Tissue cutting/tissue removing device with vacuum feature

• US 6,540,761 B2
• Filed: 03/12/2001
• Issued: 04/01/2003
• Est. Priority Date: 01/23/1995
• Status: Expired due to Term

• Current Assignee: CardioVascular Technologies, Inc.
• Original Assignee: Russell A. Houser
• Inventors: Houser, Russell A.
• Primary Examiner(s): KENNEDY, SHARON E
• Application Number:
  US09/804,009
• Publication Number:
  US 20020013580A1
• Time in Patent Office: 750 Days
• Field of Search: 604/22, 606/37-41, 606/45-50, 606/159, 606/167, 606/170, 606/171, 606/180
• US Class Current: 606/170
• CPC Class Codes: A61B 18/1492 having a flexible, catheter-like structure, e.g. for heart ablation A61B18/1477 takes precedence
• CPC Class Codes: A61B 2018/00601 Cutting
• CPC Class Codes: A61B 2018/1861 with an instrument inserted into a body lumen or cavity, e.g. a catheter
• CPC Class Codes: A61B 2218/007 Aspiration

Abstract

A tissue cutting device includes a catheter with a window at its distal tip for admitting tissue into a catheter compartment. A cylindrical cartridge in the compartment has a cutting edge that supports an electrically conductive cutting element, e.g. a band or wire. The cutting element and adjacent tissue can be heated to a selected temperature by generating an electrical current through the cutting element. The catheter is maneuverable to position its distal end near the tissue to be cut. The catheter incorporates a vacuum feature that urges tissue into the compartment prior to cutting or severing and assists in holding the tissue during the cutting or severing process. Then, the cartridge is manipulated from the catheter'"'"'s proximal end to move the cutting edge across the window, cutting the tissue. According to alternative embodiments, the cartridge is either rotated or moved axially relative to the catheter and, in either event may be capable of closing the catheter window when the cut is complete. Further alternatives involve either placing an indifferent electrode on the patient and providing an RF signal via a single conductor to the cutting element for ohmic heating, or providing an RF (or a DC) current through the cutting element and two separate conductors for direct resistive heating of the cutting element. Additional feature of the device include therapeutic infusion before, during or after the cut.

Claims

1. A device for cutting tissue including:

an elongate catheter having a proximal end and a distal end, a catheter wall defining a compartment within the catheter, a window through the catheter wall open to the compartment, and at least one lumen passing between a first opening in the proximal end and a second opening in the compartment, the first opening being connected to a vacuum source;

a cartridge at least partially disposed within the compartment, said cartridge having a cutting edge with a cutting element disposed along the cutting edge, and an energy source operatively coupled to the cutting element, the cartridge being operable to urge tissue into the compartment when the first opening is connected to the vacuum source; and

a controller coupled to the cartridge and operable to selectively position and move the cartridge relative to the catheter and thereby provide a controlled movement of the cutting edge along the window.

2. The device of claim 1 wherein the second opening is distal to the window in the catheter wall.

3. The device of claim 1 wherein the second opening is proximal to the window in the catheter wall.

4. The device of claim 1 wherein the second opening is positioned to be open to the compartment.

5. The device of claim 1 wherein a drive tube couples the controller to the cartridge.

6. The device of claim 5 wherein the drive tube includes a lumen having an opening in the compartment and the lumen is configured to be connected to the vacuum source.

7. The device of claim 5 wherein the drive tube is positioned in the lumen.

8. The device of claim 1 wherein the catheter is maneuverable to locate the window against a tissue wall segment and the cutting edge is configured to cut tissue when vacuum is applied to the window.

9. The device of claim 8 wherein the application of vacuum from the vacuum source to the window when the window is located against the tissue wall segment causes the application of vacuum to at least the tissue wall segment.

10. The device of claim 1 further comprising a second lumen passing between a first opening in the proximal end and a second opening in the distal end.

11. The device of claim 10 further comprising a fluid source connected to the first opening of the second lumen.

12. The device of claim 11 wherein the fluid source comprises a therapeutic agent.

13. The device of claim 11 wherein the fluid source comprises a contrast agent.

14. The device of claim 1 wherein the cutting element is configured to heat tissue adjacent to the cutting edge.

15. The device of claim 1 wherein the cutting element is configured to heat tissue adjacent the cutting edge.

16. A tissue cutting system comprising:

a tissue cutting device comprising;

an elongate catheter having a proximal end and a distal end, a catheter wall defining a compartment within the catheter, a window through the catheter wall open to the compartment, a first lumen passing between a first opening in the proximal end and a first opening in the compartment, and a second lumen passing between a second opening in the proximal end and a second opening in the compartment,

a cartridge at least partially disposed within the compartment, said cartridge having a cutting edge with a cutting element disposed along the cutting edge, and an energy source operatively coupled to the cutting element, and

a controller coupled to the cartridge and operable to selectively position and move the cartridge relative to the catheter and thereby provide a controlled movement of the cutting edge along the window, wherein the catheter is maneuverable to locate the window against a tissue wall segment;

a vacuum source connectable to the first lumen; and

a fluid source connectable to the second lumen, wherein the cartridge is operable to urge tissue into the compartment when the first lumen is connected to the vacuum source.

20. The tissue cutting system of claim 16 wherein the cutting element is configured to heat tissue adjacent the cutting edge.

17. A method of cutting tissue, the method comprising:

providing a tissue cutting device comprising;

an elongate catheter having a proximal end and a distal end, a catheter wall defining a compartment within the catheter, a window through the catheter wall open to the compartment, and a first lumen passing between a first opening in the proximal end and a first opening in the compartment,

a cartridge at least partially disposed within the compartment, said cartridge having a cutting edge with a cutting element disposed along the cutting edge, and an energy source operatively coupled to the cutting element, and

a controller coupled to the cartridge and operable to selectively position and move the cartridge relative to the catheter and thereby provide a controlled movement of the cutting edge along the window, a drive tube coupling the controller to the cartridge, the drive tube including a second lumen having an opening in the compartment and being configured to be connected to a vacuum source, wherein the catheter is maneuverable to locate the window against a tissue wall segment;

connecting a vacuum source to one of the first lumen and the second lumen;

applying a vacuum to the tissue cutting device, wherein the cartridge is operable to urge tissue into the compartment when one of the first lumen and the second lumen is connected to the vacuum source;

connecting a fluid source to the other of the first lumen and the second lumen; and

applying a fluid to the tissue cutting device to supply the fluid to the tissue.

18. The method of cutting tissue of claim 17 wherein the fluid comprises a gene therapy agent.

19. The method of claim 17 further comprising heating tissue adjacent the cutting edge.