Coated superelastic stent

• US 6,497,671 B2
• Filed: 02/28/2001
• Issued: 12/24/2002
• Est. Priority Date: 12/05/1997
• Status: Expired due to Term

• Current Assignee: Micrus Corporation (Johnson & Johnson)
• Original Assignee: Micrus Corporation (Johnson & Johnson)
• Inventors: Wilson, Peter, Ferrera, David A.
• Primary Examiner(s): Hindenburg, Max
• Assistant Examiner(s): Marmor, II, Charles A.
• Application Number:
  US09/797,365
• Publication Number:
  US 20010009982A1
• Time in Patent Office: 664 Days
• Field of Search: 600/434, 600/435, 600/585, 623/1.1, 623/1.12, 623/1.13, 623/1.15, 623/1.18, 623/1.22, 623/1.34, 623/1.42, 623/1.45, 623/1.47, 604/104, 606/191, 606/194
• US Class Current: 600/585
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/12145 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/1215 comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
• CPC Class Codes: A61B 2017/12072 the heat created by laser light
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers
• CPC Class Codes: A61L 2400/16 Materials with shape-memory or superelastic properties
• CPC Class Codes: A61L 31/044 Collagen
• CPC Class Codes: A61L 31/128 containing other specific inorganic fillers not covered by A61L31/126 or A61L31/127
• CPC Class Codes: A61L 31/14 Materials characterised by their function or physical properties , e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
• CPC Class Codes: A61L 31/18 Materials at least partially X-ray or laser opaque
• CPC Class Codes: A61M 2025/09191 made of twisted wires

Abstract

The coated superelastic stent is formed from a tube of collagen having an inner structure of a micro-cable made of strands of a material exhibiting super-elasticity or shape memory properties, such as nickel-titanium, and includes a strand of radiopaque material, such as platinum or gold, in order to provide a radiopaque marker during interventional therapeutic treatment or vascular surgery. The collagen tube can be loaded with a therapeutic agent for treatment of the desired site in the vasculature.

Claims

1. A collagen coated stent for use in interventional therapy and vascular surgery, comprising in combination:

a collagen tube; and

at least one flexible strand of shape memory material disposed within said collagen tube, and wherein said combination of said collagen tube and said at least one flexible strand of shape memory material forms a ribbon forming the structure of said stent.

2. The collagen coated stent of claim 1, wherein said ribbon is configured to have a helical shape.

3. The collagen coated stent of claim 1, wherein said at least one flexible strand of shape memory material has a sinusoidal shape.

4. The collagen coated stent of claim 1, wherein said at least one flexible strand of shape memory material further comprises an axially disposed radiopaque strand.

5. The collagen coated stent of claim 4, wherein said at least one flexible strand of shape memory material comprises a plurality of flexible strands of shape memory material twisted about said axially disposed radiopaque strand.

6. The collagen coated stent of claim 5, wherein said radiopaque strand comprises a platinum strand.

7. The collagen coated stent of claim 5, wherein said radiopaque strand comprises a gold strand.

8. The collagen coated stent of claim 5, wherein said radiopaque strand comprises a tungsten strand.

9. The collagen coated stent of claim 1, wherein said at least one flexible strand of shape memory material is comprised of a super-elastic material.

10. The collagen coated stent of claim 9, wherein said super-elastic material comprises a nickel titanium alloy.

11. The collagen coated stent of claim 1, wherein said shape memory material comprises a nickel-titanium alloy.

12. The collagen coated stent of claim 1, wherein said shape memory material comprises a shape memory polymer.

13. The collagen coated stent of claim 1, wherein said collagen tube is loaded with a therapeutic agent.

14. A collagen coated stent for use in interventional therapy and vascular surgery, comprising in combination:

a collagen tube;

at least one flexible strand of shape memory material; and

a sheath to constrain said at least one flexible strand of shape memory material about a longitudinal axis;

wherein

said at least one flexible strand of shape memory material and said sheath are disposed within said collagen tube, and wherein said combination of said collagen tube, said at least one flexible strand of shape memory material, and said sheath forms a ribbon forming the structure of said stent.

15. The collagen coated stent of claim 14, wherein said at least one flexible strand of shape memory material comprises a super-elastic material.

16. The collagen coated stent of claim 15, wherein said super-elastic material comprises a nickel titanium alloy.

17. The collagen coated stent of claim 14, wherein said shape memory material comprises a nickel titanium alloy.

18. The collagen coated stent of claim 14, wherein said at least one flexible strand comprises a plurality of longitudinal strands, and said sheath comprises a containment strand wound about said longitudinal strands.

19. The collagen coated stent of claim 14, further comprising an outer flexible sheath of low friction material.

20. The collagen coated stent of claim 14, wherein said sheath comprises a heat shrinkble plastic tube.

21. The collagen coated stent of claim 14, further comprising a radiopaque strand.

22. The collagen coated stent of claim 21, wherein said radiopaque strand comprises a platinum strand.

23. The collagen coated stent of claim 21, wherein said radiopaque strand comprises a gold strand.

24. The collagen coated stent of claim 21, wherein said radiopaque strand comprises a tungsten strand.

25. The collagen coated stent of claim 14, wherein said shape memory material comprises a shape memory polymer.