Kits for early detection of heart disease
First Claim
1. A kit for detecting a condition which causes heart disease in a mammal, the kit comprising a composition for detecting a level of at least one non-polypeptidic cardiac marker in a test sample obtained from said mammal, wherein said kit is able to determine if said level of said non-polypeptidic cardiac marker in said test sample correlates with said condition that causes heart disease in a mammal wherein said marker is selected from the group consisting of sphingolipid, sphingosine, sphingosine-1-phosphate, dihydrosphingosine and sphingosylphosphorylcholine.
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Abstract
The invention relates to methods, compositions, kits, and devices for detecting cardiac ischemia, hypoxia, or other causes of heart failure in a mammal by obtaining a test sample from a mammal, measuring a level of a non-polypeptidic cardiac marker in the test sample, and determining if the level of the cardiac marker measured in said test sample correlates with cardiac ischemia or hypoxia or another form of heart failure.
213 Citations
16 Claims
- 1. A kit for detecting a condition which causes heart disease in a mammal, the kit comprising a composition for detecting a level of at least one non-polypeptidic cardiac marker in a test sample obtained from said mammal, wherein said kit is able to determine if said level of said non-polypeptidic cardiac marker in said test sample correlates with said condition that causes heart disease in a mammal wherein said marker is selected from the group consisting of sphingolipid, sphingosine, sphingosine-1-phosphate, dihydrosphingosine and sphingosylphosphorylcholine.
Specification