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Monomolecular adhesion methods for manufacturing microfabricated multilaminate devices

  • US 6,503,359 B2
  • Filed: 03/05/1999
  • Issued: 01/07/2003
  • Est. Priority Date: 03/05/1999
  • Status: Expired due to Fees
First Claim
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1. A method of providing one or more chemical reactants within a microfluidic channel or microfluidic chamber when attaching a first surface to a second surface to form such a microfluidic channel or microfluidic chamber located between said first and second surfaces, said method comprising:

  • contacting said first surface with said second surface, said first surface having a first bonding surface and a recessed surface defining a first channel or chamber wall and said second surface having a bonding surface and a recessed surface defining a second channel or chamber wall, said contacting including aligning said first wall and said second wall in registration therewith;

    a first reactant for a chemical bonding reaction being present on said first surface including said first bonding surface and said first wall, a second reactant for said chemical bonding reaction being present on said second surface including said second bonding surface and said second wall, and said surfaces being contacted for a time and under conditions sufficient to permit said chemical reaction to bond sufficient first reactant to said second reactant to attach said first bonding surface to said second bonding surface;

    said first and second walls forming a microfluidic channel or microfluidic chamber located between said first and second surfaces, said first reactant on said first wall and said second reactant on said second wall not undergoing said chemical bonding reaction.

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