Device for removal of thrombus through physiological adhesion

• US 6,514,273 B1
• Filed: 03/22/2000
• Issued: 02/04/2003
• Est. Priority Date: 03/22/2000
• Status: Expired due to Term

• Current Assignee: Abbott Cardiovascular Systems Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: EndoVascular Technologies Incorporated (Boston Scientific Corporation)
• Inventors: Tremulis, William Stephen, Voss, Larry
• Primary Examiner(s): Milano, Michael J.
• Assistant Examiner(s): HO, TAN-UYEN THI
• Application Number:
  US09/532,629
• Time in Patent Office: 1,049 Days
• Field of Search: 606/200, 606/108, 606/113, 606/114, 606/159, 606/194, 604/527, 604/265, 604/266
• US Class Current: 606/200
• CPC Class Codes: A61B 17/22 Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for dilators A61M29/00
• CPC Class Codes: A61B 17/22031 Gripping instruments, e.g. forceps, for removing or smashing calculi A61B17/221 takes precedence
• CPC Class Codes: A61B 17/221 Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions surgical snare instruments A61B17/32056
• CPC Class Codes: A61B 2017/00287 Bags for minimally invasive surgery
• CPC Class Codes: A61B 2017/22002 preventing restenosis
• CPC Class Codes: A61B 2017/22034 for gripping the obstruction or the tissue part from inside
• CPC Class Codes: A61B 2017/2212 having a closed distal end, e.g. a loop
• CPC Class Codes: A61F 2002/016 made from wire-like elements
• CPC Class Codes: A61F 2002/018 made from tubes or sheets of material, e.g. by etching or laser-cutting
• CPC Class Codes: A61F 2230/0006 circular
• CPC Class Codes: A61F 2230/0067 conical
• CPC Class Codes: A61F 2230/0069 cylindrical
• CPC Class Codes: A61F 2230/0091 helically-coiled or spirally-coiled, i.e. having a 2-D spiral cross-section
• CPC Class Codes: A61M 2025/0042 Microcatheters, cannula or the like having outside diameters around 1 mm or less
• CPC Class Codes: A61M 2025/109 having balloons for removing solid matters, e.g. by grasping or scraping plaque, thrombus or other matters that obstruct the flow
• CPC Class Codes: A61M 2202/045 Fibrin

Abstract

A device that is useful for removing obstructions from vessels. Various embodiments and methods of use are contemplated for the effective removal of obstructions. The disclosed devices utilize a thrombogenic material to promote the formation of fibrin bonds, thus enhancing adhesion. It is further contemplated that the disclosed devices may be used in all vasculature including the cerebral vasculature and the neurovasculature.

Claims

1. A system for removing an obstruction from a vessel, comprising:

an elongate tubular member having a proximal end and a distal end; and

an elongate element having a proximal end, a distal end, and a midsection at least a portion of which is positionable within the elongate tubular member, wherein the distal end of the elongate element includes a capture device operatively connected to the elongate element, wherein the capture device is coated with a thrombogenic material and can assume an expanded condition and a contracted condition.

2. The system of claim 1, wherein the elongate tubular member is a microcatheter.

3. The system of claim 1, wherein the adhesion is at least in part accomplished by fibrin bonds.

4. The system of claim 1, wherein the distal end of the elongate element is coated with a thrombogenic material.

5. The system of claim 1, wherein the distal end of the elongate element includes a capture device operatively connected to the elongate element, wherein the capture device can assume an expanded condition and a contracted condition.

6. The system of claim 1, wherein the capture device is self-deploying and includes knitted superelastic wire.

7. The system of claim 5, wherein the capture device is coated with a thrombogenic material.

8. The system of claim 1, wherein the capture device includes a mesh-like structure.

9. The system of claim 5, wherein the capture device has a pore.

10. The system of claim 1, wherein the distal end of the elongate element has a ribbon attached thereto.

11. The system of claim 10, wherein the ribbon has a helical shape.

12. The system of claim 10, wherein the ribbon is self-deploying and can assume an expanded condition and a contracted condition.

13. The system of claim 10, wherein the ribbon is coated with a thrombogenic material.

14. A method for removing an obstruction from a vessel, utilizing a system including a member having a proximal end and a distal end including a capture device coated with a thrombogenic material and being capable of assuming an expanded condition and a contracted condition, comprising the steps of:

advancing the system to a treatment site;

inserting the distal end of the member into the obstruction and allowing the capture device coated with a thrombogenic material to assume an expanded condition, wherein the distal end promotes adhesion to the obstruction utilizing blood-borne constituents, thereby facilitating removal of the obstruction; and

removing the obstruction from a vessel.