Electrical impedance tomography method and electrode arrangement for use therein

• US 6,501,984 B1
• Filed: 05/20/1999
• Issued: 12/31/2002
• Est. Priority Date: 11/26/1996
• Status: Expired due to Fees

• Current Assignee: General Dynamics Canada Limited (General Dynamics Corporation)
• Original Assignee: Computing Devices Canada Ltd. (General Dynamics Corporation)
• Inventors: Church, Philip M., Wort, Philip M.
• Primary Examiner(s): MANUEL, GEORGE C
• Application Number:
  US09/308,521
• Time in Patent Office: 1,321 Days
• Field of Search: 600/547, 600/407, 600/393, 324/600, 324/603, 324/605, 324/609, 324/629
• US Class Current: 600/547
• CPC Class Codes: A61B 5/0536 Impedance imaging, e.g. by tomography

Abstract

An electrode arrangement for an electrical impedance tomography system comprises a plurality of electrodes in an array mounted in a support medium for supporting the electrodes adjacent a surface of a volume the electrical conductivity distribution of which is to be measured, for example the thorax or another body part, a pipeline, the ground, and so on. The electrodes are disposed in two groups, the arrangement being such that, in use, one group will be closer to the surface than the other group, In operation, applying a known current to them. For each stimulated pair, a resulting potential difference will be recorded at the pair of the remaining electrodes which, if stimulated, would produce an electric field with vectors of the electric field produced by the stimulated pair of electrodes.

Claims

1. A method of determining electrical impedance tomography of a conductive volume (12) comprising the steps of selecting, in turn, each of a plurality of pairs of locations (S) upon a surface of the volume (12) and supplying a stimulation current to the surface by way of the selected pair of locations, and recording, for each selected pair, a resulting potential difference between at least one pair (R) of the remaining locations, and processing the recorded potential differences to plot electrical conductivity distribution within said volume, and, for a particular pair of locations stimulated, selecting from among the remaining locations, for recordal, the pair or pairs of locations which, if stimulated, would produce an electric field with vectors most closely aligned with the corresponding vectors of the electric field produced by stimulation of said particular pair of locations, and recording said potential difference at the said pair or pairs of locations so selected for recordal.

2. A method of determining electrical impedance tomography according to claim 1, using a plurality of electrodes (S₁-S₁₆, R₁-R₁₆) disposed upon or adjacent said surface each at a respective one of said plurality of locations, comprising the steps of;

(i) applying a stimulation current to said volume by way of a first (S₁) and a second (S₂) of said plurality of electrodes at corresponding first and second locations;

(ii) simultaneously recording the resulting potential difference between that pair (R₁, R₂) of the remaining electrodes at said pair of locations which, if stimulated, would produce electric field vectors most closely aligned with the electric field vectors produced by stimulation of said particular pair of locations;

(iii) applying a stimulation current to said body by way of two electrodes (S₂, S₃) at least one of which was not stimulated in a previous step;

(iv) simultaneously recording the resulting potential difference between that pair (R₂, R₃) of the remaining electrodes at said locations which, if stimulated, would produce an electric field with vectors most closely aligned with the corresponding vectors of the electric field produced by the stimulation current applied in step (iii).

3. A method according to claim 2, wherein stimulation current is applied to a said first and second of said plurality of electrodes with no intervening electrodes.

4. A method according to claim 2, wherein said stimulation current is applied to a said first and second of said plurality of electrodes that are spaced apart with one or more other electrodes therebetween.

5. A method according to claim 4, wherein each performance of steps (iii) and (iv) applies said stimulation current to a pair of electrodes that are spaced apart with a different number of intervening electrodes therebetween.

6. A method according to claim 2, wherein, in said steps (i) and (ii), said stimulation current is applied to a said first and second of said electrodes that have no electrodes therebetween, and said potential difference recorded, and, in said steps (iii) and (iv), a stimulation current is applied to a said two electrodes that have one or more electrodes therebetween, and the resulting potential difference recorded.

7. A method according to claim 2, wherein the stimulating currents are applied to selected pairs of a first group (S₁-S₁₆) of the plurality of electrodes and the resulting potential differences are recorded at selected pairs of a second group (R₁-R₁₆) of the plurality of electrodes, the electrodes (R₁-R₁₆) of one of the groups are closer to the surface than the electrodes (S₁-S₁₆) of the other of the groups.

8. A method according to claim 7, wherein each electrode of the first group is substantially aligned with a corresponding electrode of the second group in a direction extending substantially normal to said surface and said potential difference is recorded between that pair of said electrodes which are aligned with the pair of electrodes to which the stimulation current is applied.

