Radiation catheters optimized for stepped delivery technique

• US 6,527,692 B1
• Filed: 11/19/1999
• Issued: 03/04/2003
• Est. Priority Date: 11/19/1999
• Status: Expired due to Fees

• Current Assignee: Trustees Of Columbia University In The City Of New York (Columbia University)
• Original Assignee: Trustees Of Columbia University In The City Of New York (Columbia University)
• Inventors: Weinberger, Judah Z.
• Primary Examiner(s): Winakur, Eric F.
• Assistant Examiner(s): Veniaminov, Nikita R
• Application Number:
  US09/444,321
• Time in Patent Office: 1,201 Days
• Field of Search: 600/3, 600/5, 606/194, 606/15, 604/53
• US Class Current: 600/3
• CPC Class Codes: A61M 2025/1047 having centering means, e.g. balloons having an appropriate shape
• CPC Class Codes: A61M 2025/1061 having separate inflations tubes, e.g. coaxial tubes or tubes otherwise arranged apart from the catheter tube
• CPC Class Codes: A61M 25/1011 Multiple balloon catheters
• CPC Class Codes: A61N 2005/1003 having means for centering a radioactive source within the lumen, e.g. balloons
• CPC Class Codes: A61N 5/1002 Intraluminal radiation therapy

Abstract

A radiation catheter for intraluminal treatment of a patient has a plurality of separably inflatable and deflatable balloon segments located along the length of the catheter, and a radiation source within a lumen of the catheter. As the radiation source is moved, one or more balloon segments closest to the source is inflated with the remainder deflated thereby allowing blood to perfuse in areas where inflation of the segments is not needed to effect centering of the source in the luminal structure.

Claims

1. A radiation catheter for treating a luminal structure of a patient, comprising:

a catheter having at least one centrally disposed lumen adapted to center radioactive material in the luminal structure of the patient said lumen being open throughout its interior to receive a radioactive source;

a source of radioactive material; and

at least two balloon segments located at different longitudinal extents of the catheter, said segments being separably inflatable and deflatable.

2. The radiation catheter according to claim 1, further comprising a radiation source movable within the lumen of the catheter, wherein the balloon segment nearest the source is inflatable to center the radiation source radially in the luminal structure, and deflatable when not needed to center the radiation source.

3. The radiation catheter according to claim 1, wherein the balloon segments comprise a plurality of donut shaped or lobulated balloons.

4. The radiation catheter according to claim 1, wherein the balloon segments comprise segments of a balloon spirally wound around the catheter.

5. The radiation catheter according to claim 2, wherein the radiation source is a wire.

6. The radiation catheter according to claim 5, wherein the radiation source comprises radiation pellets mounted on the wire.

7. The radiation catheter according to claim 1, wherein the balloon segments are at least three, and wherein at least two adjacent segments are inflated at the same time.

8. The radiation catheter according to claim 1, wherein the balloon segments are mounted to the catheter.

9. The radiation catheter according to claim 1, further comprising a tube into which the catheter is slidably received, and where the balloon segments are mounted to the tube.

10. The radiation catheter according to claim 1, further including perfusion holes to permit fluid to flow inside the catheter around an inflated balloon segment.

11. A radiation catheter for treating a luminal structure of a patient, comprising:

a catheter having at least one centrally disposed lumen, said lumen being open throughout its interior to receive a radioactive source; and

at least two balloon segments located at different longitudinal extents of the catheter, said segments being separably inflatable and deflatable; and

a radiation source movable within the lumen of the catheter, whereby the balloon segment nearest the source is inflatable to center the radiation source radially in the luminal structure, and deflatable when not needed to center the radiation source.

12. The radiation catheter according to claim 11, wherein the balloon segments comprise a plurality of donut shaped or lobulated balloons.

13. The radiation catheter according to claim 11, wherein the balloon segments comprise segments of a balloon spirally wound around the catheter.

14. The radiation catheter according to claim 11, wherein the radiation source is a wire.

15. The radiation catheter according to claim 14, wherein the radiation source comprises radiation pellets mounted on the wire.

16. The radiation catheter according to claim 11, wherein the balloon segments are at least three, and wherein at least two adjacent segments are inflated at the same time.

17. The radiation catheter according to claim 11, wherein the balloon segments are mounted to the catheter.

18. The radiation catheter according to claim 11, further comprising a tube into which the catheter is slidably received, and where the balloon segments are mounted to the tube.

19. The radiation catheter according to claim 11, further including perfusion holes to permit fluid to flow inside the catheter around an inflated balloon segment.