Dual chamber pacing system having time-adaptive AV delay
First Claim
1. A dual chamber pacing system adapted for pacing a heart in a patient during a post-implant Time-Adaptive period, comprising:
- atrial sense means for sensing an atrial signal from an atria of the patient'"'"'s heart and providing an A-EVENT signal;
AV delay timing means for timing an AV delay from an A-EVENT signal;
ventricular sense means for sensing a ventricular signal from ventricles of the patient'"'"'s heart and providing a V-EVENT signal;
ventricular pace means for generating and delivering a ventricular pace pulse to the ventricles of the patient'"'"'s heart at the expiration of the AV delay;
means for setting the AV delay at an initial AV delay at a first time related to the time of implant of the dual chamber pacing system in the patient; and
means for providing a Time-Adaptive AV delay during a post-implant Time-Adaptive period that gradually changes the initial AV delay to a chronic AV delay at the end of the post-implant Time-Adaptive period, wherein the initial AV delay is a longer time interval than the time interval of the chronic AV delay.
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Accused Products
Abstract
Rate responsive pacing systems that employ a time-dependent AV delay in the pacing hearts in Congestive Heart Failure (CHF) with Dilated Cardiomyopathy (DCM) (a CHF/DCM heart) during a post-implant Time-Adaptive period are disclosed. A starting or initial AV delay is set to an intrinsic AV delay time interval exhibited by the patient'"'"'s heart at the time of implant. A chronic AV delay is then set to a therapeutic AV delay time interval that is shorter than the intrinsic AV delay time interval and alleviates symptoms of the CHF/DCM heart. A Time-Adaptive AV delay (TA-AV delay) is employed during a post-implant Time-Adaptive period that gradually changes the initial AV delay to the chronic AV delay at the end of the post-implant Time-Adaptive period.
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Citations
32 Claims
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1. A dual chamber pacing system adapted for pacing a heart in a patient during a post-implant Time-Adaptive period, comprising:
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atrial sense means for sensing an atrial signal from an atria of the patient'"'"'s heart and providing an A-EVENT signal;
AV delay timing means for timing an AV delay from an A-EVENT signal;
ventricular sense means for sensing a ventricular signal from ventricles of the patient'"'"'s heart and providing a V-EVENT signal;
ventricular pace means for generating and delivering a ventricular pace pulse to the ventricles of the patient'"'"'s heart at the expiration of the AV delay;
means for setting the AV delay at an initial AV delay at a first time related to the time of implant of the dual chamber pacing system in the patient; and
means for providing a Time-Adaptive AV delay during a post-implant Time-Adaptive period that gradually changes the initial AV delay to a chronic AV delay at the end of the post-implant Time-Adaptive period, wherein the initial AV delay is a longer time interval than the time interval of the chronic AV delay. - View Dependent Claims (2, 3, 4)
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5. A dual chamber pacing system adapted for pacing a heart in a patient during a post-implant Time-Adaptive period, comprising:
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atrial sense means for sensing an atrial signal from an atria of the patient'"'"'s heart and providing an A-EVENT signal;
AV delay timing means for timing an AV delay from an A-EVENT signal;
ventricular sense means for sensing a ventricular signal from ventricles of the patient'"'"'s heart and providing a V-EVENT signal;
ventricular pace means for generating and delivering a ventricular pace pulse to the ventricles of the patient'"'"'s heart at the expiration of the AV delay;
means for setting the AV delay at an initial AV delay at a first time related to the time of implant of the dual chamber pacing system in the patient; and
means for providing a Time-Adaptive AV delay during a post-implant Time-Adaptive period that gradually changes the initial AV delay to a chronic AV delay at the end of the post-implant Time-Adaptive period, wherein the system is adapted to pace a patient'"'"'s heart exhibiting CHF/DCM, the initial AV delay being set to an intrinsic AV delay time interval exhibited by the patient'"'"'s heart, the chronic AV delay being set to a therapeutic AV delay time interval that is shorter than the intrinsic AV delay time interval and alleviates symptoms of the CHF/DCM heart. - View Dependent Claims (6, 7, 8)
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9. A method of operating a dual chamber pacing system adapted for pacing a heart in a patient during a post-implant Time-Adaptive period, the method comprising:
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sensing an atrial signal from an atria of the patient'"'"'s heart and providing an A-EVENT signal;
timing an AV delay from A-EVENT signal;
sensing a ventricular signal from ventricles of the patient'"'"'s heart and providing a V-EVENT signal;
