×

Human tumor necrosis factor receptor-like proteins TR11, TR11SV1 and TR11SV2

  • US 6,503,184 B1
  • Filed: 02/23/2000
  • Issued: 01/07/2003
  • Est. Priority Date: 10/21/1997
  • Status: Expired due to Fees
First Claim
Patent Images

1. A method of inhibiting binding of Endokine-alpha to endogenous Endokine-alpha receptors in a mammal comprising administering to said mammal an effective amount of TR11 polypeptide selected from the group consisting of:

  • (a) a polypeptide whose amino acid sequence comprises amino acid residues −

    25-137 of SEQ ID NO;

    2;

    (b) a polypeptide whose amino acid sequence comprises amino acid residues 1-137 of SEQ ID NO;

    2;

    (c) a polypeptide whose amino acid sequence comprises amino acid residues 1-114 SEQ ID NO;

    2; and

    (d) a polypeptide fragment of the polypeptide of SEQ ID NO;

    2, wherein said fragment binds endokine-alpha;

    in a pharmaceutically acceptable carrier.

View all claims
  • 1 Assignment
Timeline View
Assignment View
    ×
    ×