Active implantable medical device for treating sleep apnea syndrome by electrostimulation
First Claim
1. A cardiac stimulation device for treating the syndrome of the sleep apnea of a patient by electrostimulation comprising:
- means for measuring the respiratory activity of the patient having an output signal representative of the patient'"'"'s respiratory activity;
means for analyzing the patient'"'"'s respiratory activity according to the output signal from the respiratory measuring means to determine an occurrence of an apnea;
means for determining a cardiac rate of the patient, including a second rate in the absence of a determined apnea;
means for stimulation, controlled by the analyzing means, to apply selectively to the patient cardiac stimuli at a first rate in the event of a detection of an apnea, said first rate being higher than the second rate;
means for determining a state of activity of the patient, said state being selected, according to predetermined criteria, from among a first value representative of a sleep state of the patient and a second value representative of an awake state of the patient;
wherein the stimulation means is applying to the patient cardiac stimuli at the first cardiac rate only during a determined sleep phase.
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Accused Products
Abstract
An active implantable medical device for electrostimulation in response to a determined sleep apnea syndrome, particularly a pacemaker. This device measures the respiratory activity of the patient, using for example, a minute ventilation sensor and/or a blood oxygen saturation sensor, and analyzes the sensor signal, to determine occurrence of an apnea according to the signal delivered by the sensor. The device also delivers an increase cardiiac pacing rate in the event of detection of apnea. The device also can deliver a neurological and/or cardiac stimulation so as to apply selectively to the patient an electric stimulus. The device also determines the patients'"'"'s state of activity, according to predetermined criteria, such that the increased pacing rate is provided only during a sleep phase and otherwise inhibited. The analysis can in particular detect and occurrence of successive apnea during a phase of sleep and determine the occurrence of a sleep apnea syndrome when the number of apnea events detected during a given period of time exceeds a predetermined threshold.
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Citations
31 Claims
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1. A cardiac stimulation device for treating the syndrome of the sleep apnea of a patient by electrostimulation comprising:
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means for measuring the respiratory activity of the patient having an output signal representative of the patient'"'"'s respiratory activity;
means for analyzing the patient'"'"'s respiratory activity according to the output signal from the respiratory measuring means to determine an occurrence of an apnea;
means for determining a cardiac rate of the patient, including a second rate in the absence of a determined apnea;
means for stimulation, controlled by the analyzing means, to apply selectively to the patient cardiac stimuli at a first rate in the event of a detection of an apnea, said first rate being higher than the second rate;
means for determining a state of activity of the patient, said state being selected, according to predetermined criteria, from among a first value representative of a sleep state of the patient and a second value representative of an awake state of the patient;
wherein the stimulation means is applying to the patient cardiac stimuli at the first cardiac rate only during a determined sleep phase. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8)
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9. A cardiac stimulation device for treating a sleep apnea syndrome of a patient by electrostimulation comprising:
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means for determining a state of activity of the patient, said state being selected, according to predetermined criteria, from among a first value representative of a sleep state of the patient and a second value representative of an awake state of the patient;
means for measuring the respiratory activity of the patient;
means for determining an occurrence of an apnea based upon said measured respiratory activity;
means for determining a cardiac rate of the patient during an identified sleep state as a second rate;
means for providing a first rate for cardiac stimulation as the second rate incremented by a first number of beats per minute; and
means for selectively applying cardiac stimulation at said first rate to the patient in response to a determined apnea during a sleep state. - View Dependent Claims (10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20)
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21. A cardiac stimulation device for treating a sleep apnea syndrome of a patient by electrostimulation comprising:
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a patient activity detector having predetermined criteria corresponding to a sleep state of a patient and an awake state of the patient, said detector monitoring patient activity and producing a first state output when the patient is in a sleep state and a second state output when the patient is in an awake state;
a respiratory activity monitor having a first activity output corresponding to a patient'"'"'s respiratory activity;
an apnea detector responsive to said first activity output for determining an occurrence of an apnea based upon said patient respiratory activity;
a cardiac rate monitor for determining a first cardiac rate of the patient in response to the patient activity monitor producing the first state output;
a cardiac stimulator having a second cardiac stimulation rate output corresponding to the determined first cardiac rate incremented by a first number of beats per minute, said stimulator applying cardiac stimulation at said cardiac stimulation rate to the patient in response to a determined apnea and the patient activity monitor producing the first state output. - View Dependent Claims (22, 23, 24, 25, 26, 27, 28, 29, 30, 31)
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Specification