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Compositions containing lysophosphotidic acids which inhibit apoptosis and uses thereof

  • US 6,495,532 B1
  • Filed: 02/28/2000
  • Issued: 12/17/2002
  • Est. Priority Date: 03/19/1997
  • Status: Expired due to Fees
First Claim
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1. A composition comprising a therapeutically effective amount of an LPA selected from the group consisting ofOleyl 1-thiophosphoryl-2-O-Methyl-rac-glycerate, 1-(3-propyl oleoate)thiophosphate, 3-O-Oleoyl-2-O-methyl-rac-glycero-1-thiophosphate, 3-O-Oleyl-2-O-methyl-rac-glycero-1-thiophosphate, 3-O-Oleyl-2-O-methyl-rac-glycero-1-phosphate, 3-O-Oleyl-rac-glycero-1-phosphate, 3-O-Oleyloxypropyl-1-phosphate and 1-(3-propyl oleoate)phosphate and a potentiating component in an amount sufficient to potentiate the therapeutic effectiveness of the LPA.

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