Uniform drug delivery therapy
First Claim
Patent Images
1. A dosage form for the delivery of a drug, wherein the dosage form comprises:
- (a) a drug composition;
(b) a dose of drug comprising a size of less than 150 μ
m in the drug composition;
(c) a hydrophilic polymer comprising a size of less than 250 μ
m in the drug composition;
(d) a coat that surrounds the drug composition comprising means for delaying release of drug from the drug composition;
(e) a wall comprising a composition that surrounds the coat; and
(f) means in the dosage form for delivering the drug from the dosage form;
wherein said drug is verapamil hydrochloride; and
wherein the dosage form releases said verapamil hydrochloride at a rate having a percentage deviation of not more than 5% from the mean release rate over a prolonged period of time.
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Abstract
The invention disclosed pertains to a novel delivery system comprising an agent formulation and means for dispensing the agent formulation from the delivery system.
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Citations
1 Claim
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1. A dosage form for the delivery of a drug, wherein the dosage form comprises:
-
(a) a drug composition;
(b) a dose of drug comprising a size of less than 150 μ
m in the drug composition;
(c) a hydrophilic polymer comprising a size of less than 250 μ
m in the drug composition;
(d) a coat that surrounds the drug composition comprising means for delaying release of drug from the drug composition;
(e) a wall comprising a composition that surrounds the coat; and
(f) means in the dosage form for delivering the drug from the dosage form;
wherein said drug is verapamil hydrochloride; and
wherein the dosage form releases said verapamil hydrochloride at a rate having a percentage deviation of not more than 5% from the mean release rate over a prolonged period of time.
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Specification
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Current AssigneeE.P. Ltd.
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Original AssigneeALZA Corporation (Johnson & Johnson)
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InventorsMagruder, Judy A., Lam, Andrew, Hamel, Lawrence G., Wong, Patrick S. L., Ayer, Atul D.
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Primary Examiner(s)Page, Thurman K.
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Assistant Examiner(s)Seidleck, Brian K.
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Application NumberUS09/602,916Time in Patent Office998 DaysField of Search424/464, 424/468, 424/469, 424/470, 424/473, 514/523, 514/964, 604/890.1, 604/892.1US Class Current424/473CPC Class CodesA61K 9/0004 Osmotic delivery systems; S...
