Device and method for laser biomodulation in PDT/surgery

• US 6,527,764 B1
• Filed: 12/02/1999
• Issued: 03/04/2003
• Est. Priority Date: 12/02/1999
• Status: Expired due to Fees

• Current Assignee: Biolitec Pharma Marketing Ltd.
• Original Assignee: CeramOptec Industries Incorporated (Biolitec AG)
• Inventors: Neuberger, Wolfgang, Spaniol, Stefan
• Primary Examiner(s): Dvorak, Linda C. M.
• Assistant Examiner(s): FARAH, AHMED M
• Application Number:
  US09/453,338
• Time in Patent Office: 1,188 Days
• Field of Search: 606/3, 606/7-10, 606/13-16, 607/88, 607/89, 385/15, 385/53, 385/76, 385/88-92, 385/126-128
• US Class Current: 606/10
• CPC Class Codes: A61B 2018/208 with multiple treatment beams not sharing a common path, e.g. non-axial or parallel
• CPC Class Codes: A61N 2005/0644 Handheld applicators
• CPC Class Codes: A61N 5/0616 Skin treatment other than tanning
• CPC Class Codes: A61N 5/062 Photodynamic therapy, i.e. excitation of an agent
• CPC Class Codes: A61N 5/067 using laser light

Abstract

The present invention provides a device and method for a laser treatment that couples surgical or activating laser power with a biomodulating power to enhance proper tissue healing and regeneration after treatment. This treatment is achieved using an optical fiber system delivering laser power from two separate laser sources. One source provides laser energy at a power level and density suitable for the surgical or activation action desired. The second source produces laser power at a wavelength suitable for producing biomodulating effects in the treated tissue. Biomodulation treatment of the tissue promotes cellular healing and regeneration and ensures that proper healing occurs. In addition, the present invention describes a method by which the device is used for treatment. The surgical or activating laser energy is applied to a site as the device is passed over the treatment area. During this treatment, the device also emits a biomodulating treatment beam onto the site over which the first beam has already passed. The device in this manner systematically performs a surgical or activation action and then follows immediately with a healing action, enhancing the success of the treatment by ensuring that the treated tissue heals quickly and properly.

Claims

1. A laser delivery system combining delivery of a primary surgical/activating laser energy and of a lower power biomodulating laser energy, aimed at biostimulating/biosupressing cellular proliferation as required at a treatment site to enhance wound healing comprising:

at least two distinct laser sources;

a first laser source emitting high-power laser energy for performing laser surgical/activation functions;

a second laser source emitting a low-power laser energy for performing biomodulating functions including biostimulation, biosupression and immunostimulation;

a first optical fiber and a second optical fiber, each having a proximal end and a distal end;

an optical coupler with an input end and an output end;

wherein said first optical fiber'"'"'s proximal end is optically connected to said first laser source and said first optical fiber'"'"'s distal end is optically connected to said optical coupler'"'"'s input end, and wherein said second optical fiber'"'"'s proximal end is optically connected to said second laser source and said second optical fiber'"'"'s distal end is optically connected to said optical coupler'"'"'s input end;

an optical output structure with a proximal end and a distal end;

passing through a hand piece;

wherein said hand piece maintains a fixed orientation of said optical output structure during treatment; and

wherein said high-power laser energy passing through said first optical fiber is coupled to said proximal end of said output structure at said output end of said optical coupler and said low-power laser energy passing through said second optical fiber is coupled to said proximal end of said output structure at said output end of said optical coupler, and wherein said high power energy and low power energy have independent/exclusive optical paths to said distal end of said output structure, from which high power and low power energy beams are projected.

2. A laser delivery system according to claim 1, wherein said optical output structure is a multi-core optical fiber having a first core set off center in said multi-core optical fiber, delivering high-power laser energy, and a second core set off center in said multi-core optical fiber, delivering low-power laser energy.

3. A laser delivery system according to claim 1, wherein said optical output structure is a multi-core optical fiber having a first core set centrally in said multi-core optical fiber, delivering high-power laser energy, and multiple peripheral cores optically coupled through said optical coupler to deliver said second source'"'"'s low-power laser energy.

4. A laser delivery system according to claim 2, wherein said first core is surrounded by a first core cladding layer and said second core is surrounded by a second core cladding layer.

5. A laser delivery system according to claim 3, wherein said first core is surrounded by a first core cladding layer and said multiple peripheral cores are each individually surrounded by a second core cladding layer.

6. A laser delivery system according to claim 1, wherein said optical output structure is comprised of at least two optical fibers oriented in a fixed manner relative to each other, in which a first fiber is optically coupled to said output of said first laser and said second fiber(s) is optically coupled to said output of said second laser.

7. A laser delivery system according to claim 1, wherein said low-power laser energy, from said second laser source, is emitted at 635 nm for optimal biostimulating effects.

8. A treatment method for a low-power biomodulation and in the same application effecting a high-power laser surgical/activation procedure comprising the steps of:

orienting an optical output structure such that said high-power surgical or activation laser energy is aimed at a treatment site;

orienting said optical output structure such that said low-power biomodulating laser energy is aimed at said treatment site;

moving said optical output structure parallel to a skin surface along said treatment area; and

positioning said optical output structure during application such that said high-power laser energy is generally first administered to said treatment site, followed by said low-power laser energy.

9. A treatment method according to claim 8, wherein said low-power laser energy is emitted circumferentially around said high-power laser energy such that positioning of said low-power laser energy relative to said high-power laser energy is fixed at any orientation.