Device and method for noninvasive continuous determination of physiologic characteristics
First Claim
1. A device for the noninvasive monitoring of a physiologic characteristic of a patient'"'"'s blood, comprising:
- a tissue probe having a first radiation emitter with a first wavelength and a first radiation detector configured to receive the first wavelength after absorbance through the patient'"'"'s blood;
a position sensor for determining the relative height compared to a level corresponding to the patient'"'"'s heart; and
a controller for computing the physiologic characteristic of the patient'"'"'s blood based on pulse wave amplitude calculated from the absorbance of the first wavelength of radiation and the relative height of the probe.
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Abstract
The invention comprises devices and methods for the noninvasive monitoring of a physiologic characteristic of a patient'"'"'s blood, such as blood pressure. One embodiment is a tissue probe combined with a position sensor for determining the relative height of the probe compared to a level corresponding to the patient'"'"'s heart. Alternatively, the tissue probe can be combined with a movement generator for inducing a height change of the probe with respect to patient'"'"'s heart. By measuring absorbance characteristics of the blood at varying positions relatively to the level of the patient'"'"'s heart, characteristics such as arterial and central venous blood pressure and cardiac output can be determined. In yet another embodiment, two probes are used to compute pulse delays between coupled tissues or opposing tissues. Measuring delays in pulse arrival times in coupled organs or members on opposite sides of the body allows the determination of various physiological characteristics.
211 Citations
23 Claims
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1. A device for the noninvasive monitoring of a physiologic characteristic of a patient'"'"'s blood, comprising:
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a tissue probe having a first radiation emitter with a first wavelength and a first radiation detector configured to receive the first wavelength after absorbance through the patient'"'"'s blood;
a position sensor for determining the relative height compared to a level corresponding to the patient'"'"'s heart; and
a controller for computing the physiologic characteristic of the patient'"'"'s blood based on pulse wave amplitude calculated from the absorbance of the first wavelength of radiation and the relative height of the probe. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. A device for the noninvasive monitoring of a physiologic characteristic of a patient'"'"'s blood, comprising:
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a tissue probe having a first radiation emitter with a first wavelength and a first radiation detector configured to receive the first wavelength after absorbance through the patient'"'"'s blood secured to a desired portion of the patient'"'"'s tissue;
a movement generator for inducing a position change of the probe with respect to a level corresponding to the patient'"'"'s heart; and
a controller for computing the physiologic characteristic of the patient'"'"'s blood based on the absorbance of the first wavelength of radiation and the relative position of the probe. - View Dependent Claims (9, 10, 11, 12)
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13. A method for noninvasively determining a physiological characteristic of a patient'"'"'s blood comprising the steps of:
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providing a tissue probe having a first radiation emitter with a first wavelength and a first radiation detector configured to receive the first wavelength after absorbance through the patient'"'"'s blood;
measuring absorbance of the patient'"'"'s blood by emitting a first radiation through the patient'"'"'s blood and detecting the radiation after passage through the patient'"'"'s blood with the probe at a first position relative to a level corresponding to the patient'"'"'s heart;
computing a blood parameter at the first position based on the absorbance;
moving the probe relative to a level corresponding to the patient'"'"'s heart to a second position;
measuring absorbance at the second position;
computing the blood parameter based on the absorbance at the second position; and
determining the physiological characteristic by comparing the absorbance at the first and second position. - View Dependent Claims (14, 15, 16, 17)
computing the hydrostatic pressure difference between the first and second position; and
performing self-calibration based upon the hydrostatic pressure difference.
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15. The method of claim 13, further comprising the steps of:
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computing the hydrostatic pressure difference between the first and second position;
comparing the blood parameter to the hydrostatic pressure difference; and
deriving a mathematical function relating hydrostatic pressure to the blood parameter.
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16. The method of claim 15, wherein the physiological characteristic comprises arterial blood pressure.
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17. The method of claim 15, wherein the blood parameter is selected from the group consisting of pulse amplitude, pulse delay, pulse velocity and pulse contour.
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18. A method for noninvasively determining a physiological characteristic of a patient'"'"'s blood comprising the steps of:
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providing a first tissue probe having a first radiation emitter with a first wavelength and a first radiation detector configured to receive the first wavelength after absorbance through the patient'"'"'s blood;
providing a second tissue probe having a second radiation emitter with a second wavelength and a second radiation detector configured to receive the second wavelength after absorbance through the patient'"'"'s blood;
positioning the first and second probes at coupled tissue locations on the patient;
measuring absorbance of the patient'"'"'s blood at the coupled tissue locations by emitting radiation through the patient'"'"'s blood and detecting the radiation after passage through the patient'"'"'s blood;
determining a blood parameter by comparing absorbance at the coupled tissue locations; and
computing the physiological characteristic of the patient'"'"'s blood. - View Dependent Claims (19)
measuring blood pressure;
determining the pulse delay by comparing absorbance at the coupled tissue locations;
estimating the pulse distance differential; and
computing pulse velocity from pulse distance and pulse delay.
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20. A method for noninvasively determining a physiological characteristic of a patient'"'"'s blood comprising the steps of:
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providing a first tissue probe having a first radiation emitter with a first wavelength and a first radiation detector configured to receive the first wavelength after absorbance through the patient'"'"'s blood;
providing a second tissue probe having a second radiation emitter with a second wavelength and a second radiation detector configured to receive the second wavelength after absorbance through the patient'"'"'s blood;
positioning the first and second probes at opposing locations on the patient;
measuring absorbance of the patient'"'"'s blood at the opposing locations by emitting radiation through the patient'"'"'s blood and detecting the radiation after passage through the patient'"'"'s blood;
determining a blood parameter by comparing absorbance at the locations; and
computing the physiological characteristic of the patient'"'"'s blood. - View Dependent Claims (21)
measuring blood pressure;
determining the pulse delay by comparing absorbance at the opposing locations;
estimating the pulse distance differential; and
computing pulse velocity from pulse distance and pulse delay.
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22. A method for noninvasively determining a physiological characteristic of a patient'"'"'s blood comprising the steps of:
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providing a first tissue probe having a first radiation emitter with a first wavelength and a first radiation detector configured to receive the first wavelength after absorbance through the patient'"'"'s blood;
providing a second tissue probe having a second radiation emitter with a second wavelength and a second radiation detector configured to receive the second wavelength after absorbance through the patient'"'"'s blood;
positioning the first and second probes at locations on the patient;
measuring absorbance of the patient'"'"'s blood at the first and second probe locations by emitting radiation through the patient'"'"'s blood and detecting the radiation after passage through the patient'"'"'s blood;
determining a blood parameter by comparing absorbance at the locations;
moving the first probe relative to a level corresponding to the patient'"'"'s heart to a second position;
measuring absorbance at the second position;
computing the blood parameter based on the absorbance at the second position; and
determining the physiological characteristic by comparing the absorbance at the first and second position and the absorbance at the first and second probes. - View Dependent Claims (23)
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Specification