Dual frequency microwave heating apparatus

• US 6,496,738 B2
• Filed: 02/06/2001
• Issued: 12/17/2002
• Est. Priority Date: 09/06/1995
• Status: Expired due to Term

• Current Assignee: Coral Sand Beach, LLC
• Original Assignee: Microwave Medical Systems Incorporated (General Electric Company)
• Inventors: Carr, Kenneth L.
• Primary Examiner(s): GIBSON, ROY DEAN
• Application Number:
  US09/777,971
• Publication Number:
  US 20010016762A1
• Time in Patent Office: 679 Days
• Field of Search: 607/96, 607/98-102, 607/105, 604/113, 604/114
• US Class Current: 607/101
• CPC Class Codes: A61B 18/18 by applying electromagnetic radiation, e.g. microwaves radiation therapy A61N5/00
• CPC Class Codes: A61B 18/1815 using microwaves
• CPC Class Codes: A61B 2018/1861 with an instrument inserted into a body lumen or cavity, e.g. a catheter
• CPC Class Codes: A61F 2007/126 for invasive application, e.g. for introducing into blood vessels
• CPC Class Codes: A61M 1/0281 Apparatus for treatment of blood or blood constituents prior to transfusion, e.g. washing, filtering or thawing
• CPC Class Codes: A61M 1/3623 Means for actively controlling temperature of blood
• CPC Class Codes: A61M 1/369 Temperature treatment
• CPC Class Codes: A61M 2205/3686 microwaves
• CPC Class Codes: A61M 5/44 having means for cooling or heating the devices or media
• CPC Class Codes: H05B 6/802 for heating fluids methods of heating fluids in conventional microwave ovens H05B6/687

Abstract

Microwave heating apparatus for heating fluid or tissue includes an elongated catheter for placement adjacent to high/dielectric high loss organic fluid or tissue in a patient. The catheter has a distal end and a proximal end and includes an antenna adjacent to the distal end and a cable having one end connected to the antenna and a second end. A transmitter provides a transmitter signal capable of heating the fluid or tissue and a first receiver receives a first signal indicative of thermal radiation from a first depth in the fluid or tissue, producing a first output signal in response thereto. There is also a second receiver for receiving a second signal indicative of thermal radiation from a second depth in the fluid or tissue, producing a second output signal in and response thereto. The apparatus also includes active and passive diplexers connected in series between the transmitter and the second end of the cable. A controller controls the active diplexer so that when the transmitter is transmitting, the first signal is coupled to the passive diplexer but not to the second receiver and when the transmitter is not transmitting, a second signal from the passive diplexer is coupled to the second receiver but not to the transmitter. During operation of the apparatus, the passive diplexer couples the transmitter signal only to the antenna while coupling a first signal from the antenna only to the first receiver so that the apparatus can heat the fluid or tissue and determine the actual temperatures of the fluid or tissue at two different depths.

Claims

1. Microwave heating apparatus for heating fluid or tissue, said apparatus comprising

an elongated catheter for placement adjacent to high dielectric/high loss organic fluid or tissue in a patient, said catheter having a distal end and a proximal end and including an antenna adjacent to said distal end and a cable having one end connected to said antenna and a second end;

a transmitter for producing a transmitter signal capable of heating said fluid or tissue;

a first receiver for receiving a first signal having a first frequency indicative of thermal radiation from a first depth in said fluid or tissue and producing a first output signal in response thereto;

a second receiver for receiving a second signal having a second frequency indicative of thermal radiation from a second depth in said fluid or tissue and producing a second output signal in response thereto;

active and passive diplexers connected in series between said transmitter and the second end of said cable, said active diplexer including switch means operable between the transmitter, the passive diplexer and the second receiver;

control means for controlling the switch means so that when the transmitter is transmitting, the transmitter signal is coupled to the passive diplexer but not to the second receiver and when the transmitter is not transmitting, any second signal from the passive diplexer is coupled to the second receiver but not to the transmitter, said passive diplexer coupling said transmitter signal received via the active diplexer only to said antenna, while coupling a first signal received from the antenna only to the first receiver so that the apparatus can heat said fluid or tissue and determine the actual temperature of the fluid or tissue at two different depths.

2. The apparatus defined in claim 1 wherein said first and second receivers comprise first and second radiometers.

3. The apparatus defined in claim 2 wherein said antenna is a monopole.

4. The apparatus defined in claim 1 wherein said transmitter signal has a lower frequency than said first signal.

5. The apparatus defined in claim 4 wherein the second signal has the same frequency as the transmitter signal.

6. The apparatus defined in claim 5 wherein the transmitter signal and the second signal have a frequency of about 915 MHz and the first signal has a frequency of about 4 GHz.

7. The apparatus defined in claim 1 wherein said passive diplexer comprises

a first arm connected between the active diplexer and the cable second end and containing a low pass filter which passes only said transmitter signal, and

a second arm connected between the first receiver and a junction between the low pass filter and the cable second end, said second arm containing a band pass filter which passes said first signal but blocks said transmitter signal.

8. The apparatus defined in claim 7 wherein the length of the connection between the low pass filter and the junction is ¼

wavelength at the frequency of the first signal and the length of the connection between the band pass filter and the junction is ¼

wavelength at the frequency of the transmitter signal.

9. The apparatus defined in claim 1 and further including a display responsive to said first and second output signals for producing indications of the actual temperatures of said fluid or tissue at said different depths.

10. The apparatus defined in claim 1 and further including control means responsive to at least one of said first and second output signals for controlling the transmitter to heat said tissue according to a selected temperature/time profile.

11. Microwave heating apparatus for heating fluid or tissue, said apparatus comprising an

elongated catheter for placement adjacent to high/dielectric high loss organic fluid or tissue in a patient, said catheter having a distal end and a proximal end and including an antenna adjacent to said distal end and a cable having one end connected to said antenna and a second end;

a first receiver for receiving a first signal having a first frequency indicative of thermal radiation from a selected first depth in said fluid or tissue, and producing a first output signal in response thereto;

a passive diplexer connected between the second end of said cable and said first receiver, said passive diplexer having an input terminal;

a second receiver for receiving a second signal having a second frequency indicative of thermal radiation from a selected second depth in said fluid or tissue and producing a second output signal in response thereto;

a transmitter for producing a transmitter signal at a frequency capable of heating said fluid or tissue;

an active diplexer including switch means for selectively connecting the input terminal of the passive diplexer alternatively to the transmitter or to the second receiver, and

means for controlling the switch means so that when the transmitter is transmitting, the transmitter signal is coupled to the passive diplexer but not to the second receiver and when the transmitter is not transmitting, a second signal from the antenna is coupled to the second receiver but not to the transmitter, said passive diplexer coupling said transmitter signal from the transmitter only to said antenna while coupling a first signal from said antenna only to said first receiver so that the apparatus can simultaneously heat said fluid or tissue and determine the actual temperature of said fluid or tissue at said first and second depths.

12. The apparatus defined in claim 11 wherein said first and second receivers comprise first and second radiometers.

13. The apparatus defined in claim 11 wherein said active diplexer comprises

a first SPST switch connected between the input of the active diplexer and the transmitter, and

a second SPST switch connected between the input terminal of the passive diplexer and the second receiver, said switches being controlled by the controlling means.

14. The apparatus defined in claim 13 wherein the length of the connections between the input of the passive diplexer and each of said switches is ¼

wavelength at the frequency of the transmitter signal.

15. The apparatus defined in claim 11 wherein said active diplexer comprises an SPDT switch for connecting the input terminal of the passive diplexer alternatively to the transmitter or to the second receiver, said switch being controlling by the control means.