Methods for emboli containment

• US 6,569,148 B2
• Filed: 01/25/2001
• Issued: 05/27/2003
• Est. Priority Date: 05/20/1996
• Status: Expired due to Fees

• Current Assignee: Medtronic Ave Incorporated (Medtronic Plc)
• Original Assignee: Medtronic Ave Incorporated (Medtronic Plc)
• Inventors: Azizi, Gholam RezaZadno, Muni, Ketan P., Bagaoisan, Celso J., Bleam, Jefferey C.
• Primary Examiner(s): Casler, Brian L.
• Assistant Examiner(s): MAYNARD, JENNIFER J
• Application Number:
  US09/769,775
• Publication Number:
  US 20020029031A1
• Time in Patent Office: 852 Days
• Field of Search: 606/1, 606/127, 606/167, 606/159, 606/180, 606/194, 604/22, 604/96-104, 604/500, 604/506, 604/507-510
• US Class Current: 604/509
• CPC Class Codes: A61B 17/22 Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for dilators A61M29/00
• CPC Class Codes: A61B 2017/22067 Blocking; Occlusion A61B2017/22054 takes precedence
• CPC Class Codes: A61B 2017/22084 stone- or thrombus-dissolving
• CPC Class Codes: A61B 2217/005 with suction drainage system
• CPC Class Codes: A61M 2025/0018 having a plug, e.g. an inflatable plug for closing catheter lumens
• CPC Class Codes: A61M 2025/0037 characterized by lumina being arranged side-by-side
• CPC Class Codes: A61M 2025/0081 Soft tip
• CPC Class Codes: A61M 2025/0183 Rapid exchange or monorail catheters
• CPC Class Codes: A61M 2025/09008 having a balloon
• CPC Class Codes: A61M 2025/09175 having specific characteristics at the distal tip
• CPC Class Codes: A61M 2025/1015 having two or more independently movable balloons where the distance between the balloons can be adjusted, e.g. two balloon catheters concentric to each other forming an adjustable multiple balloon catheter system
• CPC Class Codes: A61M 2025/1031 Surface processing of balloon members, e.g. coating or deposition; Mounting additional parts onto the balloon member's surface
• CPC Class Codes: A61M 2025/1052 for temporarily occluding a vessel for isolating a sector
• CPC Class Codes: A61M 2025/1079 having radio-opaque markers in the region of the balloon
• CPC Class Codes: A61M 2025/109 having balloons for removing solid matters, e.g. by grasping or scraping plaque, thrombus or other matters that obstruct the flow
• CPC Class Codes: A61M 2025/1093 having particular tip characteristics
• CPC Class Codes: A61M 25/0009 Making of catheters or other medical or surgical tubes
• CPC Class Codes: A61M 25/0026 Multi-lumen catheters with stationary elements catheter assemblies comprising a catheter in combination with a guide tube, sheath or sleeve A61M2025/0681; catheters comprising telescoping coaxial elements A61M2025/0175
• CPC Class Codes: A61M 25/0029 characterized by features relating to least one lumen located at the middle part of the catheter, e.g. slots, flaps, valves, cuffs, apertures, notches, grooves or rapid exchange ports catheter shaft surface irregularities A61M2025/006
• CPC Class Codes: A61M 25/005 with embedded materials for reinforcement, e.g. wires, coils, braids
• CPC Class Codes: A61M 25/0053 : having a variable stiffness along the longitudinal axis, e.g. by varying the pitch of the coil or braid
• CPC Class Codes: A61M 25/0054 : with regions for increasing flexibility
• CPC Class Codes: A61M 25/0068 : Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
• CPC Class Codes: A61M 25/007 : Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
• CPC Class Codes: A61M 25/0075 : Valve means
• CPC Class Codes: A61M 25/008 : Strength or flexibility characteristics of the catheter tip
• CPC Class Codes: A61M 25/09 : Guide wires
• CPC Class Codes: A61M 25/09033 : with fixed mandrils, e.g. mandrils fixed to tip; Tensionable wires
• CPC Class Codes: A61M 25/10 : Balloon catheters A61M25/0125 takes precedence; embolectomy A61B17/22032; retractors A61B17/02; inflatable balloons for placing stents or stent-grafts A61F2/958 ; stomach balloons for treatment of obesity A61F5/0003; oesophagal tubes A61J15/00
• CPC Class Codes: A61M 25/1011 : Multiple balloon catheters
• CPC Class Codes: A61M 25/1018 : Balloon inflating or inflation-control devices
• CPC Class Codes: A61M 25/10184 : Means for controlling or monitoring inflation or deflation
• CPC Class Codes: A61M 25/1027 : Making of balloon catheters
• CPC Class Codes: A61M 25/104 : used for angioplasty
• CPC Class Codes: B29C 55/04 : uniaxial, e.g. oblique

