Methods and apparatus for overdrive pacing heart tissue using an implantable cardiac stimulation device

• US 6,519,493 B1
• Filed: 12/23/1999
• Issued: 02/11/2003
• Est. Priority Date: 12/23/1999
• Status: Expired due to Term

• Current Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Original Assignee: Pacesetter Incorporated (Abbott Laboratories Incorporated)
• Inventors: Florio, Joseph J., Poore, John W., Bornzin, Gene A., Kurschinski, Douglas T.
• Primary Examiner(s): Jastrzab, Jeffrey R.
• Assistant Examiner(s): Oropeza, Frances P.
• Application Number:
  US09/471,788
• Time in Patent Office: 1,146 Days
• Field of Search: 600/513, 600/518, 607/4, 607/5, 607/9, 607/14
• US Class Current: 607/9
• CPC Class Codes: A61N 1/368 comprising more than one electrode co-operating with different heart regions A61N1/3622, A61N1/3627 take precedence

Abstract

Techniques are described for overdrive pacing the heart using a pacemaker wherein the overdrive pacing rate only increases when at least two intrinsic beats are detected within a determined search period. In one specific technique, an increase in the pacing rate occurs only if two P-waves are detected within X cardiac cycles. In another specific technique, the overdrive pacing rate is increased only if at least two P-waves are detected within a block of N cardiac cycles. In both techniques, the overdrive pacing rate is decreased if no increase has occurred in the last Z cardiac cycles. By increasing the overdrive pacing rate only in response to detection of at least two P-waves within a determined number of cardiac cycles, an excessively high overdrive pacing rate is avoided. Other techniques are described for adaptively adjusting overdrive pacing parameters so as to achieve a determined target degree of pacing of, for example, 95% paced beats. By adaptively adjusting overdrive parameters to maintain a target degree of pacing, the average overdrive pacing rate is minimized while still maintaining a high number of paced beats, thereby reducing the risk of a tachyarrhythmia occurring within the patient.

Claims

1. A method for controlling overdrive pacing of a patient'"'"'s heart using an implantable cardiac stimulation device connected to the heart, the method comprising the steps of:

determining an overdrive pacing rate;

overdrive pacing the heart at the overdrive pacing rate;

detecting intrinsic heart beats arising during the overdrive pacing; and

if at least two intrinsic heart beats are detected within a first determined search period, increasing the overdrive pacing rate by a determined rate increment; and

if at least two intrinsic heart beats are not detected within a second determined search period, decreasing the overdrive pacing rate by a determined rate decrement.

2. The method of claim 1 wherein the first determined search period extends for a first determined number of overdrive paced cycles.

3. The method of claim 2 wherein the first determined search period begins with a first detected intrinsic beat.

4. The method of claim 3 wherein the first determined search period is between 8 and 40 cycles, inclusive.

5. The method of claim 2 wherein the first determined search period begins with a first paced beat.

6. The method of claim 5 wherein the first determined search period is 10 cycles.

7. The method of claim 1 wherein the second determined search period begins following an increase in the overdrive pacing rate.

8. The method of claim 7 wherein the second determined search period is between 8 and 40 cycles, inclusive.

9. The method of claim 1 wherein the determined rate increment is selected from a group including 5, 10, 15, 20, and 25 ppm.

10. The method of claim 1 wherein the determined rate decrement is selected from a group including 1, 2, 3, 4, and 5 ppm.

11. The method of claim 1 wherein the step of determining the overdrive pacing rate includes the steps of:

determining a sinus rate; and

setting the overdrive pacing rate to be equal to the sinus rate.

12. The method of claim 11 wherein the step of determining the sinus rate includes the steps of:

detecting at least three consecutive sinus P-waves;

determining an average interval between the P-waves; and

calculating the sinus rate based upon the average interval.

13. The method of claim 11 further including the step of periodically re-determining the overdrive pacing rate by:

suspending overdrive pacing;

detecting at least three consecutive P-waves while overdrive pacing is suspended;

determining an updated sinus rate based upon the at least three consecutive P-waves; and

setting the overdrive pacing rate based upon the updated sinus rate.

14. The method of claim 1 wherein the step of determining the overdrive pacing rate includes the steps of:

determining an atrial rate; and

setting the overdrive pacing rate to be equal to the atrial rate.

