Bioactive three loop coil

• US 6,569,179 B2
• Filed: 08/16/2001
• Issued: 05/27/2003
• Est. Priority Date: 11/10/1998
• Status: Expired due to Term

• Current Assignee: Stryker European Operations Holdings, LLC (Stryker Corporation)
• Original Assignee: Scimed Life Systems Incorporated (Boston Scientific Corporation)
• Inventors: Ho, Hanh, Teoh, Clifford, Quan, Kenneth W. Jr.
• Primary Examiner(s): Jackson, Gary
• Application Number:
  US09/931,662
• Publication Number:
  US 20020004681A1
• Time in Patent Office: 649 Days
• Field of Search: 606/213, 606/191, 606/194, 606/198, 604/514
• US Class Current: 606/191
• CPC Class Codes: A61B 17/12022 Occluding by internal devices, e.g. balloons or releasable wires plugging an opening in the wall of an organ A61B17/0057; occluders for the cervical canal A61F6/146; vas deferens occluders A61F6/20
• CPC Class Codes: A61B 17/12113 within an aneurysm
• CPC Class Codes: A61B 17/12145 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/1215 comprising additional materials, e.g. thrombogenic, having filaments, having fibers, being coated
• CPC Class Codes: A61B 17/12172 having a pre-set deployed three-dimensional shape methods of manufacturing A61B2017/00526
• CPC Class Codes: A61B 17/12177 comprising additional materials, e.g. thrombogenic, having filaments, having fibers or being coated
• CPC Class Codes: A61B 2017/12063 electrolytically detachable
• CPC Class Codes: A61B 90/39 Markers, e.g. radio-opaque or breast lesions markers
• CPC Class Codes: A61F 2/0077 Special surfaces of prostheses, e.g. for improving ingrowth A61F2/30767 takes precedence
• CPC Class Codes: A61L 2430/36 for embolization or occlusion, e.g. vaso-occlusive compositions or devices artificial blood vessels A61L27/507
• CPC Class Codes: A61L 31/044 Collagen
• CPC Class Codes: A61L 31/06 obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds A61L31/041 takes precedence
• CPC Class Codes: A61L 31/10 Macromolecular materials
• CPC Class Codes: A61L 31/16 Biologically active materials, e.g. therapeutic substances A61L31/047 takes precedence
• CPC Class Codes: C08L 65/04 Polyxylenes
• CPC Class Codes: C08L 67/04 Polyesters derived from hydroxycarboxylic acids, e.g. lactones C08L67/06 takes precedence

Abstract

One aspect of the present invention pertains to an implantable medical device for at least partially obstructing a neck portion of a vascular aneurysm. The implantable medical device includes an occlusion subassembly having a central tubular member and at least one lateral protrusion fixedly attached to the central tubular member. The lateral protrusion(s) and the central tubular member are of a size and overall flexibility to lodge at the neck portion of the vascular aneurysm. A coil is attached to the lateral protrusion.

Claims

1. An implantable medical device for at least partially obstructing a neck portion of a vascular aneurysm, comprising:

an occlusion subassembly comprising a central member and at least one lateral protrusion fixedly attached to the central member, said at least one lateral protrusion and the central member being of a size and overall flexibility to lodge at the neck portion of the vascular aneurysm; and

a coil attached to the lateral protrusion.

2. The implantable medical device of claim 1, further comprising a therapeutic agent disposed on at least one portion of the coil.

3. The implantable medical device of claim 2, wherein the therapeutic agent comprises a biodegradable material.

4. The implantable medical device of claim 3, wherein the therapeutic agent takes the form of a tubular member that is coaxially disposed about at least one portion of the coil.

5. The implantable medical device of claim 1, further comprising a material for encouraging a cellular response disposed on at least one portion of the coil.

6. The implantable medical device of claim 5, wherein the material for encouraging said cellular response comprises a polymeric material.

7. The implantable medical device of claim 5, wherein the material for encouraging said cellular response further comprises at least one element in the form of a fiber.

8. The implantable medical device of claim 5, wherein the material for encouraging said cellular response is fibrogenic.

9. The implantable medical device of claim 5, wherein the material for encouraging said cellular response is biodegradable.

10. The implantable medical device of claim 9, wherein the material for encouraging said cellular response comprises polyglycolic acid.

11. The implantable medical device of claim 9, wherein the material for encouraging said cellular response comprises polylactic acid.

12. The implantable medical device of claim 9, wherein the material for encouraging said cellular response comprises a mixture of polyglycolic acid and polylactic acid.

13. The implantable medical device of claim 9, wherein the material for encouraging the cellular response comprises a copolymer of polyglycolic acid and polylactic acid.

14. The implantable medical device of claim 7, wherein said at least one element in the form of a fiber is a multiplicity of elements in the form of fibers.

15. The implantable medical device of claim 14, wherein the multiplicity of elements in the form of fibers comprise a biodegradable material.

16. The implantable medical device of claim 7, wherein said at least one element in the form of a fiber is a bundle of individual fiber strands.

17. The implantable medical device of claim 16, wherein the bundle of individual fiber strands comprises a biodegradable material.

18. The implantable medical device of claim 1, further comprising a fiberous woven tubular member extending coaxially about at least one portion of the coil.

19. The implantable medical device of claim 18, wherein the fiberous woven tubular member comprises a material for encouraging a cellular response and that is biodegradable.

20. The implantable medical device of claim 19, wherein the fiberous woven tubular member is braided.

21. An implantable medical device, comprising:

a loop of wire having first and second ends connected to a base member;

a coil radially disposed about a portion of the loop of wire; and

a material for encouraging a cellular response disposed on at least one portion of the coil, the material also being biodegradable.

22. The implantable medical device of claim 21, wherein the material takes the form of a tubular member disposed on at least one portion of the coil.

23. The implantable medical device of claim 21, wherein the material is sprayed on at least one portion of the coil.

24. The implantable medical device of claim 21, wherein the material is dip coated on at least one portion of the coil.

25. The implantable medical device of claim 21, further comprising a marker coil radially disposed about a portion of the loop of wire.

26. The implantable medical device of claim 21, wherein the material for encouraging said cellular response comprises polyglycolic acid.

27. The implantable medical device of claim 21, wherein the material for encouraging said cellular response comprises polylactic acid.

28. The implantable medical device of claim 21, wherein the material for encouraging said cellular response comprises a mixture of polyglycolic acid and polylactic acid.

29. The implantable medical device of claim 21, wherein the material for encouraging said cellular response comprises a copolymer of polyglycolic acid and polylactic acid.

30. An implantable medical device, comprising:

a loop of wire having first and second ends connected to a base member;

a coil radially disposed about a portion of the loop of wire; and

a fiberous woven tubular member coaxially engaging at least one portion of the coil.

31. The implantable medical device of claim 30, wherein the fiberous woven tubular member comprises a material for encouraging a cellular response and that is biodegradable.

32. The implantable medical device of claim 31, wherein the material for encouraging said cellular response comprises polyglycolic acid.

33. The implantable medical device of claim 30, wherein the material for encouraging said cellular response comprises polylactic acid.

34. The implantable medical device of claim 31, wherein the material for encouraging said cellular response comprises a mixture of polyglycolic and polylactic acid.

35. The implantable medical device of claim 31, wherein the material for encouraging said cellular response comprises a copolymer of polyglycolic and polylactic acid.