Inflatable catheter for selective organ heating and cooling and method of using the same
First Claim
Patent Images
1. A catheter method of changing the temperature of blood by heat transfer to or from a circulating working fluid, comprising:
- inserting an inflatable heat transfer element formed by at least an inlet lumen and an inflatable outlet lumen into an artery or vein;
inflating the inflatable heat transfer element by delivering a circulating working fluid to the inlet lumen of the inflatable heat transfer element, the temperature of the circulating working fluid different from that of the blood such that blood contacts both the inlet lumen and the outlet lumen; and
inducing turbulence in the working fluid by passing the working fluid through a helical turbulence-inducing path formed by the outlet lumen when inflated, and, inducing turbulence in blood flowing past the helical turbulence inducing path formed by the outlet lumen when inflated thereby enhancing heat transfer between the circulating working fluid and the blood.
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Abstract
A catheter system and method are provided which change the temperature of a fluid, such as blood, by heat transfer. Selective cooling or heating of an organ may be performed by changing the temperature of the blood feeding the organ. The catheter system includes an inlet lumen and an outlet lumen structured and arranged to carry a working fluid having a temperature different from the adjacent blood. The outlet lumen is configured to induce turbulence in the adjacent fluid passing adjacent the outlet lumen.
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Citations
70 Claims
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1. A catheter method of changing the temperature of blood by heat transfer to or from a circulating working fluid, comprising:
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inserting an inflatable heat transfer element formed by at least an inlet lumen and an inflatable outlet lumen into an artery or vein;
inflating the inflatable heat transfer element by delivering a circulating working fluid to the inlet lumen of the inflatable heat transfer element, the temperature of the circulating working fluid different from that of the blood such that blood contacts both the inlet lumen and the outlet lumen; and
inducing turbulence in the working fluid by passing the working fluid through a helical turbulence-inducing path formed by the outlet lumen when inflated, and, inducing turbulence in blood flowing past the helical turbulence inducing path formed by the outlet lumen when inflated thereby enhancing heat transfer between the circulating working fluid and the blood. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9)
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10. A catheter method of changing the temperature of blood by heat transfer to or from a circulating working fluid, comprising:
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inserting an inflatable heat transfer element formed by at least an inlet lumen and an inflatable outlet lumen into a flow of blood in an artery or vein; and
inflating the inflatable heat transfer element by delivering a working fluid having a temperature different than the blood temperature to an interior of the inlet lumen of the inflatable heat transfer element, the outlet lumen of the inflatable heat transfer element having a helical or spiral turbulence-inducing shape when inflated, blood such that blood contacts both the inlet lumen and the outlet lumen, and such that turbulence is induced in a substantial portion of a free stream of blood by contact with both the helical or spiral turbulence-inducing shape of the outlet lumen and the inlet lumen.
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11. A method of changing the temperature of blood, comprising:
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providing an inflatable heat transfer element, the inflatable heat transfer element formed by at least an inlet lumen and an outlet lumen, at least one of the inlet lumen or the outlet lumen having a turbulence-inducing shape;
inserting the inflatable heat transfer element into a blood vessel;
delivering a circulating working fluid from a working fluid supply to the inflatable heat transfer element, the temperature of the circulating working fluid different from that of the blood;
inflating the inflatable heat transfer element with the circulating working fluid;
inducing turbulence in the working fluid or in the blood by circulating the working fluid through the lumen having the turbulence-inducing shape, thereby enhancing heat transfer between the circulating working fluid and the blood; and
returning the working fluid to the working fluid supply via the outlet lumen. - View Dependent Claims (12, 13)
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14. A method of changing the temperature of blood, comprising:
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providing an inflatable heat transfer element having a turbulence-enhancing shape such that the inflatable heat transfer element is formed by at least an inlet lumen and an outlet lumen, at least one of the inlet lumen or the outlet lumen having a shape of a helix;
inserting the inflatable heat transfer element into a blood vessel;
delivering a circulating working fluid from a working fluid supply to the inflatable heat transfer element, the temperature of the circulating working fluid different from that of the blood;
inflating the inflatable heat transfer element with the circulating working fluid;
inducing turbulence in the working fluid or in the blood by circulating the working fluid through the lumen having the turbulence-inducing shape, thereby enhancing heat transfer between the circulating working fluid and the blood; and
returning the working fluid to the working fluid supply via the outlet lumen.
