Glucose measurement utilizing non-invasive assessment methods
First Claim
1. A process for determining a glucose level of a human body, comprising the steps of:
- a.) cleaning a skin surface on said human body;
b.) achieving a non-induced static level of glucose at the skin surface as measured over a period of time, wherein the static level is correlateable to the glucose level of the human body; and
c.) measuring said skin surface glucose level.
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Accused Products
Abstract
This involves non-invasive glucose measurement processes for determining blood glucose level in the human body. After achieving a static level of glucose at a surface of the skin over some period of time, the glucose may then be measured by a variety of different processes. A sample of the glucose may also first be extracted from the skin and this sample may then be measured. Clearly, these processes are especially suitable for monitoring glucose levels in the human body, and is especially beneficial to users having diabetes mellitus. These procedures may be used for other analyte materials that are found in appropriate regions of the outer skin.
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Citations
17 Claims
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1. A process for determining a glucose level of a human body, comprising the steps of:
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a.) cleaning a skin surface on said human body;
b.) achieving a non-induced static level of glucose at the skin surface as measured over a period of time, wherein the static level is correlateable to the glucose level of the human body; and
c.) measuring said skin surface glucose level. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17)
a.) extracting a sample from the skin surface, and b.) measuring the glucose level from the sample.
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3. The process of claim 2, wherein the step of extracting is selected from the group consisting of blister suction, wick extraction, microdialysis extraction, iontophoretic extraction, sontophoretic extraction, and chemically enhanced extraction.
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4. The process of claim 1, wherein the step of measuring comprises electrochemical sensors.
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5. The process of claim 4, wherein the electrochemical sensors comprise glucose electrodes.
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6. The process of claim 1, wherein the step of measuring comprises optochemical sensors.
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7. The process of claim 6, wherein the optochemical sensors comprise colorimetric strips.
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8. The process of claim 1, wherein the step of measuring comprises near-infrared spectroscopy.
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9. The process of claim 1, wherein the step of measuring comprises Raman spectroscopy.
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10. The process of claim 1, wherein the step of measuring comprises photoacoustic spectroscopy.
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11. The process of claim 1, wherein the step of measuring comprises measuring a refractive index or scatter changes of the sample.
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12. The process of claim 1, wherein the step of measuring comprises fluorescent spectroscopy.
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13. The process of claim 1, wherein the step of measuring comprises polarization spectroscopy.
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14. The process of claim 1 wherein the period of time is less than six hours.
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15. The process of claim 1 wherein the period of time is less than one hour.
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16. The process of claim 1 wherein the period of time is less than ten minutes.
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17. The process of claim 1 wherein the period of time is less than five minutes.
Specification