Bacterial strain, processes plant extracts, compositions containing same, processes for their preparation and their therapeutic and industrial applications

• US 6,569,424 B2
• Filed: 11/13/2001
• Issued: 05/27/2003
• Est. Priority Date: 06/03/1999
• Status: Expired due to Fees

• Current Assignee: Hitachi Printing Solutions, Ltd. (Ricoh Company Limited)
• Original Assignee: Bio Balance Corp.
• Inventors: Olshenitsky, Mark, Buchman, Genadi
• Primary Examiner(s): Tate, Christopher R.
• Assistant Examiner(s): Srivastava, Kailash C.
• Application Number:
  US09/986,861
• Publication Number:
  US 20020054868A1
• Time in Patent Office: 560 Days
• Field of Search: 424/725, 424/93.3, 424/736, 424/777, 424/778, 424/773, 424/774, 424/775, 424/776, 424/779, 426/531, 426/541, 426/542, 426/599, 426/615, 426/616, 426/623, 426/629, 426/630, 426/635, 426/648, 426/655
• US Class Current: 424/93.3
• CPC Class Codes: A23K 10/18 of live microorganisms
• CPC Class Codes: A23K 20/10 Organic substances
• CPC Class Codes: A23L 21/20 Products from apiculture, e.g. royal jelly or pollen; Substitutes therefor
• CPC Class Codes: A23L 27/84 Flavour masking or reducing agents
• CPC Class Codes: A23L 29/065 Microorganisms addition of bacteria for nutritional purposes A23L33/135
• CPC Class Codes: A23L 33/105 Plant extracts, their artificial duplicates or their derivatives
• CPC Class Codes: A61K 2300/00 Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
• CPC Class Codes: A61K 35/644 Beeswax; Propolis; Royal jelly; Honey
• CPC Class Codes: A61K 35/741 Probiotics probiotic yeast, e.g. saccharomyces A61K36/06
• CPC Class Codes: A61K 36/185 Magnoliopsida (dicotyledons)
• CPC Class Codes: A61K 36/23 Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
• CPC Class Codes: A61K 36/31 Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
• CPC Class Codes: A61K 36/48 Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
• CPC Class Codes: A61K 36/534 Mentha (mint)
• CPC Class Codes: A61K 36/752 Citrus, e.g. lime, orange or lemon
• CPC Class Codes: A61K 36/8962 Allium, e.g. garden onion, leek, garlic or chives
• CPC Class Codes: A61P 1/00 Drugs for disorders of the alimentary tract or the digestive system
• CPC Class Codes: A61P 1/04 for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
• CPC Class Codes: A61P 1/14 Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
• CPC Class Codes: A61P 31/04 Antibacterial agents
• CPC Class Codes: A61P 35/00 : Antineoplastic agents
• CPC Class Codes: A61P 37/00 : Drugs for immunological or allergic disorders
• CPC Class Codes: A61P 37/04 : Immunostimulants
• CPC Class Codes: C12N 1/04 : Preserving or maintaining viable microorganisms immobilised microorganisms C12N11/00
• CPC Class Codes: C12N 1/205 : Bacterial isolates
• CPC Class Codes: C12R 2001/19 : Escherichia coli
• CPC Class Codes: Y02A 50/30 : Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

The present invention discloses: (i) a non-pathogenic probiotic microorganism and its probiotic/therapeutic uses; (ii) a formulation comprising an aqueous solution of a volatile fraction (VF) prepared from the extract of at least one plant derived material and its therapeutic uses; (iii) a process of manufacturing the formulation from the plant derived material; (iv) a probiotic composition comprising the non-pathogenic probiotic microorganism of the invention and/or other probiotic microorganism(s) and the formulation of the invention, and its probiotic/therapeutic uses; (v) a composition for industrial applications comprising the formulation of the invention and microorganism(s) of industrial applicability; and (vi) industrial processes and apparatuses in which the latter composition is used.

Claims

1. A veterinary feed additive for accelerating animal weight gain, such that an animal receiving the feed additive gains more weight at a given time as compared with a controlled animal, the feed additive comprising at least one volatile fraction (VF) of a plant extract, wherein said plant extract is obtained by water extraction and said volatile fraction being prepared by steam distillation of said plant extract under a pressure lower than atmospheric pressure and at a bath temperature not exceeding 38°

C.

2. The veterinary feed additive of claim 1, comprising distilled water and volatile fractions of beet, dill and grapefruit.

3. A food additive for accelerating weight gain in a recipient thereof, such that a recipient receiving the food additive gains more weight at a given time as compared with a controlled patient, the food additive comprising at least one volatile fraction (VF) of a plant extract, wherein said plant extract is obtained by water extraction and said volatile fraction being prepared by steam distillation of said plant extract under a pressure lower than atmospheric pressure and at a bath temperature not exceeding 38°

C.

4. The food additive of claim 3, comprising distilled water and volatile fractions of beet, dill and parsley.