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15. A method of changing the temperature of blood, comprising:
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providing an inflatable heat transfer element having a turbulence-enhancing shape such that the inflatable heat transfer element is formed by at least an inlet lumen and an outlet lumen, at least one of the inlet lumen or the outlet lumen having a shape of a spiral;
inserting the inflatable heat transfer element into a blood vessel;
delivering a circulating working fluid from a working fluid supply to the inflatable heat transfer element, the temperature of the circulating working fluid different from that of the blood;
inflating the inflatable heat transfer element with the circulating working fluid;
inducing turbulence in the working fluid or in the blood by circulating the working fluid through the lumen having the turbulence-inducing shape, thereby enhancing heat transfer between the circulating working fluid and the blood; and
returning the working fluid to the working fluid supply via the outlet lumen.
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16. A method of changing the temperature of blood, comprising:
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providing an inflatable heat transfer element, the inflatable heat transfer element formed by at least an inlet lumen and an outlet lumen, at least one of the inlet lumen or the outlet lumen having a turbulence-enhancing shape such that one lumen helically encircles the other;
inserting the inflatable heat transfer element into a blood vessel;
delivering a circulating working fluid from a working fluid supply to the inflatable heat transfer element, the temperature of the circulating working fluid different from that of the blood;
inflating the inflatable heat transfer element with the circulating working fluid;
inducing turbulence in the working fluid or in the blood by circulating the working fluid through the lumen having the turbulence-inducing shape, thereby enhancing heat transfer between the circulating working fluid and the blood; and
returning the working fluid to the working fluid supply via the outlet lumen. - View Dependent Claims (17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31)
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32. A method of changing the temperature of blood, comprising:
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providing an inflatable heat transfer element having a longitudinal axis, the inflatable heat transfer element formed by at least an inlet lumen and an outlet lumen, the inlet and outlet lumens at least partially coaxial, at least one of the inlet lumen or the outlet lumen having a turbulence-enhancing shape such that the radius of the inlet or outlet lumen varies with respect to position along the axis;
inserting the inflatable heat transfer element into a blood vessel;
delivering a circulating working fluid from a working fluid supply to the inflatable heat transfer element, the temperature of the circulating working fluid different from that of the blood;
inflating the inflatable heat transfer element with the circulating working fluid;
inducing turbulence in the working fluid or in the blood by circulating the working fluid through the lumen having the turbulence-inducing shape, thereby enhancing heat transfer between the circulating working fluid and the blood; and
returning the working fluid to the working fluid supply via the outlet lumen.
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33. A method of changing the temperature of blood, comprising:
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providing an inflatable heat transfer element, the inflatable heat transfer element formed by at least an inlet lumen and an outlet lumen, at least one of the inlet lumen or the outlet lumen having a turbulence-inducing shape and configured to cause two counter-rotating flows to develop in the circulating working fluid;
inserting the inflatable heat transfer element into a blood vessel;
delivering a circulating working fluid from a working fluid supply to the inflatable heat transfer element, the temperature of the circulating working fluid different from that of the blood;
inflating the inflatable heat transfer element with the circulating working fluid;
inducing turbulence in the working fluid or in the blood by circulating the working fluid through the lumen having the turbulence-inducing shape, thereby enhancing heat transfer between the circulating working fluid and the blood; and
returning the working fluid to the working fluid supply via the outlet lumen.
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34. A catheter method of changing the temperature of blood by heat transfer, comprising:
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inserting a heat transfer element formed by at least an inlet lumen and an inflatable outlet lumen into an artery or vein;
delivering a circulating working fluid to the heat transfer element, the temperature of the working fluid different from that of the blood; and
passing the circulating working fluid through a helical path formed by the outlet lumen, such that the helical return path enhances the heat transfer between the working fluid and the blood by causing turbulence therein. - View Dependent Claims (35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70)
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Specification