Transmural ablation device and method

• US 6,517,536 B2
• Filed: 04/27/2001
• Issued: 02/11/2003
• Est. Priority Date: 04/27/2000
• Status: Expired due to Term

• Current Assignee: Atricure, Inc.
• Original Assignee: Atricure, Inc.
• Inventors: Hooven, Michael D., Chaldekas, James A.
• Primary Examiner(s): ROLLINS, ROSILAND STACIE
• Application Number:
  US09/844,225
• Publication Number:
  US 20020032440A1
• Time in Patent Office: 655 Days
• Field of Search: 606/41, 606/42, 606/45, 606/46, 606/48, 606/49, 606/50, 607/100, 607/101, 607/115, 607/116, 607/119
• US Class Current: 606/41
• CPC Class Codes: A61B 18/1445 at the distal end of a shaft, e.g. forceps or scissors at the end of a rigid rod
• CPC Class Codes: A61B 2017/00026 Conductivity or impedance, e.g. of tissue
• CPC Class Codes: A61B 2017/00243 cardiac
• CPC Class Codes: A61B 2017/2945 Curved jaws
• CPC Class Codes: A61B 2018/00363 Epicardium
• CPC Class Codes: A61B 2018/00642 with feedback, i.e. closed loop control
• CPC Class Codes: A61B 2018/00755 Resistance or impedance
• CPC Class Codes: A61B 2018/00875 Resistance or impedance
• CPC Class Codes: A61B 2018/1432 curved
• CPC Class Codes: A61B 2018/145 wherein the effectors remain parallel during closing and opening
• CPC Class Codes: A61B 5/01 Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue clinical contact thermometers G01K13/20
• CPC Class Codes: A61B 5/053 Measuring electrical impedance or conductance of a portion of the body

Abstract

A method and apparatus for transmural ablation using an instrument containing two electrodes or cryogenic probes. A clamping force is exerted on the two electrodes or probes such that the tissue of the hollow organ is clamped therebetween. Bipolar RF energy is then applied between the two electrodes, or the probes are cryogenically cooled, thus ablating the tissue therebetween. A monitoring device measures a suitable parameter, such as impedance or temperature, and indicates when the tissue between the electrodes has been fully ablated.

Claims

1. A bipolar left atrium clamp for forming transmural lesions in the wall of the left atrium in a human, the clamp comprising:

first and second substantially rigid jaws having facing surfaces, the jaws being moveable between an open position in which the facing surfaces of the jaws are spaced apart a distance sufficient to receive therebetween opposed walls of the left atrium at a location in proximity to selected pulmonary veins and a clamped position in which opposed wall portions of the left atrium are brought together in a compressed state between the facing surfaces of the jaws, the jaws having a length sufficient to capture a substantial portion of opposing walls of the left atrium therebetween and the jaws being sufficiently rigid so that the facing surfaces are substantially parallel in the clamped position;

a first continuous, elongated electrode carried on the facing surface of the first jaw member and a second continuous, elongated electrode carried on the facing surface of the second jaw member, the electrodes being positioned to be in directly opposed relation in contact with opposed portions of the left atrial wall when said jaws are in the clamped position;

the first and second electrodes being adapted to be connected to an RF energy source so that the first and second electrodes are of opposite polarity;

whereby, when the jaws are clamped about the left atrium and the electrodes are activated with RF energy, an elongated, thin, transmural lesion is simultaneously created in both portions of the clamped left atrial wall.

2. The left atrium clamp of claim 1 wherein the parallel facing surfaces of the jaws are spaced apart when in the clamped position.

3. The left atrium clamp of claim 1 wherein the electrodes have a ratio of length to width of at least 50.

4. The left atrium clamp of claim 1 wherein the electrodes have a width of no greater than 0.6 mm.

5. The left atrium clamp of claim 1 wherein the electrodes are from 3 to 8 cm in length.

6. The left atrium clamp of claim 1 wherein the electrodes are from 0.12 to 0.6 mm in width.

7. A bipolar left atrium clamp for forming transmural lesions in opposed portions of the left atrium in a human, the clamp comprising:

first and second substantially rigid jaws having facing surfaces, the jaws being moveable between an open position in which the facing surfaces of the jaws are spaced apart a distance sufficient to receive therebetween opposed walls of the left atrium at a location in proximity to selected pulmonary veins and a clamped position in which opposed wall portions of the left atrial wall are brought together in a compressed state between the facing surfaces of the jaws, the jaws having a length sufficient to capture a substantial portion of opposing walls of the left atrium therebetween and the jaws being sufficiently rigid so that the facing surfaces are substantially parallel in the clamped position;

a first continuous, elongated electrode carried on the facing surface of the first jaw member and a second continuous, elongated electrode carried on the facing surface of the second jaw member, the electrodes being positioned to be in directly opposed relation in contact with opposed portions of the left atrial wall when said jaws are in the clamped position, the electrodes having a width of no greater than 0.6 mm and a ratio of length to width of at least 50;

the first and second electrodes being adapted to be connected to an RF energy source so that the first and second electrodes are of opposite polarity;

whereby, when the jaws are clamped about the left atrium and the electrodes are activated with RF energy, an elongated, thin, transmural lesion is simultaneously created in both opposed portions of the clamped atrial wall.

8. The left atrium clamp of claim 7 wherein the electrodes are from 3 to 8 cm in length.

9. The left atrium clamp of claim 7 wherein the electrodes are from 0.12 to 0.6 mm in width.

10. The left atrium clamp of claim 7 wherein the parallel facing surfaces of the jaws are spaced apart when in the clamped position.

11. A bipolar left atrium clamp for forming transmural lesions in the wall of the left atrium in a human, the clamp comprising:

first and second substantially rigid jaws having facing surfaces, the jaws being moveable between an open position in which the facing surfaces of the jaws are spaced apart a distance sufficient to receive therebetween opposed walls of the left atrium at a location in proximity to selected pair pulmonary veins and a clamped position in which opposed wall portions of the left atrium are brought together in a compressed state between the facing surfaces of the jaws, the jaws having a length sufficient to extend fully from one side of the left atrium to the other side in proximity to the selected pair of pulmonary veins to isolate the selected pair from the remainder of the left atrium, and the jaws being sufficiently rigid so that the facing surfaces are substantially parallel in the clamped position;

a first continuous, elongated electrode carried on the facing surface of the first jaw member and a second continuous, elongated electrode carried on the facing surface of the second jaw member, the electrodes being positioned to be in directly opposed relation in contact with opposed portions of the left atrial wall when said jaws are in the clamped position, each electrode having a length sufficient to extend fully from one side of the left atrium to the other side;

the first and second electrodes being adapted to be connected to an RF energy source so that the first and second electrodes are of opposite polarity;

whereby, when the jaws are clamped fully about the left atrium in the vicinity of the selected pair of pulmonary veins and the electrodes are activated with RF energy, an elongated, thin, transmural lesion is simultaneously created in both portions of the clamped left atrial wall extending continuously to isolate the selected pair of pulmonary veins from the remainder of the left atrium.