Cell for electrochemical anaylsis of a sample

• US 6,562,210 B1
• Filed: 12/30/1999
• Issued: 05/13/2003
• Est. Priority Date: 12/30/1999
• Status: Expired due to Fees

• Current Assignee: Roche Diabetes Care Inc. (Roche Holding AG)
• Original Assignee: Roche Diagnostics Corporation (Roche Holding AG)
• Inventors: Bhullar, Raghbir Singh, Hill, Brian, Walling, Douglas P.
• Primary Examiner(s): Warden, Sr., Robert J.
• Assistant Examiner(s): Olsen, Kaj K.
• Application Number:
  US09/475,904
• Time in Patent Office: 1,230 Days
• Field of Search: 204/403.02, 204/403.03, 204/403.04, 204/403.1, 204/403.11, 204/403.12, 204/409
• US Class Current: 204/403.03
• CPC Class Codes: C12Q 1/001 Enzyme electrodes

Abstract

According to an aspect of the invention, an electrochemical cell for analysis of a sample is provided, comprising a dual electrode having a dielectric strip with electrical conductors on opposite sides. According to a preferred embodiment, the electrochemical cell comprises a base, and a first reagent the proximate the dual electrode. According to a further preferred embodiment, a second reagent is provided proximate the dual electrode. A cover may also be provided comprising a sample aperture. According to a particularly preferred embodiment, the first and second reagents are superposed, and the dual electrode is between the first and second reagents. The dual electrode separates the two and preserves chemical stability until a sample is applied.

Claims

1. A cell for electrochemical analysis of a liquid sample, comprising:

a base;

a spacer overlaying said base;

a dielectric strip overlaying said base and said spacer, said dielectric strip having opposing first and second surfaces;

a first electrical conductor on said first surface that defines a first sensing region;

a second electrical conductor on said second surface that defines a second sensing region opposite said first sensing region; and

a cover overlaying said dielectric strip, said spacer and said cover having respective apertures, said apertures aligned to define a well for receiving said liquid sample.

2. The cell of claim 1 further comprising a plurality of said cells connected in seriatim.

3. The cell of claim 1 further comprising a first reagent proximate said first and second sensing regions.

4. The cell of claim 3 further comprising a second reagent proximate said first and second sensing regions.

5. The cell of claim 1 further comprising:

a first reagent proximate said first sensing region; and

a second reagent proximate said second sensing region;

wherein said dielectric strip, said first electrical conductor, and said second electrical conductor are disposed between said first and second reagents.

6. The cell of claim 1 wherein said base comprises an aperture for an electrical connector and said cover comprises an aperture for an electrical connector, said first and second electrical conductors being accessible through said apertures.

7. The cell of claim 6 wherein said apertures are superposed.

8. A cell for electrochemical analysis of a liquid sample, comprising:

a base;

a spacer overlaying said base;

a dielectric strip overlaying said base and said spacer, said dielectric strip having opposing first and second surfaces;

a first electrical conductor on said first surface;

a second electrical conductor on said second surface;

wherein said first electrical conductor does not extend beyond said first surface, and said second electrical conductor does not extend beyond said second surface; and

a cover overlaying said dielectric strip, said spacer and said cover having respective side apertures, said side apertures being vertically aligned so that said liquid sample is drawn into said cell through said apertures.

9. The cell of claim 8 further comprising a plurality of said cells connected in seriatim.

10. The cell of claim 8 wherein said cell comprises a first reagent proximate said first electrical conductor.

11. The cell of claim 10 wherein said cell comprises a second reagent proximate said second electrical conductor.

12. The cell of claim 8 further comprising:

a first reagent proximate said first sensing region; and

a second reagent proximate said second sensing region;

wherein said dielectric strip, said first electrical conductor, and said second electrical conductor are disposed between said first and second reagents.

13. The cell of claim 8 further comprising a spacer on said base, said dielectric strip being on said spacer.

14. The cell of claim 8 further comprising a spacer on said base, said spacer having an aperture over said first and second electrical conductors, said cover having an aperture over said aperture in said spacer, both said apertures being over said gap.