9. A method according to claim 2, wherein each electrode means comprises a stimulation electrode (46) and a recording electrode (48) closely located to each other and both the same distance from said surface, the step of applying stimulation current applies the stimulation current to the stimulation electrodes (46) of two electrode means, respectively, and the corresponding potential difference is measured between the recording electrodes (48) of the same two electrode means.

10. A method according to claim 9, wherein one of the stimulating electrode (46) and the recording electrode (48) surrounds the other.

11. An electrode arrangement for an electrical impedance tomography system comprising a first group of electrodes (R₁-R₁₆) and a second group of electrodes (S₁-S₁₆) and support means (24,26,28,30) for supporting the electrodes adjacent a surface of a volume (12′

) the electrical impedance of which is to be mapped by the system, wherein the first group of electrodes (R₁-R₁₆) is closer than the second group of electrodes (S₁-S₁₆) to a part of the support means which, in use, will be adjacent said surface.

12. An electrode arrangement according to claim 11, each electrode of the first group (R₁-R₁₆) is substantially aligned with an adjacent electrode of the second group (S₁-S₁₆) in a direction extending substantially normal, in use, to said surface.

13. An electrode arrangement according to claim 12, wherein the support means (24,26,28,30) comprises an annular structure, the first group of electrodes (R₁-R₁₆) and the second group of electrodes (S₁-S₁₆) being arranged in an inner ring and an outer ring, respectively, about a central part of the annular structure.

14. An electrode arrangement according to claim 13, wherein the annular structure (24,26,28,30) is circular and the spacing between the inner ring of electrodes and the outer ring of electrodes is about one quarter of the diameter of the inner ring.

15. An electrode arrangement according to claim 11, wherein the support means (24,26,28,30) comprises an annular structure, the first group of electrodes (R₁-R₁₆) and the second group of electrodes (S₁-S₁₆) being arranged in an inner ring and an outer ring, respectively, about a central part of the annular structure.

16. An electrode arrangement according to claim 15, the annular structure (24,26,28,30) is circular and the spacing between the inner ring of electrodes and the outer ring of electrodes is about one quarter of the diameter of the inner ring.

17. An electrode arrangement according to claim 11, wherein the support means comprises a plurality of compartments (32₁-32₁₆), each comprising a conductive medium for contacting the surface of a volume (12′

) to be imaged, and lower conductivity partitions (28₁-28₁₆) between adjacent compartments, each compartment housing a pair of electrodes comprising one electrode from said first group (S₁-S₁₆) and one electrode from said second group (R₁-R₁₆).

18. An electrode arrangement according to claim 17, wherein the electrodes are supported in a planar array (60,62), and each electrode of said first group is spaced from an associated electrode of said second group in a direction substantially perpendicular to the plane of the array.

19. An electrode arrangement according to claim 11, wherein the support means (24,26,28,30) is rigid and a conductive interface medium (36) is disposed for juxtaposing between an inner surface of said support means and the surface of the volume (12) to be measured, the interface medium comprising a material that is conformable to contour variations of said surface of the volume.

20. An electrode arrangement according to claim 19, wherein the interface medium material (36) has a conductivity comparable to that of the volume to be measured.

21. An electrode arrangement according to claim 19, wherein each electrode of the first group (R₁-R₁₆) is substantially aligned with an adjacent electrode of the second group (S₁-S₁₆) in a direction extending substantially normal, in use, to said surface.

22. An electrode arrangement according to claim 19, wherein the support means (24,26,28,30) comprises an annular structure, the first group of electrodes (R₁-R₁₆) and the second group of electrodes (S₁-S₁₆) being arranged in an inner ring and an outer ring, respectively, about a central part of the annular structure.

23. An electrode arrangement according to claim 22, wherein the annular structure (24,26,28,30) is circular and the spacing between the inner ring of electrodes and the outer ring of electrodes is about one quarter of the diameter of the inner ring.

24. An electrode arrangement according to claim 19, wherein the support means comprises a plurality of compartments (32₁-32₁₆), each comprising a conductive medium for contacting the surface of a volume (12′

) to be imaged, and lower conductivity partitions (28₁-28₁₆) between adjacent compartments, each compartment housing a pair of electrodes comprising one electrode from said first group (S₁-S₁₆) and one electrode from said second group (R₁-R₁₆).

25. An electrode arrangement according to claim 24, wherein the interface medium material (36) has a conductivity comparable to that of the volume to be measured.

