Syringe plunger having an improved sealing ability

• US 6,511,459 B1
• Filed: 09/29/2000
• Issued: 01/28/2003
• Est. Priority Date: 09/29/2000
• Status: Expired due to Term

• Current Assignee: Liebel-Flarsheim Company (Mallinckrodt plc)
• Original Assignee: Mallinckrodt Incorporated (Mallinckrodt plc)
• Inventors: Fago, Frank M.
• Primary Examiner(s): Walberg, Teresa
• Assistant Examiner(s): FASTOVSKY, LEONID M
• Application Number:
  US09/676,143
• Time in Patent Office: 851 Days
• Field of Search: 604/181, 604/110, 604/187, 604/218, 604/183, 604/227, 604/72, 604/573, 604/82, 600/579
• US Class Current: 604/181
• CPC Class Codes: A61M 2005/31516 reducing dead-space in the syringe barrel after delivery
• CPC Class Codes: A61M 5/31511 Piston or piston-rod constructions, e.g. connection of piston with piston-rod A61M5/5066 takes precedence
• CPC Class Codes: A61M 5/31513 Piston constructions to improve sealing or sliding

Abstract

A plunger is provided for a syringe that includes a pressure relief mechanism that exhausts any fluid trapped in the chamber between sealing flanges carried by the plunger when the plunger is advanced to dispense fluid from the syringe. The contact pressure between the barrel-contacting surface of the rearmost sealing flange nearest the access opening of the syringe barrel is weakened relative to the contact pressure provided by the barrel-contacting surface of the sealing flange that isolates the fluid within the barrel. The contact pressure of the rearmost sealing flange may be lessened by either reducing its radial diameter relative to the radial diameter of the other sealing flange, removing an underlying portion of the plunger, or configuring the rearmost sealing flange as deflectable sealing lip.

Claims

1. A plunger for use with a syringe having a barrel filled with a liquid that exerts a fluid pressure on the plunger when the plunger is in motion, the barrel having a cylindrical wall with an interior surface and a longitudinal axis extending between a proximal end and a distal end, a discharge outlet at the distal end through which the liquid passes when dispensed, and an access opening at the proximal end for applying a dispensing force to move the plunger in a proximal-to-distal direction toward the discharge outlet, said plunger comprising:

a piston operably mounted within the syringe barrel for dispensing the liquid from the discharge outlet, said piston including a chamber susceptive of trapping a portion of the liquid when the piston is in motion, said piston having a circumferential first sealing flange exerting a fluid-tight contact pressure with the interior surface of the syringe barrel distally of the chamber and a circumferential second sealing flange exerting a lesser contact pressure with the interior surface of the syringe barrel proximally of the chamber to allow the portion of the liquid trapped in the chamber to be exhausted between the second sealing flange and the interior surface in a proximal direction when the dispensing force is applied to said piston in a proximal-to-distal direction for dispensing liquid from the barrel through the distal discharge outlet, so that the fluid-tight seal between said first sealing flange and the interior surface is undisturbed.

2. The plunger of claim 1, wherein said chamber has the shape of an annulus and is disposed between said first and second sealing flanges.

3. The plunger of claim 1, wherein said first sealing flange has a radially outermost barrel-contacting sealing surface located at a first predetermined radial distance from the longitudinal axis of the barrel and said second sealing flange has a radially outermost barrel-contacting sealing surface of a lesser second predetermined radial distance from the longitudinal axis of the barrel.

4. The plunger of claim 3, wherein said second predetermined radial distance is about 10 mils less than said first predetermined radial distance.

5. The plunger of claim 3, wherein said first and second sealing flanges have generally circular cross-sectional profiles when in an uncompressed state.

6. The plunger of claim 5, wherein said second predetermined radial distance is about 10 mils less than said first predetermined radial distance.

7. The plunger of claim 3, wherein said second sealing flange comprises a circumferential sealing lip projecting in a radially outward and proximal direction from a cylindrical outer surface of said piston, said lip having a barrel-contacting sealing surface that contacts the interior surface of the syringe barrel such that said lip deflects proximally to exhaust liquid trapped in said chamber.

8. The plunger of claim 7, wherein said first sealing flange has a generally circular cross-sectional profile of a first predetermined radius, when in an uncompressed state.

