Dialysis machine, in particular for home use

• US 6,558,340 B1
• Filed: 12/15/2000
• Issued: 05/06/2003
• Est. Priority Date: 06/17/1998
• Status: Expired due to Term

• Current Assignee: Physidia SAS
• Original Assignee: Valemont Participation Corp.
• Inventors: Traeger, Jules
• Primary Examiner(s): Lazarus, Ira S.
• Assistant Examiner(s): NGUYEN, CAMTU TRAN
• Application Number:
  US09/719,790
• Time in Patent Office: 872 Days
• Field of Search: 604/5.01, 604/4.01, 604/6.01, 604/6.06, 604/6.09, 604/29, 604/30, 210/646, 210/645, 210/651, 210/636
• US Class Current: 604/5.01
• CPC Class Codes: A61M 1/16 with membranes
• CPC Class Codes: A61M 1/1605 Physical characteristics of the dialysate fluid
• CPC Class Codes: A61M 2205/3331 Pressure; Flow
• CPC Class Codes: A61M 2205/3393 by weighing the reservoir
• CPC Class Codes: A61M 2205/50 with microprocessors or computers
• CPC Class Codes: A61M 5/1486 the bags being substantially completely surrounded by fluid

Abstract

The invention concerns a dialysis machine (10) comprising a dialyzer (20) having a first inlet (21) and a first outlet (22) for the bloodstream, dialysate supply mechanism (25), an arterial line (16) connected between the patent'"'"'s arteriovenous fistula and the dialyzer, a venous line (17) connected between the arteriovenous fistula and the dialyzer, a pump (28) coupled with the arterial line, a dialysate supply line (31), connected between the dialysate supply mechanism and the dialyzer, a dialysate evacuation line (33) connected between a dialysate recuperating container (27) and the dialyzer. The sterile dialysate bags are arranged in a chamber (26) under a gas pressure.

Claims

1. A dialysis machine comprising a dialyzer with a first blood circulation inlet and a first blood circulation outlet, a dialysate supply means, an arterial line connected between an arteriovenous fistula in a patient and the first dialyzer inlet, a venous line connected between the arteriovenous fistula and the first dializyer outlet, a pump coupled with the arterial line, a dialysate inlet line connected between the dialysate supply means and a second dialyzer inlet, and a dialysate evacuation line connected between a dialysate collection container and a second dialyzer outlet, wherein the dialysate supply means (25) includes at least two chambers (26), each of the at least two chambers containing at least one primary pouch (25a) of sterile dialysate, each of the at least one primary-pouches (25a) connected to the dialysate inlet line (31) leading to the dialyzer (20), pressurizing means for separately pressurizing each of the at least one primary pouches (25a) to provoke the flow of dialysate into the inlet line (31), each of the at least two chambers further containing at least one reserve pouch (25b) of sterile dialysate, with each of the at least one reserve pouches (25b) connected by a conduit (38) to a primary pouch (25a) within each of the at least two chambers (26), the dialysate inlet line (31) including a flow restrictor for generating a predetermined decrease in charge calculated so that for a given pressure in each of the at least two chambers (26), the flow rate and the pressure of the dialysate at the second inlet (23) on the dialyzer (20) have a constant given value, the dialysis machine including a volumetric device (36) connected to the evacuation line (33) at the second outlet (24) of the dialyzer (29), the volumetric device (36) designed to generate, in combination with the means for pressurizing the at least one primary pouch (25a) within each of the at least two chambers (26), a predetermined trans-membrane pressure in the dialyzer.

2. The dialysis machine according to claim 1, further comprising means for alternately clamping the conduits (38).

3. The dialysis machine according to claim 1, further comprising a frame (11) with a housing (12) containing the dialyzer (20), a folding cover (13) attached to the frame (11), the arterial line (16) located so it can be connected between an artery of the patient (19) and the first inlet (21 of the dialyzer (20), the venous line (17) located so it can be connected between a vein of the patient (19) and the first outlet (22) of the dialyzer (20), and the pressurizing means housed within said chamber (26).

