Method and system for reducing background artifacts from uniformly redundant array collimators in single photon emission computed tomography

• US 6,580,939 B1
• Filed: 10/31/2000
• Issued: 06/17/2003
• Est. Priority Date: 11/04/1999
• Status: Active Grant

• Current Assignee: Board of Regents of the University of Texas System (University of Texas System)
• Original Assignee: Board of Regents of the University of Texas System (University of Texas System)
• Inventors: Vassilieva, Olga, Chaney, Roy C.
• Primary Examiner(s): Walberg, Teresa
• Assistant Examiner(s): DAHBOUR, HENRY
• Application Number:
  US09/702,716
• Time in Patent Office: 959 Days
• Field of Search: 600/425, 600/426, 600/427, 600/428, 600/429, 600/431, 600/1, 600/587, 600/436, 606/10, 250/363.02, 250/363.1, 250/363.06
• US Class Current: 600/425
• CPC Class Codes: G01T 1/1648 Ancillary equipment for scintillation cameras, e.g. reference markers, devices for removing motion artifacts, calibration devices adapted for flow studies G01T1/1647

Abstract

An apparatus and method is disclosed for use in medical imaging including a collimator having an array of positive apertures and an array of negative apertures formed thereon. A housed collimator directed at a detector to essentially eliminate all gamma radiation except that which enters the apertures of the collimator is used. During an imaging operation, a first image of a targeted photon source is generated through the collimator portion having a positive aperture arrangement. A second image of the targeted photon source is generated through the collimator portion having a negative aperture arrangement, wherein the first and second generated images are summed. The summation of these images causes a significant fraction of background artifacts to be reduced from a resulting summed representation of a targeted photon source.

Claims

1. A collimator for use in medical imaging wherein substantial reduction of background artifacts is desired, said collimator comprising:

a positive aperture portion having an array of positive apertures formed thereon; and

a negative aperture portion having an array of negative apertures formed thereon.

2. The collimator of claim 1, further comprising:

a housing for the aperture and detector that shields photons from all directions except for the aperture portions of the collimator;

a slot formed within said housing for holding the collimator in direct orientation with a field of photon energy received through a specimen targeting window wherein said slot allows movement of the collimator in such a manner as to detect photons from a source with said positive aperture and negative aperture portions; and

wherein the collimator is held within said slot such that one of the aperture portions is oriented to receive photons emanating from a source, and wherein the collimator is movable within said slot to allow the other negative aperture portions to also be oriented to receive photons emanating from a source.

3. The collimator of claim 2, further comprising a detector for receiving photons passing through the positive and negative apertured portions of the collimator, the detector counts the number of photons passing through the positive and negative collimators to produce positive and negative images, and for summing the positive and negative images to render a final image.

4. The collimator of claim 3, wherein said said collimator further comprises a plurality of apertures formed within said collimator having a radius in the range from 1 mm to 5 mm.

5. The collimator of claim 2, wherein said housing and said collimator are formed from substantially lead-based or heavy Z material.

6. The collimator of claim 1, wherein said collimator comprises a substantially lead-based or heavy Z material.

7. A medical imaging system, comprising:

a housing having first and second ends, said housing substantially shielding a detector from interfering photon sources, wherein said first end forms an opening for directing photon energy from a monitored source into said housing through a collimator and said second end comprises a detector for receiving photon energy;

a collimator at said first end having positive and negative apertured sections, the collimator being movable within the slot to independently expose either said positive or said negative apertured sections to a photon energy source located near said first end during imaging operations; and

a detector for receiving photon energy through said housing and said collimator at said second end.

8. The medical imaging system of claim 7, wherein said collimator comprises lead-based or heavy Z material.

9. The medical imaging system of claim 8, wherein said housing comprises lead-based or heavy Z material.

10. The medical imaging system of claim 7, further comprising a detector for receiving photons passing through said positive and negative apertured portions of said collimator, said detector for converting said photons into a positive image and a negative image, wherein said positive and said negative image are summed to render a final image.

11. The medical imaging system of claim 9, wherein said said collimator further comprises a plurality of apertures formed within said collimator having a radius in the range from 1 mm to 5 mm.

12. A method of single photon emission computing tomography, comprising the steps of:

receiving a first image from a photon source through a collimator having a positive aperture array;

receiving a second image of said photon source through a collimator having a negative aperture array; and

digitally summing said first and second images thereby resulting in a representation of said photon source from said first and second images wherein background artifacts are substantially removed from a representation of the image.

13. The method of claim 12, wherein the source of said photons being detected is an internal organ.

14. A method for medical imaging comprising:

receiving a first image from a SPECT scan of an object through a coded aperture array collimator, the image being the attenuation of photons in an object;

reversing said aperture, thereby reversing opaque region from non-opaque regions;

receiving a second image from a SPECT scan of the object through said reversed aperture; and

creating a composite image nearly representing said object by adding said first and second images, thereby substantially reducing background artifacts from the emission of photons representing said object.

15. The method of claim 14, wherein said adding of first and second images results in signal increase that is a factor of two.

16. The method of claim 14, wherein the source of said photons being detected is an internal organ.

17. The method of claim 14, wherein the source of said photons being detected is a breast.

18. The method of claim 14, wherein the source of aid photons being detected is a heart.

19. The method of claim 14, wherein the source of aid photons being detected is a brain.

20. The method of claim 14, wherein the source of said photons being detected is a human limb.