Method for determining concentration of an analyte in a test strip
First Claim
1. A method for measuring an analyte in a fluid sample in a meter system, comprising:
- initiating a measuring period for a fluid sample;
measuring a property of the fluid sample at each of n points in time, said points in time being spaced at predetermined intervals to form a sequence of n measurement values, where n is an integer;
comparing two nonconsecutive measurement values to determine at least one ratio;
terminating the measuring of the fluid sample when at least one of said at least one ratio meets predetermined criteria indicating a final analyte value can be accurately determined; and
determining a final analyte value based on said measurement values.
10 Assignments
0 Petitions
Accused Products
Abstract
The present invention provides a method of measuring an analyte, such as glucose in a fluid sample, such as whole blood, by a reflectance reading device. The method includes making periodic intermediate calculations of analyte level and dynamically ascertaining when an analytical reaction has reached an end point. Once stable, the process stops making periodic calculations and reports the final, actual glucose concentration. According to an exemplary embodiment, the method is performed by a reflectance photometer using an analytical test strip containing reagents that react with an analyte of interest in the test fluid. The end point is determined by calculating an intermediate analyte level of the testing element at predetermined intervals and calculating a ratio value corresponding to the (n)th measurement to an (n-5)th measurement. When two consecutive ratio values are less than or equal to a predetermined value, the end point is deemed reached and the final analyte level ascertained.
-
Citations
36 Claims
-
1. A method for measuring an analyte in a fluid sample in a meter system, comprising:
-
initiating a measuring period for a fluid sample;
measuring a property of the fluid sample at each of n points in time, said points in time being spaced at predetermined intervals to form a sequence of n measurement values, where n is an integer;
comparing two nonconsecutive measurement values to determine at least one ratio;
terminating the measuring of the fluid sample when at least one of said at least one ratio meets predetermined criteria indicating a final analyte value can be accurately determined; and
determining a final analyte value based on said measurement values. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14)
-
-
15. A meter system for measuring an analyte in a fluid sample, comprising:
-
a light intensity control circuit for measuring reflectance values of an analytic test strip onto which a fluid sample has been applied; and
a processor for (a) initiating a measuring period for the fluid sample;
(b) measuring the reflectance of a portion of the test strip onto which the fluid sample has been applied at each of n points in time, said points in time being spaced at predetermined intervals to form a sequence of n calculated measurement values, where n is an integer;
(c) comparing two nonconsecutive measurement values to determine at least one ratio, (d) terminating the reflectance measuring when at least one of said at least one ratio meets predetermined criteria indicating a final analyte value can be accurately determined; and
(e) determining a final analyte value based on said measurement values; and
a display for reporting said final analyte value in a user comprehensible format.- View Dependent Claims (16, 17, 18, 19, 20, 21, 22, 23, 24, 25)
-
-
26. A method for measuring the concentration of glucose in a biological fluid sample in a meter system, comprising:
-
initiating a measuring period for a biological fluid sample;
measuring a property of the fluid sample at each of n points in time, said points in time being spaced at predetermined intervals to form a sequence of n measurement values, where n is an integer and greater than 2;
comparing two nonconsecutive measurement values to determine at least one ratio;
terminating the measuring of the biological fluid sample when at least one of said at least one ratio meets predetermined criteria indicating a final glucose concentration value can be accurately determined; and
determining a final glucose concentration value based on said measurement values. - View Dependent Claims (27, 28, 29, 30, 31, 32, 33, 34, 35, 36)
-
Specification