9. The plunger of claim 1, wherein said piston further includes a cylindrical outer surface and a conical head that is positioned proximal of said outer surface and is integral with said outer surface, wherein a substantial portion of said conical head is in contact with the liquid in the barrel.

10. The plunger of claim 9, wherein said conical head tapers to an included angle of about 120°

.

11. The plunger of claim 1, wherein the piston further comprises an inner member and a sheath surrounding an exterior surface of said inner member, said sheath including a cylindrical sidewall and said first and second sealing flanges project radially outwardly from an exterior surface of said sidewall, wherein said second sealing flange is spaced proximally of said first sealing flange so as to define therebetween said chamber.

12. The plunger of claim 11, wherein the exterior surface of said inner member is at least partially removed radially inwardly of said second sealing flange.

13. The plunger of claim 11, wherein the sidewall of said sheath has an interior surface that is at least partially removed radially inwardly of said second sealing flange.

14. The plunger of claim 11, wherein said sidewall and said first and second sealing flanges have an integral, one-piece configuration.

15. The plunger of claim 11, wherein said sheath further includes a conical head that is integral with said sidewall, wherein a substantial portion of said conical head contacts the liquid within the barrel.

16. The plunger of claim 15, wherein said conical head tapers to an included angle of about 120°

.

17. The plunger of claim 11, wherein said chamber has the shape of an annulus.

18. The plunger of claim 11, wherein said second sealing flange is substantially circumferentially continuous and exerts a second contact pressure on the interior surface of the barrel lesser than the first contact pressure exerted by said first sealing flange, so that any liquid trapped in said annular chamber is exhausted in a proximal direction without disturbing the fluid-tight seal of said first sealing flange.

19. The plunger of claim 11, wherein said first sealing flange has a radially outermost barrel-contacting sealing surface located at a first predetermined radial distance from the longitudinal axis of the barrel and said second sealing flange has a radially outermost barrel-contacting sealing surface of a lesser second predetermined radial distance from the longitudinal axis of the barrel.

20. The plunger of claim 19, wherein sad second predetermined radial distance is about 10 mils less than said first predetermined radial distance.

21. The plunger of claim 19, wherein said first and second sealing flanges have generally circular cross-sectional profiles when in an uncompressed state.

22. The plunger of claim 21, wherein said second predetermined radial distance is about 10 mils less than said first predetermined radial distance.

23. The plunger of claim 11, wherein said second sealing flange comprises a circumferential sealing lip projecting in a radially outward and proximal direction from said exterior surface of said cylindrical sidewall, said sealing lip having a barrel-containing sealing portion that contacts the interior surface of the barrel such that said lip deflects proximally to exhaust liquid trapped in said chamber.

24. The plunger of claim 23, wherein said first sealing flange has a generally circular cross-sectional profile of a first predetermined radius when in an uncompressed state.

25. A sheath for attachment to the exterior of an inner member to provide a syringe plunger, the sheath for providing a sealing engagement an the interior surface of a syringe barrel that has a longitudinal axis with a distal end and a proximal end, a distal discharge opening for dispensing a liquid held by the barrel, and a longitudinal axis, the sheath comprising:

a cylindrical sidewall having an exterior surface, a proximal end and a distal end;

a head that is integral with the distal end of the sidewall, wherein said sidewall and said head are configured for receiving the exterior of the inner member in a snug fit;

a first circumferential sealing flange projecting radially outwardly from said exterior surface of said sidewall, said first sealing flange being substantially circumferentially continuous and exerting a sufficient first contact pressure on the interior surface of the syringe barrel to maintain a fluid-tight seal therewith; and

a second circumferential sealing flange projecting radially outwardly from the exterior surface of the sidewall, said second sealing flange in a spaced position proximally of the first sealing flange so as to define therebetween a chamber susceptive of trapping a portion of the liquid when the piston is in motion, wherein said second sealing flange exerts a second contact pressure lesser than the first contact pressure of the first sealing flange that permits any liquid trapped in the chamber to be exhausted between the second sealing flange and the interior surface in a proximal direction when a dispensing force is applied to the syringe plunger to move the plunger for dispensing liquid from the barrel through the distal discharge outlet, so that the fluid-tight seal between said first sealing flange and the interior surface is undisturbed.

