Method for reducing coronary artery reactivity
First Claim
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1. A method for prophylactically treating myocardial ischemia comprising administering to a subject in need thereof an effective amount of progesterone.
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Abstract
A method for reducing coronary artery reactivity. A predetermined amount of natural progesterone is provided by a convenient and pleasant delivery system to the blood stream, sufficient to reduce the likelihood of coronary vasospasm and myocardial ischemia. The progesterone may be provided either by topical application to the epidermis of a cream in which the progesterone is dissolved or by patch technology, so as to provide continuous delivery and thereby maintain the level of progesterone in the blood stream at least about 1 nanogram per milliliter.
60 Citations
6 Claims
- 1. A method for prophylactically treating myocardial ischemia comprising administering to a subject in need thereof an effective amount of progesterone.
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4. A method for increasing the beneficial effects of estrogen for prophylactically treating acute myocardial ischemia, comprising administering to a subject being administered estrogen an effective amount of progesterone.
- 5. A method for prophylactically treating angina pectoris comprising administering to a patient in need thereof an effective amount of progesterone.
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Current AssigneeDimera Incorporated
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Original AssigneeDimera Incorporated
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InventorsHermsmeyer, R. Kent
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Primary Examiner(s)Travers, Russell
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Assistant Examiner(s)Wells, Lauren Q.
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Application NumberUS09/548,476Time in Patent Office1,020 DaysField of Search424/449, 514/171, 514/177, 514/843, 514/861, 514/863, 514/899, 514/970, 514/170, 514/182US Class Current514/177CPC Class CodesA61K 31/57 substituted in position 17 ...
