Drug delivery device having improved adhesion and attachment system for drug delivery device

• US 6,585,707 B2
• Filed: 05/20/1999
• Issued: 07/01/2003
• Est. Priority Date: 05/21/1998
• Status: Expired due to Term

• Current Assignee: Elan Pharma International Limited (Perrigo Company PLC)
• Original Assignee: Elan Pharma International Limited (Perrigo Company PLC)
• Inventors: Etheredge, Robert, Danon, Haim, Katz, David, Gross, Joseph, Rozanowich, Mario, Cabiri, Oz, Tsals, Izrail, Brodeur, Craig
• Primary Examiner(s): Casler, Brian L.
• Assistant Examiner(s): Thompson, Michael M
• Application Number:
  US09/315,629
• Publication Number:
  US 20010056262A1
• Time in Patent Office: 1,503 Days
• Field of Search: 604/174, 604/180, 604/513, 604/41, 604/151, 604/93, 604/304-308, 604/386-387, 602/41, 602/53, 602/58, 602/52, 602/54-57, 128/DIG.26
• US Class Current: 604/307
• CPC Class Codes: A61M 2025/0253 where the catheter is attached by straps, bands or the like secured by adhesives
• CPC Class Codes: A61M 2025/0266 using pads, patches, tapes or the like
• CPC Class Codes: A61M 25/02 Holding devices, e.g. on the body
• CPC Class Codes: A61M 5/14248 of the skin patch type

Abstract

A system adapted to be disposed between a rigid or semi-rigid device and human skin for reliably attaching the device to the skin for an extended period of time. The system includes a skin-contacting surface for adhering to human skin, and an opposed surface for attachment to a rigid or semi-rigid device. The system is attached along its opposed surface to a portion of the total area of the adjacent surface of the device. When the device is subjected to external stress, the stress is transmitted through the area of attachment and distributed to the unattached area. This minimises stress on the skin and reduces the chance of detachment from the skin.

Claims

1. An attachment system for reliably attaching a device to the skin of a being and wherein the device includes a rigid or semi-rigid base having a periphery, said system comprising:

a structure having a skin-attaching surface and a base-attaching surface, said skin-attaching surface comprising an adhesive for adhering to the skin of the being, said skin-attaching surface having a periphery larger than the periphery of said rigid or semi-rigid base; and

said base-attaching surface having a central region and a peripheral edge and wherein said base-attaching surface is coupled to said rigid or semi-rigid base at discrete adhesive locations but is uncoupled to said rigid or semi-rigid base at its central region and at its peripheral edge, thereby minimizing stress omnidirectionally on the skin of the being and reducing the chance of premature detachment from the skin of the being.

2. The attachment system according to claim 1, wherein one portion of said peripheral edge is coupled to said rigid or semi-rigid base by adhesive.

3. The attachment system according claim 2, wherein said one portion forms an extension of one said discrete adhesive locations.

4. The attachment system of claim 1, wherein said structure forms a flexible skirt around each of said discrete adhesive locations.

5. The attachment system according to claim 1, wherein said skin-attaching-surface comprises a pressure sensitive adhesive.

6. The attachment system according to claim 1, wherein said structure comprises a carrier element having viscoelastic properties approaching those of skin.

7. The attachment system according to claim 1, wherein said discrete adhesive locations are arranged at the apices of a triangle.

8. An attachment system for reliably attaching a device to the skin of a being, and wherein the device includes a rigid or semi-rigid base having a first plurality of attachment members located thereon and a periphery, said system comprising:

a structure having a skin-attaching surface and a base-attaching surface, said skin-attaching surface comprising an adhesive for adhering to the skin of the being, said skin-attaching surface having a periphery larger than the periphery of said rigid or semi-rigid base; and

said base-attaching surface being located opposite to said skin-attaching surface and comprising a central region, a peripheral edge and a second plurality of attachment members and wherein said first and second plurality of attachment members cooperate to couple said rigid or semi-rigid base to said base-attaching surface but wherein said central region and said peripheral edge remain uncoupled to said rigid or semi-rigid base, thereby minimizing stress omnidirectionally on the skin of the being and reducing the chance of premature detachment from the skin of the being.

9. An attachment system for reliably attaching a device to the skin of a being and wherein the device includes a rigid or semi-rigid base having a periphery, said attachment system comprising:

a structure having a skin-attaching surface and a base-attaching surface, said skin-attaching surface comprising an adhesive for adhering to the skin of the being, said skin-attaching surface having a periphery larger than the periphery of said rigid or semi-rigid base;

said base-attaching surface having a central region and a peripheral edge and wherein said base-attaching surface is coupled to said rigid or semi-rigid base at discrete adhesive locations but is uncoupled to said rigid or semi-rigid base at its central region and at its peripheral edge, thereby minimizing stress omnidirectionally on the skin of the being and reducing the chance of premature detachment from the skin of the being; and

wherein a relief cavity is formed between the base and said structure which can accommodate deflection of the skin of the being in use which would otherwise result in higher stress and potential premature detachment thereof.

10. The attachment system according to claim 9 being adapted to permit the passage of a needle therethrough for delivery of a substance through the skin.

11. The attachment system according to claim 10 wherein said structure comprises a locus for permitting the needle access to the skin and wherein a flexible area is provided at the locus.

12. The attachment system according to claim 9, wherein one portion of said peripheral edge is coupled to said rigid or semi-rigid base by adhesive to facilitate removal of the base when required.

13. An attachment system for reliably attaching a device to the skin of a being, and wherein the device includes a rigid or semi-rigid base having a periphery, said system comprising:

a generally planar member having a skin-attaching surface and a base-attaching surface, said skin-attaching surface comprising an adhesive for adhering to the skin of the being, said skin-attaching surface having a periphery larger than the periphery of said rigid or semi-rigid base; and

said base-attaching surface having a central region and a peripheral edge and wherein said base-attaching surface is coupled to said rigid or semi-rigid base at discrete adhesive locations but is uncoupled to said rigid or semi-rigid base at its central region and at its peripheral edge, thereby minimizing stress omnidirectionally on the skin of the being and reducing the chance of premature detachment from the skin of the being.

14. An attachment system for reliably attaching a device to the skin of a being, and wherein the device includes a rigid or semi-rigid base having a periphery, said system comprising:

a member having viscoelastic properties approaching that of the skin of the being, a skin-attaching surface and a base-attaching surface, said skin-attaching surface comprising an adhesive for adhering to the skin of the being, said skin-attaching surface having a periphery larger than the periphery of said rigid or semi-rigid base; and

said base-attaching surface having a central region and a peripheral edge and wherein said base-attaching surface is coupled to said rigid or semi-rigid base at discrete adhesive locations but is uncoupled to said rigid or semi-rigid base at its central region and at its peripheral edge, thereby minimizing stress omnidirectionally on the skin of the being and reducing the chance of premature detachment from the skin of the being.

15. The attachment system of claim 14 wherein one portion of said peripheral edge is coupled to said rigid or semi-rigid base.

16. The attachment system of claim 15 wherein said one portion forms an extension of one of said discrete adhesive locations.