26. The sheath of claim 25, wherein said chamber has the shape of an annulus.

27. The sheath of claim 25, wherein said first sealing flange has a radially outermost barrel-contacting sealing surface located at a first predetermined radial distance from the longitudinal axis of the barrel and said second sealing flange has a radially outermost barrel-contacting sealing surface of a lesser second predetermined radial distance from the longitudinal axis of the barrel.

28. The sheath of claim 27, wherein said second predetermined radial distance is about 10 mils less than said first predetermined radial distance.

29. The sheath of claim 28, wherein said first and second sealing flanges have generally circular cross-sectional profiles when in an uncompressed state.

30. The sheath of claim 29, wherein said second predetermined radial distance is about 10 mils less than said first predetermined radial distance.

31. The sheath of claim 25, wherein said second sealing flange comprises a circumferential sealing lip projecting in a radially outward and proximal direction from said exterior surface of said cylindrical sidewall, said sealing lip having a barrel-containing sealing surface that contacts the interior surface of the syringe barrel such that said lip deflects proximally to exhaust liquid trapped in said chamber.

32. The sheath of claim 31, wherein said first sealing flange has a generally circular cross-sectional profile of a first predetermined radius when in an uncompressed state.

33. The sheath of claim 25, wherein said head is a conical head.

34. The sheath of claim 33, wherein said conical head tapers to an included angle of about 120°

.

35. A syringe for dispensing a liquid when acted upon by a dispensing force, said syringe comprising:

a tubular barrel having a cylindrical wall with a proximal end, a distal end, a longitudinal axis, an interior surface, a proximal access opening, and a distal discharge outlet, wherein the barrel is adapted for holding a liquid; and

a plunger operably mounted within the barrel for dispensing the liquid from the discharge opening, said plunger including a chamber susceptive of trapping a portion of the liquid when the plunger is in motion, said plunger having a circumferential first sealing flange exerting a fluid-tight contact pressure with the interior surface of the tubular barrel distally of the chamber and a circumferential second sealing flange exerting a lesser contact pressure with the interior surface of the syringe barrel proximally of the chamber to allow the portion of the liquid trapped in the chamber to be exhausted between the second sealing flange and the interior surface in a proximal direction when the dispensing force is applied to said piston in a proximal-to-distal direction for dispensing liquid from the barrel through the distal discharge outlet, so that the fluid-tight seal between said first sealing flange and the interior surface is undisturbed.

36. The syringe of claim 35, wherein said chamber has the shape of an annulus and is disposed between said first and said second sealing flanges.

37. The syringe of claim 35, wherein said first sealing flange has a radially outermost barrel-contacting sealing surface located at a first predetermined radial distance from the longitudinal axis of the barrel and said second sealing flange has a radially outermost barrel-contacting sealing surface of a lesser second predetermined radial distance from the longitudinal axis of the barrel.

38. The syringe of claim 37, wherein said second predetermined radial distance is about 10 mils less than said first predetermined radial distance.

39. The syringe of claim 37, wherein said first and second sealing flanges have generally circular cross-sectional profiles when in an uncompressed state.

40. The syringe of claim 39, wherein said second predetermined radial distance is about 10 mils less than said first predetermined radial distance.

41. The syringe of claim 35, wherein said second sealing flange comprises a circumferential sealing lip projecting in a radially outward and proximal direction from an outer surface of said plunger, said lip having a barrel-contacting sealing surface that contacts the interior surface of the syringe barrel such that said lip deflects proximally to exhaust liquid trapped in said chamber.

42. The syringe of claim 41, wherein said first sealing flange has a generally circular cross-sectional profile of a first predetermined radius when in an uncompressed state.

43. The syringe of claim 35, wherein said plunger further includes a conical head that is integral with said sidewall.

44. The syringe of claim 43, wherein said conical head tapers to an included angle of about 120°

.

45. The syringe of claim 35, wherein the plunger further comprises an inner member and a sheath surrounding the exterior surface of said inner member, said sheath including a cylindrical sidewall and said first and second sealing flanges project radially outwardly from an exterior surface of said sidewall, wherein said second sealing flange is spaced proximally of the first sealing flange so as to define the chamber therebetween.

