Neuropharmacological treatments of sleep-related breathing disorders
First Claim
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1. A method of preventing or ameliorating sleep-related breathing disorder the method comprising administering to a patient in need thereof an effective amount of a glutamate receptor antagonist wherein the effects of the antagonist are exerted only in the central nervous system.
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Abstract
The present invention relates generally to pharmacological methods for the prevention or amelioration of sleep-related breathing disorders via administration of agents or combinations of agents that possess glutamate-related and/or glycine-related pharmacological activity or that modulate the release of either glutamate or glycine (or both) from nerve terminals with the central nervous system.
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6 Claims
- 1. A method of preventing or ameliorating sleep-related breathing disorder the method comprising administering to a patient in need thereof an effective amount of a glutamate receptor antagonist wherein the effects of the antagonist are exerted only in the central nervous system.
- 4. A method of preventing or ameliorating sleep-related breathing disorders the method comprising administering to a patient in need thereof an effective amount of an agent or combination of agents that inhibit the release of glutamate from nerve terminals within the central nervous system.
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