generating and delivering a ventricular pace pulse to the ventricles of the patient'"'"'s heart at the expiration of the AV delay;
setting the AV delay at an initial AV delay at a first time related to the time of implant of the dual chamber pacing system in the patient; and
providing a Time-Adaptive AV delay during a post-implant Time-Adaptive period that gradually changes the initial AV delay to a chronic AV delay at the end of the post-implant Time-Adaptive period, the initial AV delay having a longer time interval than the time interval of the chronic AV delay. - View Dependent Claims (10, 11, 12)
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13. A method of operating a dual chamber pacing system adapted for pacing a heart in a patient during a post-implant Time-Adaptive period, the method comprising:
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sensing an atrial signal from the atria of the patient'"'"'s heart and providing an A-EVENT signal;
timing an AV delay from an A-EVENT signal;
sensing a ventricular signal from the ventricles of the patient'"'"'s heart and providing a V-EVENT signal;
generating and delivering a ventricular pace pulse to the ventricles of the patient'"'"'s heart at the expiration of the AV delay;
setting the AV delay at an initial AV delay at a first time related to the time of implant of the dual chamber pacing system in the patient; and
providing a Time-Adaptive AV delay during a post-implant Time-Adaptive period that gradually changes the initial AV delay to a chronic AV delay at the end of the post-implant Time-Adaptive period, wherein the system is particularly adapted to pace a patient'"'"'s heart exhibiting CHF/DCM, the initial AV delay being set to an intrinsic AV delay time interval exhibited by the patient'"'"'s heart, the chronic AV delay being set to a therapeutic AV delay time interval that is shorter than the intrinsic AV delay time interval and alleviates symptoms of the CHF/DCM heart. - View Dependent Claims (14, 15, 16)
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17. A dual chamber pacing system adapted for pacing a patient'"'"'s heart during a post-implant Time-Adaptive period, comprising:
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atrial escape interval timing means for timing an atrial pacing escape interval;
atrial pace means for generating and delivering an atrial pace pulse to an atria of the patient'"'"'s heart at the expiration of the atrial pacing escape interval;
atrial sense means for sensing an atrial signal from the atria of the patient'"'"'s heart and providing an A-EVENT signal;
AV delay timing means for timing a sense AV (SAV) delay from an A-EVENT signal and a pace AV (PAV) delay from expiration of the atrial pacing escape interval;
ventricular sense means for sensing ventricular signals from ventricles of the patient'"'"'s heart and providing a V-EVENT signal;
ventricular pace means for generating and delivering ventricular pace pulses to the ventricles of the patient'"'"'s heart at the expiration of the SAV or PAV delay;
means for setting one or both of the SAV and PAV delay at a time related to the time of implant of the dual chamber pacing system in the patient to one of an initial SAV and PAV delay; and
means for providing one or both of a Time-Adaptive SAV delay and PAV delay during a post-implant Time-Adaptive period that gradually changes the initial one of the SAV and PAV delay to a chronic SAV and PAV delay at the end of the post-implant Time-Adaptive period, wherein the initial SAV delay and PAV delay are longer time intervals than the time intervals of the chronic SAV delay and PAV delay. - View Dependent Claims (18, 19, 20)
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21. A dual chamber pacing system adapted for pacing a patient'"'"'s heart during a post-implant Time-Adaptive period, comprising:
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atrial escape interval timing means for timing an atrial pacing escape interval;
atrial pace means for generating and delivering an atrial pace pulse to an atria of the patient'"'"'s heart at the expiration of the atrial pacing escape interval;
atrial sense means for sensing an atrial signal from the atria of the patient'"'"'s heart and providing an A-EVENT signal;
AV delay timing means for timing a sense AV (SAV) delay from an A-EVENT signal and a pace AV (PAV) delay from expiration of the atrial pacing escape interval;
ventricular sense means for sensing ventricular signals from ventricles of the patient'"'"'s heart and providing a V-EVENT signal;
ventricular pace means for generating and delivering ventricular pace pulses to the ventricles of the patient'"'"'s heart at the expiration of the SAV or PAV delay;
means for setting one or both of the SAV and PAV delay at a time related to the time of implant of the dual chamber pacing system in the patient to one of an initial SAV and PAV delay; and
means for providing one or both of a Time-Adaptive SAV delay and PAV delay during a post-implant Time-Adaptive period that gradually changes the initial one of the SAV and PAV delay to a chronic SAV and PAV delay at the end of the post-implant Time-Adaptive period, the system being adapted to pace a patient'"'"'s heart exhibiting CHF/DCM, the initial SAV delay and PAV delay being set to an intrinsic SAV delay and PAV delay time interval exhibited by the patient'"'"'s heart, the chronic SAV delay and PAV delay being set to a therapeutic SAV delay and PAV delay time interval that is shorter than the intrinsic SAV delay and PAV delay time interval and alleviates symptoms of the CHF/DCM heart. - View Dependent Claims (22, 23, 24)
