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Microfluidic devices for the controlled manipulation of small volumes

DC
  • US 6,524,456 B1
  • Filed: 09/29/1999
  • Issued: 02/25/2003
  • Est. Priority Date: 08/12/1999
  • Status: Expired due to Term
First Claim
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1. A method of forming and transporting a series of minute volume segments of a material in a microchannel comprising the steps of:

  • a. providing a microchannel device having a first channel having an inlet end connected to a source of transport liquid and an outlet end and having a second channel having an inlet end connected to a source of segmenting liquid that is immiscible with the transport liquid and an outlet end interconnected with said first channel;

    b. drawing a volume of segmenting liquid into said first channel through said second channel;

    c. transporting the volume of segmenting liquid in said first channel toward said first channel outlet end; and

    then d. repeating steps b. and c. to form a series of discrete volumes of the segmenting liquid.

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