630 to 700 nm.