Endoluminal implantable devices and method of making same

• US 6,537,310 B1
• Filed: 03/20/2000
• Issued: 03/25/2003
• Est. Priority Date: 11/19/1999
• Status: Expired due to Term

• Current Assignee: Vactronix Scientific, LLC
• Original Assignee: Advanced Bio Prosthetic Surfaces, Ltd.
• Inventors: Banas, Christopher E., Palmaz, Julio C., Wiseman, Roger W., Marton, Denes, Boyle, Christopher T.
• Primary Examiner(s): TRUONG, KEVIN THAO
• Application Number:
  US09/532,164
• Time in Patent Office: 1,100 Days
• Field of Search: 623/1.13, 623/1.15, 623/1.18, 623/1.19, 623/1.32, 623/1.44, 623/1.46, 128/898, 606/191, 606/198
• US Class Current: 623/1.13
• CPC Class Codes: A61F 2/0077 Special surfaces of prostheses, e.g. for improving ingrowth A61F2/30767 takes precedence
• CPC Class Codes: A61F 2/07 Stent-grafts
• CPC Class Codes: A61F 2/82 Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents stent-grafts for tubular structures of the body other than blood vessels A61F2/04; stent-grafts for blood vessels A61F2/07; instruments specially adapted for placement or removal of stents or stent-grafts A61F2/95; for closing wounds, or holding wounds closed A61B17/04 - A61B17/115; dilators A61M29/00
• CPC Class Codes: A61F 2/90 characterised by a net-like or mesh-like structure
• CPC Class Codes: A61F 2/91 made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
• CPC Class Codes: A61F 2/915 with bands having a meander structure, adjacent bands being connected to each other
• CPC Class Codes: A61F 2002/0086 for preferentially controlling or promoting the growth of specific types of cells or tissues
• CPC Class Codes: A61F 2002/072 Encapsulated stents, e.g. wire or whole stent embedded in lining
• CPC Class Codes: A61F 2002/91541 Adjacent bands are arranged out of phase
• CPC Class Codes: A61F 2002/9155 Adjacent bands being connected to each other
• CPC Class Codes: A61F 2220/0041 using additional screws, bolts, dowels or rivets, e.g. connecting screws
• CPC Class Codes: A61F 2220/005 using adhesives
• CPC Class Codes: A61F 2220/0058 soldered or brazed or welded
• CPC Class Codes: A61F 2220/0075 sutured, ligatured or stitched, retained or tied with a rope, string, thread, wire or cable
• CPC Class Codes: A61L 27/04 Metals or alloys
• CPC Class Codes: A61L 27/3679 Hollow organs, e.g. bladder, esophagus, urether, uterus, intestine
• CPC Class Codes: A61L 27/507 for artificial blood vessels apparatus for applying cells on a blood vessel prosthesis A61F2/062
• CPC Class Codes: A61L 31/022 Metals or alloys
• CPC Class Codes: Y10T 29/49936 Surface interlocking

Abstract

An implantable endoluminal device that is fabricated from materials that present a blood or body fluid and tissue contact surface that has controlled heterogeneities in material constitution. An endoluminal stent-graft and web-stent that is made of an monolithic material deposited into a monolayer and etched into regions of structural members and web regions subtending interstitial regions between the structural members. An endoluminal graft is also provided which is made of a biocompatible metal or metal-like material. The endoluminal stent-graft is characterized by having controlled heterogeneities in the stent material along the blood flow surface of the stent and the method of fabricating the stent using vacuum deposition methods.

Claims

1. A method of manufacturing an endoluminal stent-graft capable of radially expanding from a first diameter to a second diameter, comprising the steps of:

a. providing a substrate having an exterior surface capable of accommodating metal deposition thereupon;

b. depositing a stent-forming metal onto the substrate by a vacuum deposition method;

c. etching regions into the deposited stent-forming metal to form differentiated plurality of structural members and plurality of web regions between the adjacent pairs of the structural members; and

d. removing the substrate from the endoluminal stent formed thereupon.

2. The method according to claim 1, wherein step (a) further comprises the step of imparting a pattern onto the exterior surface of the substrate.

3. The method according to claim 1, wherein step (b) further comprises the step of depositing the stent-forming metal onto the pattern onto the substrate.

4. The method according to claim 2, further comprises the step of depositing a sacrificial layer of a material onto the substrate prior to step (b).

5. The method according to claim 2, wherein step (b) is conducted by ion beam-assisted evaporative deposition.

6. The method according to claim 2, wherein step (b) is conducted by sputtering.

7. The method according to claim 2, wherein the substrate is a cylindrical substrate.

8. The method according to claim 2, wherein the substrate is a planar substrate.

9. The method according to claim 8, wherein the inert gas is selected from the group consisting of argon, xenon, nitrogen and neon.