Microtome having a motorized feed drive system

• US 6,568,307 B1
• Filed: 03/13/2000
• Issued: 05/27/2003
• Est. Priority Date: 03/12/1999
• Status: Expired due to Term

• Current Assignee: Leica Biosystems Nussloch GmbH (Danaher Corporation)
• Original Assignee: Leica Microsystems Nussloch GmbH (Danaher Corporation)
• Inventors: Günther, Bernd, Holtermüller, Siegbert, Metzner, Rolf, Walter, Roland, Scheck, Peter, Laudat, Andreas
• Primary Examiner(s): Peterson, Kenneth E.
• Application Number:
  US09/524,542
• Time in Patent Office: 1,170 Days
• Field of Search: 839/155, 83/36, 837/33, 833/67, 834/21
• US Class Current: 83/367
• CPC Class Codes: G01N 1/06 providing a thin slice, e.g. microtome
• CPC Class Codes: G01N 2001/066 electric
• CPC Class Codes: Y10T 83/536 Movement of work controlled
• CPC Class Codes: Y10T 83/6577 With means to adjust additional means

Abstract

A microtome (1) having a motorized feed drive system (2) for generating a relative movement between an object (7) that is to be cut and a cutting knife (4). A control circuit (8) and a pressure-sensitive sensor (9) are provided for detecting a position between the cutting knife (4) and the object (7). The motorized feed drive system (2) is switched via the control circuit (8) when the sensor (9) responds. The sensor (9) is equipped with a sensor surface (14) that is at least exactly as large as the surface (16) of the object (7). The sensor surface (14) is arranged parallel to the cutting plane (17).

Claims

1. A microtome, comprising:

a cutting knife and an object holder that are movable in a first direction relative to one another, wherein the cutting knife defines a cutting plane;

a motorized feed drive system for generating a relative movement in the first direction between the cutting knife and the object holder, wherein the object holder is adapted for holding an object which is to be cut and which has a frontal surface facing in the first direction; and

a cutting drive system for generating relative movement between the object holder and the cutting knife in the cutting plane, the feed drive system including a control circuit and a pressure-sensitive sensor for determining a relative position between the cutting knife and the object, wherein the sensor comprises a generally planar sensor surface that is at least as large as the frontal surface of the object, and the sensor surface is fixed in the first direction with respect to the cutting plane and is in an orientation that is parallel to the cutting plane, wherein the feed drive system and the cutting drive system are configured to selectively pre-position the object in front of said sensor and to provide relative movement between the object holder and said sensor until a leading edge of said object contacts said sensor, whereby said sensor generates a signal to said control circuit for determining said relative position, and wherein for final positioning of the object in preparation for cutting the object the motorized feed drive system is activated by the control circuit in response to said relative position determined based upon said signal from the sensor.

2. A microtome as defined in claim 1, wherein the pressure-sensitive sensor comprises a sensor that generates a signal in response to initial contact between the sensor surface and any surface of the object.

3. A microtome as defined in claim 1, further comprising a motorized device, operatively connected to the control circuit, for orienting the object holder relative to the cutting plane in response to signals received from the sensor.

4. A microtome as defined in claim 3, wherein the motorized device comprises two motors for orienting the object holder in two dimensions relative to the cutting plane.

5. A microtome as defined in claim 4, wherein the motorized device comprises a control system for automatically orienting the object holder in an orientation that aligns the frontal surface of the object with the cutting plane.

6. A microtome as defined in claim 5, wherein the control system includes an operating program that multiply orients the object holder, that for each orientation moves the object holder in the first direction by way of the motorized feed drive system until first contact is made between the object and the sensor and that measures the respective distances moved in each instance, and that selects an orientation based on said measured distances.

7. A microtome as defined in claim 5, wherein the sensor comprises a position-sensitive sensor that determines the position on the sensor surface at which contact with the object is first made, and the control system includes an operating program that multiply orients the object holder, that for each orientation moves the object holder in the first direction by way of the motorized feed drive system until first contact is made between the object and the sensor and that selects an orientation based on the positions of first contact determined.

8. A microtome as defined in claim 1, wherein the motorized feed drive system comprises a stepper motor electrically connected to the control circuit.

9. A microtome as defined in claim 1, wherein the motorized feed drive system comprises a DC motor and an encoder, and the DC motor and the encoder are electrically connected to the control circuit.

10. A microtome as defined in claim 1, wherein the control circuit includes a memory for saving a position of the feed drive system when the sensor responds.

11. A microtome as defined in claim 1, wherein the sensor comprises a piezosensor or film touchpad.

12. A microtome as defined in claim 1, wherein the sensor comprises a position-sensitive surface sensor that determines the position on the sensor surface at which contact with the object is first made.

13. A microtome as defined in claim 12, wherein the position-sensitive surface sensor comprises a two-dimensional potentiometer pad.

14. A microtome as defined in claim 1, wherein the control circuit is connected to a control panel that permits manual input of modifiable parameters for controlling the feed drive system.

15. A microtome as defined in claim 1, wherein the control circuit includes a system for adjusting the standard thickness of the objects that are to be cut.

16. A microtome as defined in claim 1, wherein the microtome comprises a disk microtome, and the object that is to be cut is arranged on a rotatably mounted component of the disk microtome.

17. A microtome as defined in claim 1, wherein the sensor is positioned in a plane that is displaced from said cutting plane in the direction of the cutting knife.

18. A microtome that is capable of automatically aligning the frontal surface of an object to be cut with the cutting plane of the microtome, comprising:

a cutting knife and an object holder that are movable in a first direction relative to one another, wherein the cutting knife defines a cutting plane;

a motorized feed drive system for generating a relative movement in the first direction between the cutting knife and the object holder for holding an object, wherein the object holder is adapted for holding an object which is to be cut and which has a frontal surface facing in the first direction;

a cutting drive system for generating relative movement between the object holder and the cutting knife in the cutting plane, the feed drive system including a control circuit and a pressure-sensitive sensor for determining a relative position between the cutting knife and the object, wherein the sensor comprises a generally planar sensor surface that is at least as large as the frontal surface of the object, and the sensor surface is fixed in the first direction with respect to the cutting plane and is in an orientation that is parallel to the cutting plane, wherein the feed drive system and the cutting drive system are configured to selectively pre-position the object in front of said sensor and to provide relative movement between the object holder and said sensor until a leading edge of said object contacts said sensor, whereby said sensor generates a signal to said control circuit; and

a motorized device, operatively connected to the control circuit, for adjusting an orientation angle of the object holder relative to the cutting plane in response to signals received from the sensor to automatically align the frontal surface of an object to be cut with the cutting plane of the microtome.

19. A microtome as defined in claim 18, wherein the motorized device comprises two motors for orienting the object holder in two dimensions relative to the cutting plane.

20. A microtome as defined in claim 19, wherein the motorized device comprises a control system for automatically orienting the object holder in an orientation that aligns the frontal surface of the object with the cutting plane.

21. A microtome as defined in claim 20, wherein the control system includes an operating program that multiply orients the object holder, that for each orientation moves the object holder in the first direction by way of the motorized feed drive system until first contact is made between the object and the sensor and that measures the respective distances moved in each instance, and that selects an orientation based on said measured distances.

22. A microtome as defined in claim 20, wherein the sensor comprises a position-sensitive sensor that determines the position on the sensor surface at which contact with the object is first made, and the control system includes an operating program that multiply orients the object holder, that for each orientation moves the object holder in the first direction by way of the motorized feed drive system until first contact is made between the object and the sensor and that selects an orientation based on the positions of first contact determined.