15. The method of claim 14 further including the steps of:

periodically determining an updated atrial rate;

comparing the updated atrial rate with a current overdrive pacing rate; and

if the updated atrial rate exceeds the current overdrive pacing rate by a determined amount, resetting the overdrive pacing rate to be equal to the updated atrial rate.

16. A system for controlling overdrive pacing of a heart using an implantable cardiac stimulation device configured for connection to a patient'"'"'s heart, the system comprising:

means for determining an overdrive pacing rate;

means for overdrive pacing the heart at the overdrive pacing rate;

means for detecting intrinsic heart beats arising during the overdrive pacing;

means, responsive to detection of at least two intrinsic heart beats within a first determined search period, for increasing the overdrive pacing rate by a determined rate increment; and

means, responsive to detection of no more than one intrinsic heart beat within a second determined search period, for decreasing the overdrive pacing rate by a determined rate decrement.

17. A system for controlling overdrive pacing of a patient'"'"'s heart using an implantable cardiac stimulation device configured for connection to the heart, the system comprising:

a determination unit determining an overdrive pacing rate;

an overdrive pacing unit for overdrive pacing the patient'"'"'s heart at the overdrive pacing rate;

a detection unit for detecting intrinsic heart beats arising during the overdrive pacing;

an overdrive pacing rate increment unit for increasing the overdrive pacing rate by a determined rate increment in response to detection of at least two intrinsic heart beats within a first determined search period; and

wherein the overdrive pacing rate increment unit decreases the overdrive pacing rate by a determined rate decrement in response to detection of no more than one intrinsic heart beat within a second determined search period.

18. A method for controlling overdrive pacing of a patient'"'"'s heart using an implantable cardiac stimulation device connected to the heart, the method comprising the steps of:

determining an overdrive pacing rate;

overdrive pacing the heart at the overdrive pacing rate;

detecting intrinsic heart beats arising during the overdrive pacing; and

if at least two intrinsic heart beats are detected within a first determined search period, increasing the overdrive pacing rate by a determined rate increment; and

if no intrinsic heart beats are detected within a second determined search period, decreasing the overdrive pacing rate by a determined rate decrement.

19. The method of claim 18 wherein the first determined search period extends for a first determined number of overdrive paced cycles.

20. The method of claim 19 wherein the first determined search period begins with a first detected intrinsic beat.

21. The method of claim 20 wherein the first determined search period is between 8 and 40 cycles, inclusive.

22. The method of claim 18 wherein the step of varying the control values based on the actual degree of pacing includes the steps of:

inputting a target value representative of a target degree of pacing;

comparing the actual degree of pacing with the target degree of pacing; and

adjusting the control values to reduce a difference, if any, between the actual degree of pacing and the target degree of pacing.

23. The method of claim 22 wherein the first determined search period is 10 cycles.

24. The method of claim 18 wherein the second determined search period begins following an increase in the overdrive pacing rate.

25. The method of claim 24 wherein the second determined search period is between 8 and 40 cycles, inclusive.

26. The method of claim 18 wherein the determined rate increment is selected from a group including 5, 10, 15, 20, and 25 ppm.

27. The method of claim 18 wherein the determined rate decrement is selected from a group including 1, 2, 3, 4, and 5 ppm.

28. The method of claim 18 wherein the step of determining the overdrive pacing rate includes the steps of:

determining a sinus rate; and

setting the overdrive pacing rate to be equal to the sinus rate.

29. The method of claim 28 wherein the step of determining the sinus rate includes the steps of:

detecting at least three consecutive sinus P-waves;

determining an average interval between the P-waves; and

calculating the sinus rate based upon the average interval.

30. The method of claim 28 further including the step of periodically re-determining the overdrive pacing rate by:

suspending overdrive pacing;

detecting at least three consecutive P-waves while overdrive pacing is suspended;

determining an updated sinus rate based upon the at least three consecutive P-waves; and

setting the overdrive pacing rate based upon the updated sinus rate.

31. The method of claim 18 wherein the step of determining the overdrive pacing rate includes the steps of:

determining an atrial rate; and

setting the overdrive pacing rate to be equal to the atrial rate.

32. The method of claim 31 further including the steps of:

periodically determining an updated atrial rate;

comparing the updated atrial rate with a current overdrive pacing rate; and

if the updated atrial rate exceeds the current overdrive pacing rate by a determined amount, resetting the overdrive pacing rate to be equal to the updated atrial rate.