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Surgically implanted devices having reduced scar tissue formation

  • US 6,534,693 B2
  • Filed: 01/31/2001
  • Issued: 03/18/2003
  • Est. Priority Date: 11/06/2000
  • Status: Expired due to Term
First Claim
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1. A sheet of material adapted for implantation between tissues of a human body, the sheet of material including an attached anti-proliferative drug, the anti-proliferative drug being designed to reduce the generation of scar tissue, the anti-proliferative drug being selected from the group consisting of Rapamycin, taclolimus (FK506), and one of the following analogs of sirolimus:

  • SDZ-RAD, CCI-779, 7-epi-rapamycin, 7-thiomethyl-rapamycin, 7-epi-trimethoxyphenyl-rapamycin, 7-epi-thiomethyl-rapamycin, 7-demethoxy-rapamycin, 32-demethoxy, 2-desmethyl and proline.

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