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Nucleic acid ligand diagnostic biochip

  • US 6,503,715 B1
  • Filed: 11/28/2000
  • Issued: 01/07/2003
  • Est. Priority Date: 12/15/1997
  • Status: Expired due to Term
First Claim
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1. A diagnostic biochip for detection of a target molecule in a test mixture, the biochip comprising a solid support, said support comprising a plurality of spatially defined addresses, each said address having at least one copy of a single species of nucleic acid ligand attached thereto, each said species of nucleic acid ligand having specific affinity for one of said target molecules suspected of being contained in said test mixture, and each said species of nucleic acid ligand binding specifically to said target molecule through non-Watson-Crick interactions.

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