×

Integrated monolithic microfabricated electrospray and liquid chromatography system and method

  • US 6,563,111 B1
  • Filed: 10/31/2000
  • Issued: 05/13/2003
  • Est. Priority Date: 09/17/1998
  • Status: Expired due to Term
First Claim
Patent Images

1. A method for generating an electrospray of a fluid, comprising:

  • providing a monolithic electrospray substrate having an injection side on an opposite planar side from an ejection surface, the monolithic substrate defining;

    an entrance orifice on the injection side, a nozzle on the ejection surface, a channel extending continuously through the monolithic substrate communicating with the entrance orifice and the nozzle, and a region surrounding the nozzle recessed from the ejection surface;

    introducing a fluid into the channel through the entrance orifice;

    providing a first electrode in electrical contact with the fluid;

    applying a first potential voltage to the fluid;

    positioning the nozzle adjacent to an extracting electrode; and

    ejecting the fluid in the form of an electrospray from the channel through the nozzle by applying or holding the extracting electrode at a second potential voltage different from the first potential voltage.

View all claims
  • 11 Assignments
Timeline View
Assignment View
    ×
    ×