Cool-tip radiofrequency thermosurgery electrode system for tumor ablation
First Claim
1. A process for the controlled ablation of tissue in the body of a subject, comprising the steps of:
- providing a housing having a portion of its surface forming a high frequency electrode and defining an inner space;
inserting an inner probe into the inner space to define a channel within the inner space;
supplying high frequency electrical energy to the outer housing for the ablation of tissue in the body of the subject;
providing circulating coolant through the channel;
monitoring audio signals, positioning a microphone adjacent the tissue and detecting the audio signals emitted by the tissue using the microphone during an ablation procedure, emanating from the tissue in the body of the subject representative of physiological changes caused by the ablation; and
dynamically controlling and maintaining a degree of high frequency electrical energy supplied to the outer housing, the degree being responsive to indications of the audio signals emanating from the body of the subject.
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Abstract
This patent application is a continuation-in-part of the patent application of the present authors related to target volume ablation in the body using a cooled-tip tissue-heating probe such as a fluid cooled (perfusion cooled) high frequency electrode. The present application relates in part to examples of specific embodiments of high frequency and radiofrequency electrode designs and heating and cooling system designs. It further describes embodiments in conjunction with 3-D or 2-D image data and computer graphic workstions to control, monitor, and pre-plan the process of target ablation. Specific examples of cooled-tip electrode constructions will be given which have utility for percutaneous or intraoperative cancerous tumor ablation. Cooled tip electrode systems with modular or separable components involving an insertion cannula, a radiofrequency electrode element, a cooling element, and a thermo-monitoring and/or radiofrequency connection electrode will be given. A high frequency and cooling system which is controlled and regulated based on the “thermally clamped tip” concept together with control of power, current, or other high frequency power parameters to pre-plan and control lesion size will be shown. Pre- or contemporaneous monitoring methods using CT, MR, ultrasound, and acoustic imaging or monitoring modalities in conjugation with the cooled tip high frequency ablation system will be exemplified. Variations in electrode design for specific target sites in the body will be described and illustrated.
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Citations
14 Claims
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1. A process for the controlled ablation of tissue in the body of a subject, comprising the steps of:
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providing a housing having a portion of its surface forming a high frequency electrode and defining an inner space;
inserting an inner probe into the inner space to define a channel within the inner space;
supplying high frequency electrical energy to the outer housing for the ablation of tissue in the body of the subject;
providing circulating coolant through the channel;
monitoring audio signals, positioning a microphone adjacent the tissue and detecting the audio signals emitted by the tissue using the microphone during an ablation procedure, emanating from the tissue in the body of the subject representative of physiological changes caused by the ablation; and
dynamically controlling and maintaining a degree of high frequency electrical energy supplied to the outer housing, the degree being responsive to indications of the audio signals emanating from the body of the subject. - View Dependent Claims (2, 3, 4, 5, 6, 7)
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8. A process for the controlled ablation of tissue in the body of a subject, comprising the steps of:
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providing a housing having a portion of its surface forming a high frequency electrode and defining an inner space;
inserting an inner probe into the inner space to define a channel within the inner space;
supplying high frequency electrical energy to the outer housing for the ablation of tissue in the body of the subject;
wherein the high frequency electrode further comprises a first hemispherical portion and a second opposed hemispherical portion wherein the first hemispherical portion is electrically conductive and the second hemispherical portion is electrically insulated and wherein, during the step of supplying, the first hemispherical portion causes ablation of tissue adjacent thereto that extends in a direction opposite the second hemispherical portion;
providing circulating coolant through the channel;
monitoring audio signals, during an ablation procedure, emanating from the tissue in the body of the subject representative of physiological changes caused by the ablation; and
dynamically controlling and maintaining a degree of high frequency electrical energy supplied to the outer housing, the degree being responsive to indications of the audio signals emanating from the body of the subject.
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9. A process for the controlled ablation of tissue in the body of a subject, comprising the steps of:
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providing a housing having a portion of its surface forming a high frequency electrode and defining an inner space;
inserting an inner probe into the inner space to define a channel within the innerspace;
supplying high frequency electrical energy to the outer housing for the ablation of tissue in the body of the subject;
wherein the housing comprises an outer cannula having a closed tip portion disposed at its distal end, the tip portion further comprising a first hemispherical portion and a second opposed hemispherical portion, the first hemispherical portion forming the high frequency electrode and the second hemispherical portion being insulated and wherein, during the step of supplying, the first hemispherical portion causes ablation of tissue adjacent thereto that extends in a direction opposite the second hemispherical portion;
providing circulating coolant through the channel;
monitoring audio signals, during an ablation procedure, emanating from the tissue in the body of the subject representative of physiological changes caused by the ablation; and
dynamically controlling,.and maintaining a degree of high frequency electrical energy supplied to the outer housing, the degree being responsive to indications of the audio signals emanating from the body of the subject. - View Dependent Claims (10, 11, 12, 13, 14)
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Specification