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25. A method of operating a dual chamber pacing system adapted for pacing a patient'"'"'s heart during a post-implant Time-Adaptive period, the method comprising:
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timing an atrial pacing escape interval;
generating and delivering an atrial pace pulse to the atria of the patient'"'"'s heart at the expiration of the atrial escape interval;
timing a pace AV (PAV) delay from expiration of the atrial escape interval;
sensing an atrial signal from the atria of the patient'"'"'s heart and providing an A-EVENT signal;
timing a sense AV (SAV) delay from an A-EVENT signal;
sensing ventricular signals from the ventricles of the patient'"'"'s heart and providing a V-EVENT signal;
generating and delivering ventricular pace pulses to the ventricles of the patient'"'"'s heart at the expiration of the SAV or PAV delay;
setting one or both of the SAV and PAV delay at a time related to the time of implant of the dual chamber pacing system in the patient to one of an initial SAV and PAV delay; and
providing one or both of a Time-Adaptive SAV delay and PAV delay during a post-implant Time-Adaptive period that gradually changes the initial one of the SAV and PAV delay to a chronic SAV and PAV delay at the end of the post-implant Time-Adaptive period, the initial SAV delay and PAV delays having longer time intervals than the time intervals of the chronic SAV delay and PAV delay. - View Dependent Claims (26, 27, 28)
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29. A method of operating a dual chamber pacing system adapted for pacing a patient'"'"'s heart during a post-implant Time-Adaptive period, the method comprising:
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timing an atrial pacing escape interval;
generating and delivering an atrial pace pulse to the atria of the patient'"'"'s heart at the expiration of the atrial escape interval;
timing a pace AV (PAV) delay from expiration of the atrial escape interval;
sensing an atrial signal from the atria of the patient'"'"'s heart and providing an A-EVENT signal;
timing a sense AV (SAV) delay from an A-EVENT signal;
sensing ventricular signals from the ventricles of the patient'"'"'s heart and providing a V-EVENT signal;
generating and delivering ventricular pace pulses to the ventricles of the patients heart at the expiration of the SAV or PAV delay;
setting one or both of the SAV and PAV delay at a time related to the time of implant of the dual chamber pacing system in the patient to one of an initial SAV and PAV delay; and
providing one or both of a Time-Adaptive SAV delay and PAV delay during a post-implant Time-Adaptive period that gradually changes the initial one of the SAV and PAV delay to a chronic SAV and PAV delay at the end of the post-implant Time-Adaptive period, the system being particularly adapted to pace a patient'"'"'s heart exhibiting CHF/DCM, the initial SAV delay and PAV delay being set to an intrinsic SAV delay and PAV delay time interval exhibited by the patient'"'"'s heart, the chronic SAV delay and PAV delay being set to a therapeutic SAV delay and PAV delay time interval that is shorter than the intrinsic SAV delay and PAV delay time interval and alleviates symptoms of the CHF/DCM heart. - View Dependent Claims (30, 31)
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32. A method of operating a dual chamber pacing system adapted for pacing a patient'"'"'s heart during a post-implant Time-Adaptive period, the method comprising:
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timing an atrial pacing escape interval;
generating and delivering an atrial pace pulse to the atria of the patient'"'"'s heart at the expiration of the atrial escape interval;
timing a pace AV (PAV) delay from expiration of the atrial escape interval;
sensing an atrial signal from the atria of the patient'"'"'s heart and providing an A-EVENT signal;
timing a sense AV (SAV) delay from an A-EVENT signal;
sensing ventricular signals from the ventricles of the patient'"'"'s heart and providing a V-EVENT signal;
generating and delivering ventricular pace pulses to the ventricles of the patient'"'"'s heart at the expiration of the SAV or PAV delay;
setting one or both of the SAV and PAV delay at a time related to the time of implant of the dual chamber pacing system in the patient to one of an initial SAV and PAV delay; and
providing one or both of a Time-Adaptive SAV delay and PAV delay during a post-implant Time-Adaptive period that gradually changes the initial one of the SAV and PAV delay to a chronic SAV and PAV delay at the end of the post-implant Time-Adaptive period, the Time-Adaptive SAV delay and PAV delay being non-linearly decremented In time interval from the initial SAV delay and PAV delay to the chronic SAV delay and PAV delay in decrement steps over the post-implant Time-Adaptive period.
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Specification