Guidewires having a vapor deposited primer coat

• US 6,569,107 B2
• Filed: 01/29/2001
• Issued: 05/27/2003
• Est. Priority Date: 06/05/1998
• Status: Expired due to Term

• Current Assignee: Advanced Cardiovascular Systems Incorporated (Abbott Laboratories)
• Original Assignee: Advanced Cardiovascular Systems Incorporated (Abbott Laboratories)
• Inventors: Jalisi, Marc Mehrzad, Biagtan, Emmanuel C.
• Primary Examiner(s): Hindenburg, Max F.
• Assistant Examiner(s): WINGOOD, PAMELA LYNN
• Application Number:
  US09/772,803
• Publication Number:
  US 20010003146A1
• Time in Patent Office: 848 Days
• Field of Search: 600/433, 600/434, 600/435, 604/523-533, 623/1--
• US Class Current: 600/585
• CPC Class Codes: A61L 2420/08 Coatings comprising two or more layers
• CPC Class Codes: A61L 29/085 Macromolecular materials
• CPC Class Codes: A61L 29/103 Carbon
• CPC Class Codes: A61L 31/082 Inorganic materials
• CPC Class Codes: A61L 31/10 Macromolecular materials
• CPC Class Codes: A61M 25/0045 multi-layered, e.g. coated coating materials A61L29/08
• CPC Class Codes: A61M 25/09 Guide wires
• CPC Class Codes: A61M 25/09016 with mandrils
• CPC Class Codes: Y10T 428/2942 Plural coatings

Abstract

An intraluminal device having an adhesive primer coat formed of a carbonaceous material and a lubricious top coat of a hydrophilic polymeric material. The invention also comprises the methods of making such intraluminal devices. The primer coat of the invention may comprise pure carbon, or a carbon based material such as a polymer. Preferably, the primer coat has a thickness of about 0.1 to about 2 μm. In a presently preferred embodiment, the primer coat is applied using chemical vapor deposition (CVD), but in certain embodiments, physical vapor deposition (PVD) may be suitable. The deposited primer coat forms an effective substrate for adhesion of the hydrophilic polymer top coat.

Claims

1. An intraluminal stent having a primer coat formed of a carbonaceous material and vapor deposited on at least a portion of the device, and a hydrophilic polymer top coat on at least a portion of the primer coat.

2. The intraluminal stent of claim 1, wherein the primer coat has a uniform thickness of not more than about 2 μ

m.

3. The intraluminal stent of claim 1, wherein the primer coat is selected from the group consisting of carbon, plasma polymerized nylon, plasma polymerized polyurethane, plasma polymerized polyethylene, and plasma polymerized hydrocarbons.

4. The intraluminal stent of claim 1, wherein the top coat is selected from the group consisting of poly(N-vinylpyrrolidone), and polyethylene oxide.

5. The intraluminal stent of claim 1, wherein the top coat has a thickness of about 0.0025 mm to about 0.015 mm.