46. The syringe of claim 45, wherein the exterior surface of said inner member is at least partially removed radially inwardly of said second sealing flange.

47. The syringe of claim 45, wherein the sidewall of said sheath has an interior surface that is at least partially removed radially inwardly of said second sealing flange.

48. The syringe of claim 45, wherein said sidewall and said circumferential sealing flanges have an integral, one-piece configuration.

49. The syringe of claim 45, wherein said sheath further includes a head that is integral with said sidewall, said head in contact with said liquid, wherein a substantial portion of said conical head contacts the liquid within the barrel.

50. The syringe of claim 49, wherein said head is conical and tapers to an included angle of about 120°

.

51. The syringe of claim 45, wherein said chamber has the shape of an annulus.

52. The syringe of claim 45, wherein said second sealing flange being substantially circumferentially continuous and exerting a second contact pressure on said inside surface of the barrel lesser than the first contact pressure exerted by said first sealing flange, so that any liquid trapped in the annular chamber is exhausted in a proximal direction without disturbing the fluid-tight seal of said first sealing flange.

53. The syringe of claim 45, wherein said first sealing flange has a radially outermost barrel-contacting sealing surface located at a first predetermined radial distance from the longitudinal axis of the barrel and said second sealing flange has a radially outermost barrel-contacting sealing surface of a lesser second predetermined radial distance from the longitudinal axis of the barrel.

54. The syringe of claim 53, wherein said second predetermined radial distance is about 10 mils less than said first predetermined radial distance.

55. The syringe of claim 53, wherein said first and second sealing flanges have generally circular cross-sectional profiles when in an uncompressed state.

56. The syringe of claim 55, wherein said second predetermined radial distance is about 10 mils less than said first predetermined radial distance.

57. The syringe of claim 52, wherein said second sealing flange comprises a circumferential sealing lip projecting in a radially outward and proximal direction from said exterior surface of said cylindrical sidewall, said lip having a barrel-contacting sealing surface that contacts the inside surface of the syringe barrel such that said lip deflects proximally to exhaust liquid trapped in said chamber.

58. The syringe of claim 57, wherein said first sealing flange has a generally circular cross-sectional profile of a first predetermined radius when in an uncompressed state.

59. The syringe of claim 35, further comprising a quantity of a liquid within said tubular barrel, said liquid suitable for injection into a patient.

60. The syringe of claim 59, wherein said liquid is an imaging contrast agent and the quantity of imaging contrast agent is sufficient to facilitate an imaging operation.

61. A method for dispensing a liquid imaging medium with a dispensing force, the method comprising:

providing a syringe barrel having a forward end with a discharge outlet, an interior surface and an open rearward end;

providing a plunger within said syringe barrel, said plunger including a chamber susceptive of trapping a portion of a liquid present in the syringe barrel when the plunger is in motion and said plunger located forward of the chamber and having a first circumferential sealing flange configured to normally provide a first contact pressure with said interior surface of the syringe barrel, and a second sealing flange located rearward of the chamber and configured to provide a lesser second contact pressure of a fluid-tight magnitude with said interior surface of the syringe barrel, wherein said second sealing flange preferentially exhausts trapped liquid imaging medium from the chamber in a rearward direction when a dispensing force is applied to said piston for dispensing liquid from the barrel through the discharge outlet;

filling the syringe barrel forward of the plunger with a quantity of a liquid imaging medium;

connecting the syringe to a patient via a catheter and a tube interconnecting catheter and the discharge outlet of the syringe barrel; and

applying a dispensing force to the plunger for dispensing liquid imaging medium from the syringe into the patient, wherein liquid imaging medium trapped in the chamber is preferentially exhausted between the second sealing flange and said interior surface in a rearward direction due to the lesser contact pressure exerted by the second sealing flange against the interior surface of the syringe barrel.

62. The method of claim 61 wherein the step of filling the syringe barrel with a quantity of liquid imaging medium occurs before the step of providing the plunger.

63. The method of claim 61 wherein the step of filling the syringe barrel with a quantity of liquid imaging medium occurs after the step of providing the plunger, and the step of filling comprises placing the outlet opening in fluid communication with a reservoir of liquid imaging medium and siphoning the liquid imaging medium through the outlet opening by moving the plunger in a rearward direction within the syringe barrel.