Abstract

A multi-catheter emboli containment system is disclosed which is adapted to provide at least one pair of optimized paths for irrigation and aspiration fluid flow. Through careful design of the cross-sectional area of these paths, the present system is able to be compactly utilized in even the smaller size blood vessels. The catheter system itself is provided with occlusive devices to form an emboli containment chamber in which irrigation and aspiration occur. The catheter system of the present invention provides an improved emboli containment and removal system which can be utilized in a wide range of vessel diameters. The system is easy to use and can quickly and efficiently evacuate the containment chamber.

Claims

1. A method of treating a blood vessel, the method comprising:

delivering a first catheter having a lumen in fluid communication with a distal opening in the first catheter into the blood vessel;

delivering a guidewire through the lumen of the first catheter into the blood vessel, the guidewire having a proximal end and a distal end and an occlusive device disposed along the distal end, the occlusive device being actuatable between a nonexpanded state and an expanded state;

delivering a therapy catheter over the guidewire and through the lumen of the first catheter until a distal end of the therapy catheter is proximal to the occlusive device and near a treatment site;

actuating the occlusive device into the expanded state within the vessel at a location distal to a treatment site;

performing therapy on the treatment site using the therapy catheter;

withdrawing the therapy catheter from the blood vessel;

delivering an irrigation catheter over the guidewire until a distal end of the irrigation catheter is proximal to the occlusive device and distal to the distal opening of the first catheter;

supplying irrigation fluid through the irrigation catheter into the blood vessel; and

drawing blood and irrigation fluid from the blood vessel into the distal opening of the first catheter while the blood vessel is occluded only by the occlusive device, whereby particles in the blood vessel proximal to the occlusive device are carried by the blood and the irrigation fluid from the vessel into the distal opening and through the lumen of the first catheter.

2. The method of claim 1, wherein the first catheter is a guide catheter.

3. The method of claim 1, wherein the therapy catheter is delivered after actuation of the occlusive device.

4. The method of claim 1, wherein the therapy catheter is delivered before actuation of the occlusive device.

5. The method of claim 1, wherein the therapy catheter is a balloon catheter.

6. The method of claim 1, wherein the therapy catheter deploys a stent.

7. The method of claim 1, wherein the guidewire is hollow.

8. The method of claim 1, wherein the occlusive device is an inflatable balloon.

9. The method of claim 1, wherein the irrigation catheter includes a side member attached along a distal end of the irrigation catheter, the side member defining a side lumen adapted for slidably receiving the guidewire to enable delivery of the irrigation catheter over the guidewire.

10. The method of claim 9, wherein the side member is between about 5 cm and 30 cm in length.

11. The method of claim 9, wherein the side member includes a side wall formed with a longitudinal slit for enabling the guidewire to be inserted into the side lumen through the side wall.

12. The method of claim 1, wherein the irrigation catheter is delivered over the guidewire until the distal end of the irrigation catheter is distal to the treatment site, whereby irrigation fluid flows from the distal end of the irrigation catheter across the treatment site to the distal opening in the first catheter.