4. The dialysis machine according to claim 1, wherein the housing (12) encloses the at least two chambers (26), and further includes a support integral with the frame (11) which holds the reserve pouches (25b).

5. The dialysis machine according to claim 4, wherein the support for the reserve pouches (25b) includes the cover (13).

7. The dialysis machine according to claim 5, further comprising at least one reserve pouch (25b) of sterile dialysate located outside each of the at least two chambers (26), each of the at least-one reserve pouches (25b) connected to one of the pouches (25a) by a conduit (38).

10. The dialysis machine according to claim 7, further comprising means for alternately clamping the conduits (38).

16. The dialysis machine according to claim 10, wherein the volumetric device (36) is a dialysate pump with an adjustable rate of flow.

19. The dialysis machine according to claim 7, further comprising a support integral with the frame (11), which holds the reserve pouches (25b) of sterile dialysate.

6. A dialysis machine comprising a dialyzer with a first blood circulation inlet and a first blood circulation outlet, a dialysate supply means, an arterial line connected between an arteriovenous fistula in a patient and the first dialyzer inlet, a venous line connected between the arteriovenous fistula and the first dialyzer outlet, a pump coupled with the arterial line, a dialysate inlet line connected between the dialysate supply means and a second dialyzer inlet, and a dialysate evacuation line connected between a dialysate collection container and a second dialyzer outlet, the dialysate supply means including sterile dialysate contained in at least one pouch (25a), each at least one pouch connected by the dialysate inlet line (31) to the dialyzer (20), and means for pressurizing the pouch (25a) to provoke the flow of dialysate into the inlet line (31), wherein the supply means includes at least two chambers each containing at least one pouch of sterile dialysate, each of said pouches capable of separate pressurization.

8. The dialysis machine according to claim 6, wherein the dialysate inlet line (31) has a flow restrictor for generating a predetermined decrease in charge calculated so that for a given pressure in the chamber (26) the flow rate and the pressure of the dialysate at said second inlet (23) on the dialyzer (20) have a constant value.

9. The dialysis machine according to claim 6, further comprising a volumetric device (36) connected to the evacuation line (33) at the second outlet (24) of the dialyzer (20), the volumetric device (36) capable of generating, in combination with the pressurizing means, a predetermined trans-membrane pressure in the dialyzer.

11. The dialysis machine according to claim 6, wherein the dialysate inlet line (31) leading to the dialyzer (20) is calibrated so that for a predetermined pressure in the chamber (26) the dialysate will flow at a rate ranging from about 100 to about 500 ml/minute.

12. The dialysis machine according to claim 11, wherein the dialysate inlet line (31) leading to the dialyzer (20) is calibrated so that for a predetermined pressure in the chamber (26) the dialysate will flow at a rate ranging from about 100 to about 250 ml/minute.

13. The dialysis machine according to claim 6, wherein the dialysate inlet line (31) consists at least partially of a reinforced calibrated tube of constant cross-section for a predetermined length.

14. The dialysis machine according to claim 6, wherein the pressurization means maintains an interior pressure within the chamber (26) that is sufficient to provoke the flow of dialysate through the inlet lines (30, 31), respectively, to a bubble trap (29) and to the dialyzer (20).

15. The dialysis machine according to claim 6, wherein the dialysate inlet lines (30, 31) are calibrated so that for a predetermined pressure in the chamber (26) flow rates within the inlet lines (30, 31) will have a constant given value.

17. The dialysis machine according to claim 6, further comprising a frame (11) with a housing (12) containing the dialyzer (20), a folding cover (13) attached to the frame (11), the arterial line (16) located such that it can be connected between an artery of a patient (19) and the first inlet (21) of the dialyzer (20), the venous line (17) located so it can be connected between a vein of the patient (19) and the first outlet (22) of the dialyzer (20), and the pressurizing means is housed within the chamber (26).

18. The dialysis machine according to claim 17, wherein the housing (12) encloses each of the at least two chambers (26).