Rapid prototyping and manufacturing process
First Claim
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1. A method of rapidly fabricating prototypes of multiple medical devices, each having individually selected parameters, using a computer-guided system, comprising:
- selecting the parameters of each of the devices to be fabricated;
designing prototypes of the devices using a statistically-based multifactorial computer-guided system design to vary composition and structure of the medical devices according to the parameters; and
manufacturing the medical devices in accordance with the selected parameters within a single manufacturing run.
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Abstract
A fabrication method to rapidly fabricate different prototypes of drug delivery systems, medical devices, pharmaceutical dosage forms, tissue scaffolds or other bioaffecting agents in small batches or individual forms using a computer-guided system to vary the composition and structure in order to optimize the product and the manufacturing process. The process is immediately scalable. An Expert System can be used with the method to recommend different compositions and designs of the prototypes, devices, dosage forms, tissue scaffold or other bioaffecting agents.
125 Citations
22 Claims
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1. A method of rapidly fabricating prototypes of multiple medical devices, each having individually selected parameters, using a computer-guided system, comprising:
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selecting the parameters of each of the devices to be fabricated;
designing prototypes of the devices using a statistically-based multifactorial computer-guided system design to vary composition and structure of the medical devices according to the parameters; and
manufacturing the medical devices in accordance with the selected parameters within a single manufacturing run. - View Dependent Claims (2)
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3. A method of rapid prototyping and manufacturing of multiple pharmaceutical dosage forms, each having individually selected parameters, comprising:
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selecting the parameters of the pharmaceutical dosage forms to be fabricated;
designing prototypes of the selected pharmaceutical dosage forms using a computer-guided manufacturing process; and
manufacturing the pharmaceutical dosage forms in accordance with the selected designs of the prototype within a single manufacturing run. - View Dependent Claims (4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19)
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20. A method of rapid formulation development of multiple tissue scaffolds using a computer-guided manufacturing process, comprising:
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selecting physio-chemical parameters and physio-mechanical properties of the tissue scaffolds, producing prototypes of the tissue scaffolds based on the physio-chemical parameters;
testing the physio-mechanical properties of the prototype; and
reproducing multiple prototypes for stability testing in a single manufacturing run. - View Dependent Claims (21, 22)
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Specification