26. An electrode arrangement according to claim 19, wherein the electrodes are supported in a planar array (60,62), and each electrode of said first group is spaced from an associated electrode of said second group in a direction substantially perpendicular to the plane of the array.

27. An electrode arrangement according to claim 11, wherein the support means (24,26,28,30) has anisotropic conductivity with its conductivity in said direction normal to said surface, in use, being significantly higher than its conductivity in directions transverse thereto.

28. An electrode arrangement according to claim 27, wherein the support means (24,26,28,30) comprises a plurality of higher conductivity sectors (32) alternating with, and defined by, a plurality of lower conductivity regions (28).

29. An electrode arrangement according to claim 27, wherein each electrode of the first group (R₁-R₁₆) is substantially aligned with an adjacent electrode of the second group (S₁-S₁₆) in a direction extending substantially normal, in use, to said surface.

30. An electrode arrangement according to claim 27, wherein the support means (24,26,28,30) comprises an annular structure, the first group of electrodes (R₁-R₁₆) and the second group of electrodes (S₁-S₁₆) being arranged in an inner ring and an outer ring, respectively, about a central part of the annular structure.

31. An electrode arrangement according to claim 30, wherein the annular structure (24,26,28,30) is circular and the spacing between the inner ring of electrodes and the outer ring of electrodes is about one quarter of the diameter of the inner ring.

32. An electrode arrangement according to claim 27, wherein the support means comprises a plurality of compartments (32₁-32₁₆), each comprising a conductive medium for contacting the surface of a volume (12′

) to be imaged, and lower conductivity partitions (28₁-28₁₆) between adjacent compartments, each compartment housing a pair of electrodes comprising one electrode from said first group (S₁-S₁₆) and one electrode from said second group (R₁-R₁₆).

33. An electrode arrangement according to claim 27, wherein the electrodes are supported in a planar array (60,62), and each electrode of said first group is spaced from an associated electrode of said second group in a direction substantially perpendicular to the plane of the array.

34. An electrode arrangement according to claim 27, wherein the support means (24,26,28,30) is rigid and a conductive interface medium (36) is disposed for juxtaposing between an inner surface of said support means and the surface of the volume (12) to be measured, the interface medium comprising a material that is conformable to contour variations of said surface of the volume.

35. An electrode arrangement according to claim 34, wherein the interface medium material (36) has a conductivity comparable to that of the volume to be measured.

36. An electrode arrangement for an electrical impedance tomography system comprising a plurality of electrodes (S₁-S₁₆, R₁-R₁₆) in an array mounted in a support (24,26,28,30) for supporting the electrodes adjacent a surface of a volume (12′

) to be imaged, wherein the support comprises a plurality of low conductivity sections (28₁-28₁₆) alternating with a plurality of high conductivity sections (32₁-32₁₆) so that its conductivity in a direction that, in use, is normal to the surface is significantly greater than its conductivity in a transverse direction, and the electrodes (R₁-R₁₆, S₁-S₁₆) are disposed in the high conductivity sections (32₁-32₁₆), respectively, so as to be spaced, in use, from said surface.

37. An electrode arrangement according to claim 36, wherein the support comprises a plurality of compartments (32₁-32₁₆), each separated from neighbouring compartments by an insulating partition (28₁-28₁₆), each compartment comprising a material having a conductivity comparable to the conductivity of the volume the conductivity distribution of which is to be measured and containing at least one of the electrodes.

38. An electrode arrangement for an electrical impedance tomography system comprising an array of electrodes (S₁-S₁₆, R₁-R₁₆) fixed spatially relative to each other in a rigid support (24,26,28,30), and an interface medium (36) for interfacing the rigid support to a surface of a volume (12′

) the conductivity distribution of which is to be measured, the interface medium being conductive so as to connect the electrodes electrically to the surface and pliable so as to conform to variations in relief of the surface.

39. An electrode arrangement according to claim 38, wherein the interface medium material (36) has a conductivity comparable to that of the volume to be measured.

40. An electrical impedance tomograph according to claim 39, wherein the support means comprises a plurality of compartments (32₁-32₁₆), each comprising a conductive medium for contacting the surface of a volume (12′

) to be imaged, and lower conductivity partitions (28₁-28₁₆) between adjacent compartments, each compartment housing a pair of electrodes comprising one electrode from said first group (S₁-S₁₆) and one electrode from said second group (R₁-R₁₆).

