Pressure-controlled continuous coronary sinus occlusion device and methods of use

• US 6,569,145 B1
• Filed: 03/25/1999
• Issued: 05/27/2003
• Est. Priority Date: 03/25/1999
• Status: Expired due to Term

• Current Assignee: Bayer Schering Pharma AG (Bayer AG)
• Original Assignee: TransVascular, Inc. (Medtronic Plc)
• Inventors: Wilcox, Robert L., Bley, Robert S., Shmulewitz, Ascher
• Primary Examiner(s): Kennedy, Sharon
• Assistant Examiner(s): WILLIAMS, CATHERINE SERKE
• Application Number:
  US09/275,797
• Time in Patent Office: 1,524 Days
• Field of Search: 604/500, 604/506, 604/507, 604/508, 604/509, 604/523, 604/6.16, 604/8, 604/9, 604/93.01, 604/96.01, 604/99.04, 604/102.01, 604/102.02, 604/102.03, 604/104, 604/264, 604/907, 604/912, 604/914, 604/915-21
• US Class Current: 604/509
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12109 in a blood vessel
• CPC Class Codes: A61B 17/12131 characterised by the type of occluding device
• CPC Class Codes: A61B 17/12136 Balloons
• CPC Class Codes: A61B 17/1219 expandable in contact with liquids
• CPC Class Codes: A61M 2025/0076 Unidirectional valves
• CPC Class Codes: A61M 2025/1052 for temporarily occluding a vessel for isolating a sector
• CPC Class Codes: A61M 2210/125 Heart
• CPC Class Codes: A61M 25/0075 Valve means

Abstract

Apparatus and methods for perfusing ischemic myocardium are provided using a tubular member having an end region adapted to be disposed in a portion of a patient'"'"'s venous vasculature. The end region includes a lumen and a valve in communication with the lumen that controls pressure within an occluded portion of the vasculature by venting excess blood at a location proximal of a point of occlusion of the vasculature via the valve. An occlusion element optionally may be provided in the end region that retains the tubular member within the patient'"'"'s venous vasculature and occludes the flow of blow around the lumen.

Claims

1. A method of providing retrograde transvenous myocardial perfusion, the comprising:

providing a device comprising a tubular member having a distal portion adapted to be disposed in a patient'"'"'s venous system, a proximal end having means for sealing the proximal end, a first valve which opens when pressure distal to the first valve exceeds a predetermined maximum pressure and an occlusion element located on said distal portion;

delivering the device into a portion of a patient'"'"'s venous vasculature;

using the occlusion element to substantially block blood flow at a selected location within the patient'"'"'s venous vasculature; and

opening the first valve when the venous blood pressure distal to the valve exceeds the predetermined maximum pressure, thereby allowing blood to flow through the first valve in the direction of normal venous blood flow so long as the pressure distal to the first valve is in excess of the predetermined maximum pressure.

2. The method of claim 1 wherein the device further comprises an expandable member in communication with the lumen, the method further comprising contracting the expandable member to perfuse the portion of the patient'"'"'s venous system during cardiac diastole.

3. The method of claim 1 wherein the means for sealing further comprises a hemostatic valve communicating with the lumen, the method further comprising injecting a therapeutic substance through the hemostatic valve and into the patient'"'"'s venous system.

4. The method of claim 1 wherein the device further comprises one or more additional valves, and a sheath disposed relative to the one or more additional valves, the method further comprising:

moving the sheath relative to the one or more additional valves to adjust a value of a pressure related parameter.

5. The method of claim 4 wherein the tubular member comprises an elongated catheter, the method further comprising:

coupling the proximal end to a monitoring device to measure a pressure in the lumen; and

moving the sheath relative to the one or more additional valves to adjust the value of the pressure measured by the monitoring device.