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Substituted 2-phenyl-1-(3,4-dihydroxy-5-nitrophenyl)-1-ethanones, their use in the treatment of some central and peripheral nervous system disorders and pharmaceutical compositions containing them

  • US 6,512,136 B1
  • Filed: 12/17/1999
  • Issued: 01/28/2003
  • Est. Priority Date: 12/18/1998
  • Status: Expired due to Fees
First Claim
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1. A compound of formula I:

  • embedded imagewhere R1 and R2 are the same or different and signify hydrogens, optionally substituted lower alkanoyl or aroyl groups, or optionally substituted lower alkylcarbamoyl groups;

    R3, R4 and R5 are the same or different and signify hydrogens, optionally substituted saturated or partially unsaturated lower hydrocarbon residues, hydroxyls, optionally substituted lower alkoxy or aryloxy groups, optionally substituted aryl, optionally substituted alkanoyl or aroyl groups, lower alkanoylamino groups, lower dialkanoylamino groups, optionally substituted lower alkyloxycarbonyl or aryloxycarbonyl groups, optionally substituted carbamoyl, halogen, amino, lower alkylamino or lower dialkylamino groups, or taken together signify aliphatic or heteroaliphatic rings or aromatic or heteroaromatic rings, and pharmaceutically acceptable salts thereof.

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