41. An electrical impedance tomograph comprising a first group of electrodes (R_1-R16) and a second group of electrodes (S₁-S₁₆) and support means (24,26,28,30) for supporting the electrodes adjacent a surface of a volume (12′

) the electrical impedance of which is to be mapped by the system, wherein the first group of electrodes (R₁-R₁₆) is closer than the second group of electrodes (S₁-S₁₆) to a part of the support means which, in use, will be adjacent said surface, and further comprising means (16,18,20) for stimulating, sequentially, pairs of electrodes (S₁-S₁₆) and, for each pair stimulated, measuring corresponding potential differences between a pair or pairs of the remaining electrodes, and processing the measured potentials to map electrical conductivity distribution of a volume (12′

).

42. An electrical impedance tomograph according to claim 41, wherein each electrode of the first group (R₁-R₁₆) is substantially aligned with an adjacent electrode of the second group (S₁-S₁₆) in a direction extending substantially normal, in use, to said surface.

43. An electrical impedance tomograph according to claim 42, wherein the support means (24,26,28,30) comprises an annular structure, the first group of electrodes (R₁-R₁₆) and the second group of electrodes (S₁-S₁₆) being arranged in an inner ring and an outer ring, respectively, about a central part of the annular structure.

44. An electrical impedance tomograph according to claim 43, wherein the annular structure (24,26,28,30) is circular and the spacing between the inner ring of electrodes and the outer ring of electrodes is about one quarter of the diameter of the inner ring.

45. An electrical impedance tomograph according to claim 41, wherein the support means (24,26,28,30) comprises an annular structure, the first group of electrodes (R₁-R₁₆) and the second group of electrodes (S₁-S₁₆) being arranged in an inner ring and an outer ring, respectively, about a central part of the annular structure.

46. An electrical impedance tomograph according to claim 41, wherein the electrodes are supported in a planar array (60,62), and each electrode of said first group is spaced from an associated electrode of said second group in a direction substantially perpendicular to the plane of the array.

47. An electrical impedance tomograph according to claim 41, wherein the support means (24,26,28,30) is rigid and a conductive interface medium (36) is disposed for juxtaposing between an inner surface of said support means and the surface of the volume (12) to be measured, the interface medium comprising a material that is conformable to contour variations of said surface of the volume.

48. An electrical impedance tomograph according to claim 47, wherein the interface medium material (36) has a conductivity comparable to that of the volume to be measured.

49. An electrical impedance tomograph according to claim 41, wherein the support means (24,26,28,30) has anisotropic conductivity with its conductivity in said direction normal to said surface, in use, being significantly higher than its conductivity in directions transverse thereto.

50. An electrode impedance tomograph according to claim 49, wherein the support means (24,26,28,30) comprises a plurality of higher conductivity sectors (32) alternating with, and defined by, a plurality of lower conductivity regions (28).

51. An electrical impedance tomograph according to claim 41, wherein the support comprises a plurality of low conductivity sections (28₁-28₁₆) alternating with a plurality of high conductivity sections (32₁-32₁₆) so that its conductivity in a direction that, in use, is normal to the surface is significantly greater than its conductivity in a transverse direction, and the electrodes (R₁-R₁₆, S₁-S₁₆) are disposed in the high conductivity sections (32₁-32₁₆), respectively, so as to be spaced, in use, from said surface.

52. An electrical impedance tomograph according to claim 51, wherein the support comprises a plurality of compartments (32₁-32₁₆), each separated from neighbouring compartments by an insulating partition (28₁-28₁₆), each compartment comprising a material having a conductivity comparable to the conductivity of the volume the conductivity distribution of which is to be measured and containing at least one of the electrodes.

53. An electrical impedance tomograph for use in a method of determining electrical impedance tomography of a conductive volume (12) by selecting, in turn, each of a plurality of pairs of locations (S) upon a surface of the volume (12) and supplying a stimulation current to the surface by way of the selected pair of locations, and recording, for each selected pair, a resulting potential difference between at least one pair (R) of the remaining locations, and processing the recorded potential differences to plot electrical conductivity distribution within said volume comprising:

(i) a plurality of electrodes (S₁-S₁₆, R₁-R₁₆) for disposing upon or adjacent said surface, each at a respective one of said plurality of locations;

(ii) means (16) for selecting each pair (S₁,S₂;

S₂,S₃, . . . S₁₅,S₁₆) of electrodes in turn and applying a stimulation current thereto and, for each particular pair of locations stimulated, the pair or pairs of locations which, if stimulated, would produce an electric field with vectors most closely aligned with the corresponding vectors of the electric field produced by stimulation of said particular pair of locations; and

recording the potential difference between each pair of electrodes selected for recordal; and

(iii) means (18) for processing the recorded potential differences to determine the electrical impedance tomography for the volume.