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Membrane-permeant peptide complexes for medical imaging, diagnostics, and pharmaceutical therapy

  • US 6,589,503 B1
  • Filed: 04/25/2000
  • Issued: 07/08/2003
  • Est. Priority Date: 06/20/1998
  • Status: Expired due to Term
First Claim
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1. A compound, comprising:

  • a cell membrane-permeant peptide;

    a diagnostic or pharmaceutically active substance; and

    a functional linker moiety linking said peptide and said diagnostic or pharmaceutically active substance;

    wherein said compound further comprises at least one D-amino acid and said functional linker moiety confers target cell specificity to said compound; and

    wherein said functional linker moiety interacts with intracellular components;

    or a pharmaceutically acceptable salt of said compound.

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