System and method for monitoring progression of cardiac disease state using physiologic sensors
First Claim
1. A system for automatically monitoring the progression of a patient'"'"'s cardiac condition, comprising:
- a sensor for measuring the patients heart rate;
a physiologic sensor for measuring the patient'"'"'s physiologic data;
a memory for storing the patient'"'"'s physiologic data with respect to the patient'"'"'s heart rate;
a processor for calculating differential changes in the patient'"'"'s physiologic data stored in the memory relative to incremental changes in the patient'"'"'s heart rate; and
wherein the processor correlates the differential changes to the progression of the patient'"'"'s cardiac condition.
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Accused Products
Abstract
A system and corresponding method are provided to monitor physiological parameters associated with the progression, stabilization, or regression of symptoms of heart disease such as congestive heart failure (CHF). The monitoring is implemented by ongoing surrogate measurement of standard and direct measurements, such as daily activity and respiratory and cardiac rate response, utilizing existing implantable, rate-responsive stimulation devices that incorporate activity, respiration, and/or other sensors. The system includes a sensor that measures activity and/or minute ventilation when triggered by changes in the sensed intrinsic heart rate and/or changes in a sensor-indicated pacing rate.
265 Citations
25 Claims
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1. A system for automatically monitoring the progression of a patient'"'"'s cardiac condition, comprising:
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a sensor for measuring the patients heart rate;
a physiologic sensor for measuring the patient'"'"'s physiologic data;
a memory for storing the patient'"'"'s physiologic data with respect to the patient'"'"'s heart rate;
a processor for calculating differential changes in the patient'"'"'s physiologic data stored in the memory relative to incremental changes in the patient'"'"'s heart rate; and
whereinthe processor correlates the differential changes to the progression of the patient'"'"'s cardiac condition. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11)
oxygen content of blood, pressure, cardiac output, ejection fraction, stroke volume, end diastolic volume, end systolic volume, respiration rate and/or minute ventilation, pH of blood, or ventricular gradient.
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11. The system as recited in claim 1, wherein the memory includes a plurality of histogram bins for storing the activity data;
- and wherein
each histogram bin is assigned to a specific heart rate range.
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12. A system for automatically monitoring the progression of a patient'"'"'s cardiac condition, comprising:
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a sensor for measuring the patient'"'"'s intrinsic heart rate;
a physiologic sensor for measuring the patient'"'"'s minute ventilation data;
a memory for storing the patient'"'"'s minute ventilation data with respect to the patient'"'"'s heart rate;
a processor for calculating differential changes in the patient'"'"'s minute ventilation data stored in the memory relative to incremental changes in the patient'"'"'s heart rate; and
whereinthe processor correlates the differential changes to the progression of the patient'"'"'s cardiac condition.
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13. A system for use with a stimulation device to automatically monitor the progression of a patient'"'"'s cardiac condition, comprising:
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a sensor for measuring a stimulation rate of the stimulation device;
a physiologic sensor for measuring the patient'"'"'s activity data;
a memory for storing the patient'"'"'s activity data with respect to the stimulation rate;
a processor for calculating differential changes in the patient'"'"'s activity data stored in the memory relative to incremental changes in the stimulation rate; and
whereinthe processor correlates the differential changes to the progression of the patient'"'"'s cardiac condition.
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14. A system for automatically monitoring the progression of a patient'"'"'s cardiac condition, comprising:
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a sensor for measuring the patient'"'"'s activity data;
a physiologic sensor for measuring the patient'"'"'s physiologic data;
a memory for storing the patient'"'"'s physiologic data with respect to the patient'"'"'s activity data;
a processor for calculating differential changes in the patient'"'"'s physiologic data stored in the memory relative to incremental changes in the patient'"'"'s activity data; and
whereinthe processor correlates the differential changes to the progression of the patient'"'"'s cardiac condition.
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15. A method for automatically monitoring the progression of a patient'"'"'s cardiac condition, comprising:
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measuring the patient'"'"'s intrinsic heart rate;
measuring the patient'"'"'s activity data;
storing the patient'"'"'s activity data with respect to the patient'"'"'s heart rate;
calculating differential changes in the patient'"'"'s activity data relative to incremental changes in the patient'"'"'s heart rate; and
correlating the differential changes to the progression of the patient'"'"'s cardiac condition.
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16. A system for automatically monitoring the progression of a patient'"'"'s cardiac condition, comprising:
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means for measuring the patient'"'"'s intrinsic heart rate;
means for measuring the patient'"'"'s activity data;
a memory for storing the patient'"'"'s activity data with respect to the patient'"'"'s heart rate;
calculating means for calculating differential changes in the patient'"'"'s activity data stored in the memory relative to incremental changes in the patient'"'"'s heart rate; and
whereinthe calculating means correlates the differential changes to the progression of the patient'"'"'s cardiac condition.
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17. A system for automatically monitoring the progression of a patient'"'"'s cardiac condition, comprising:
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a sensor for measuring the patient'"'"'s heart rate;
a physiologic sensor for measuring the patient'"'"'s physiologic data, the patient'"'"'s physiologic data stored in the memory in response to a change in the patient'"'"'s heart rate;
a memory for storing the patient'"'"'s physiologic data with respect to the patient'"'"'s heart rate;
a processor for calculating differential changes in the patient'"'"'s physiologic data stored in the memory relative to incremental changes in the patient'"'"'s heart rate; and
whereinthe processor correlates the differential changes to the progression of the patient'"'"'s cardiac condition. - View Dependent Claims (18, 19, 20, 21, 22, 23, 24)
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25. A method for automatically monitoring the progression of a patient'"'"'s cardiac condition, comprising:
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measuring the patient'"'"'s intrinsic heart rate;
measuring the patient'"'"'s activity data;
storing the patient'"'"'s activity data with respect to the patient'"'"'s heart rate, the patient'"'"'s activity data stored in response to a change in the patient'"'"'s heart rate;
calculating differential changes in the patient'"'"'s activity data relative to incremental changes in the patient'"'"'s heart rate; and
correlating the differential changes to the progression of the patient'"'"'s cardiac condition.
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Specification