Nanotechnology for biomedical products

• US 6,572,672 B2
• Filed: 05/17/2002
• Issued: 06/03/2003
• Est. Priority Date: 11/06/1998
• Status: Expired due to Term

• Current Assignee: PPG Industries Ohio Incorporated (Nouryon BV)
• Original Assignee: NanoProducts Corporation (Nouryon BV)
• Inventors: Yadav, Tapesh, Au, Ming, Miremadi, Bijan, Freim, John, Avniel, Yuval, Dirstine, Roger, Alexander, John, Franke, Evan
• Primary Examiner(s): Le, H. Thi
• Application Number:
  US10/147,829
• Publication Number:
  US 20020164482A1
• Time in Patent Office: 382 Days
• Field of Search: 753/43, 753/51, 424/400, 424/422, 424/489, 424/78.08, 424/617, 428/402, 428/407
• US Class Current: 75/343
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Abstract

Nanostructured non-stoichiometric materials are disclosed. Novel biomedical materials and their applications are discussed. More specifically, the specifications teach the use of nanotechnology and nanostructured materials for developing novel biomedical products.

Claims

1. A method of preparing a biomedical implant comprising:

mechanical alloying powders of selected metals to prepare non-stoichiometric non-equilibrium nanoscale alloy powders;

pressing the nanoscale powders to form the biomedical implant.

2. The method of claim 1 wherein the selected metals are non-toxic.

3. A method of bio-active material delivery comprising:

providing a metal containing substance;

converting the metal-containing substance into a non-stoichiometric non-equilibrium crystalline nanomaterial;

adding at least one selected bio-active material to the nanomaterial to form a bio-active material loaded nanomaterial;

preparing a bio-active material carrying carrier comprising the bio-active material loaded nanomaterial; and

implementing bio-active material delivery by administering the bio-active material carrying carrier by a method selected from the group consisting of;

oral administration, topical administration, injection and implantation.

4. The method of claim 3 wherein the nanomaterial comprises a magnetic material.

5. The method of claim 3 wherein the nanomaterial comprises a photocatalytic material.

6. The method of claim 3 wherein the bio-active material comprises a drug.

7. The method of claim 3 wherein the bio-active material comprises a marker.

8. The method of claim 3 further comprising coating the bio-active material loaded nanomaterials with a polymer.

9. The method of claim 3 wherein preparing the bio-active material carrying carrier comprises dissolving the bio-active material loaded nanomaterial in a solvent.