System and method for automatically verifying capture during multi-chamber stimulation

• US 6,512,953 B2
• Filed: 04/26/2001
• Issued: 01/28/2003
• Est. Priority Date: 05/11/2000
• Status: Active Grant

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Inventors: Florio, Joseph J., Bradley, Kerry, Bornzin, Gene A., Park, Euljoon
• Primary Examiner(s): Getzow, Scott M.
• Application Number:
  US09/844,189
• Publication Number:
  US 20010049542A1
• Time in Patent Office: 642 Days
• Field of Search: 607/27, 607/28
• US Class Current: 607/28
• CPC Class Codes: A61N 1/3627 for treating a mechanical deficiency of the heart, e.g. congestive heart failure or cardiomyopathy
• CPC Class Codes: A61N 1/3712 Auto-capture, i.e. automatic adjustment of the stimulation threshold

Abstract

A system and corresponding method are provided to reliably detect capture during multi-chamber stimulation, and to further monitor the progression of congestive heart failure. The system provides a method by which intracardiac electrogram (IEGM) characteristics representing single-chamber capture and bi-ventricular capture are stored in memory and displayed. The annotation of the displayed waveforms is such that events associated with loss of capture, single-chamber capture, and bi-ventricular capture are clearly marked for ready interpretation by the physician. In a first situation, a stimulation pulse is followed by a time delay window and a subsequent depolarization complex that represents intrinsic responses of the chambers that have not been captured. In a second situation, a stimulation pulse is followed almost immediately by an evoked response that represents capture of one chamber, and a subsequent depolarization complex that represents an intrinsic response of one chamber that has not been captured. In a third situation, a stimulation pulse is almost immediately followed by an evoked response that represents simultaneous capture of two chambers.

Claims

1. A cardiac stimulation device comprising:

a pulse generator that selectively generates stimulation pulses for delivery to a pair of opposite chambers of a patient'"'"'s heart;

a detector that detects intracardiac electrogram (IEGM) signals of the selected pair of chambers subsequent to the delivery of the stimulation pulses; and

a controller, coupled to the detector and the pulse generator, that is operative to compare the detected IEGM signals with stored data to distinguish between no capture occurring in either chamber, capture occurring in only one of the selected chambers, and capture occurring in both of the selected chambers.

2. The cardiac stimulation device according to claim 1, wherein the controller is operative to trigger the pulse generator to increase the stimulation pulse energy if either no capture or capture in only one of the selected chambers occurs.

3. The cardiac stimulation device according to claim 1, wherein the pulse generator is operative to deliver stimulation pulses to a right and left ventricle.

4. The cardiac stimulation device according to claim 1, wherein the pulse generator is operative to deliver stimulation pulses to a right and left atrium.

5. The cardiac stimulation device according to claim 1, wherein the controller is operative to compare at least one characteristic of the detected IEGM signals with the stored data, wherein the at least one characteristic comprises at least one of:

a template representation of an overall intra-cardiac electrogram (IEGM) waveform;

a peak negative amplitude;

a peak positive amplitude;

a positive slope;

a negative slope;

a positive integral;

a negative integral;

a plurality of inflection points;

an average time duration of a plurality of depolarizations;

a time interval between a stimulation pulse and any subsequently detected event;

or

a time interval between consecutively detected events.

6. A method comprising:

storing capture data corresponding to expected waveforms resulting from at least one of non-capture, single chamber capture, and bi-chamber capture;

stimulating two chambers of a heart, where the two chambers comprise one of both atria and both ventricles;

detecting a corresponding intracardiac electrogram (IEGM) signal; and

comparing the IEGM signal with the stored capture data to determine whether the IEGM signal corresponds with the stored capture data.

7. The method according to claim 6, further comprising increasing a stimulation energy applied to the two chambers when the IEGM signal corresponds with either non-capture or capture of only one chamber.

8. The method according to claim 6, wherein comparing the IEGM signal and the stored capture data comprises comparing at least one parameter of the IEGM signal that defines a morphology of the IEGM signal with the stored capture data.

9. The method according to claim 8, wherein comparing comprises comparing at least one of:

a peak amplitude, a slope, an integration of a waveform, and a timing interval estimation.

10. The method according to claim 6, wherein storing capture data comprises storing capture data representative of non-capture of both chambers, single-chamber capture, and bi-chamber capture.

11. The method according to claim 10, wherein comparing comprises comparing the IEGM signal to the stored capture data representative of each result.