Compensating drug delivery system
First Claim
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1. A device for delivery of a liquid medicament to a subject comprising:
- a reservoir for containing the liquid medicament under pressure;
a needle for penetrating the skin of the subject;
a flow tube in fluid communication with the needle and the reservoir;
a memory device for storing a schedule of delivery of the liquid medicament to a subject in terms of dose or dosing rate or both dose and dosing rate as a function of time;
a meter for measuring properties of flow in the tube; and
a valve for starting and stopping liquid flow in the flow tube in a periodic manner;
wherein the time the valve is open or closed each period is adjusted to compensate for changes in system parameters as determined by measurements made by the meter so that the schedule of delivery is followed.
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Abstract
A compensating drug delivery system for delivery of medicaments to animals is described. A drug-containing reservoir is connected to a needle array through a flow tube. Medicament delivery to the animal through this flow tube is regulated by the combined action of a metering means and a valving means, and inaccuracies in delivery rate are compensated. The metering means and the valving means are microprocessor controlled to insure that the medication administered is according to a pre-established protocol.
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Citations
23 Claims
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1. A device for delivery of a liquid medicament to a subject comprising:
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a reservoir for containing the liquid medicament under pressure;
a needle for penetrating the skin of the subject;
a flow tube in fluid communication with the needle and the reservoir;
a memory device for storing a schedule of delivery of the liquid medicament to a subject in terms of dose or dosing rate or both dose and dosing rate as a function of time;
a meter for measuring properties of flow in the tube; and
a valve for starting and stopping liquid flow in the flow tube in a periodic manner;
whereinthe time the valve is open or closed each period is adjusted to compensate for changes in system parameters as determined by measurements made by the meter so that the schedule of delivery is followed. - View Dependent Claims (2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 20, 21, 22, 23)
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15. A method of delivering a liquid medicament to a subject including the steps of
a) providing a two component drug delivery device wherein the first component comprises a reservoir for containing a liquid medicament under pressure, a needle for penetrating the skin of the subject, and a flow tube connecting the reservoir and the needle, and wherein the second component is matable with the first component and comprises a valve for starting and stopping flow in the tube, a memory device for storing a delivery schedule for the liquid medicament in terms of dose or dosing rate or both dose and dosing rate as a function of time, and a meter for measuring properties of the flow of the liquid medicament along the flow tube, b) using the meter to make measurements of a property of flow of the liquid medicament, and c) using the measurements of a property of flow to deliver the liquid medicament according to the schedule by adjusting the time that the valve is open or closed to compensate for changes in system parameters.
Specification